具有突变率的广义生-灭过程的遍历性

给出具有突变率的广义生-灭过程的遍历与指数遍历的充分必要条件，以及强遍历的充分条件。     

钒刚玉光学和磁学性质的理论研究

根据完全对角化方法和一种类晶体场模型 ,统一地解释了α- Al_2 O_3:V~(3 ) 的光谱、电子顺磁共振g因子和零场分裂D值 .理论计算值与实验符合得很好 .此外 ,导出的V~(3 ) 位置的位移量 0 .0 0 86nm与浓缩红宝石中Cr3 位置的位移量 0 .0 0 6nm相接近 .     

TNF和OA诱发人神经母细胞瘤SK细胞程序死亡

肿瘤坏死因子（ＴＮＦ）和Ｏｋａｄａｉｃａｃｉｄ（ＯＡ）能诱发人神经母细胞瘤ＳＫ细胞死亡，死亡细胞缩小变圆，细胞质凝聚，ＤＮＡ断裂形成以２００ｂＰ左右为单位的梯形分布，且上述过程可由蛋白质合成抑制剂亚胺环己酮（ＣＨＸ）抑制，显示ＴＮＦ和ＯＡ诱发的ＳＫ细胞死亡为细胞程序死亡．     

Bacterial suicide through stress

Outside of the laboratory, bacterial cells are constantly exposed to stressful conditions, and an ability to resist those stresses is essential to their survival. However, the degree of stress required to bring about cell death varies with growth phase, amongst other parameters. Exponential phase cells are significantly more sensitive to stress than stationary phase ones, and a novel hypothesis has recently been advanced to explain this difference in sensitivity, the suicide response. Essentially, the suicide response predicts that rapidly growing and respiring bacterial cells will suffer growth arrest when subjected to relatively mild stresses, but their metabolism will continue: a burst of free-radical production results from this uncoupling of growth from metabolism, and it is this free-radical burst that is lethal to the cells, rather than the stress per se. The suicide response hypothesis unifies a variety of previously unrelated empirical observations, for instance induction of superoxide dismutase by heat shock, alkyl-hydroperoxide reductase by osmotic shock and catalase by ethanol shock. The suicide response also has major implications for current [food] processing methods. Received 29 March 1999; received after revision 14 May 1999; accepted 17 May 1999     

Schiff碱H2TTAen,H2TTAdien,H2TTApn的合成和螯合性能的研究

以ＨＴＴＡ为端基与乙二胺、二乙三胺及丙二胺缩合制得Ｈ２ＴＴＡｅｎ，Ｈ２ＴＴＡｄｉｅｎ，Ｈ２ＴＴＡＰｎ３种Ｓｃｈｉｆｆ碱．它们既类似于聚酸可作多齿螯合配体，又与ｐ－二酮类似，其羰其可以异构成烯醇式，为一个二元酸．用多种近代分析测试方法对其组成和基本性质进行了表征，用ＰＨ电位法和光度法测定了酸离解常数．     

Strategies for the design of inhibitors of aldose reductase, an enzyme showing pronounced induced-fit adaptations

Aldose reductase is involved in the polyol pathway, catalyzing the reduction of glucose to sorbitol. However, due to pronounced binding site adaptations, the enzyme can operate on a broad palette of structurally diverse substrates ranging from small aliphatic and aromatic aldehydes up to steroid-type ligands. A comparative analysis of the presently accessible crystal structures of aldose reductase complexes reveals four binding-competent protein conformations. Additional relevant conformers are detected through molecular dynamics simulations. They indicate an equilibrium of several conformers which is shifted towards the binding-competent geometries upon ligand binding. Such a manifold system with several alternative binding site conformers requires some tailored concepts in virtual screening. We followed two strategies, both successfully suggesting new micromolar inhibitors. In a first attempt, we concentrated on one preferred conformer and performed a virtual screening, assuming that the binding pocket of aldose reductase adopts only this conformation. In a second approach, we followed a ligand superpositioning method. Ligands were extracted in their bound conformations from three different crystal structures, all accommodating the ligands with different active site conformations. After merging these ligands into one supermolecule, mutual alignments were computed, taking candidate ligands from a screening database. The latter strategy also retrieved several structurally new inhibitors of micromolar potency.     

关于《兄终弟继质疑》的质疑

同世界许多民族一样,历史上壮族姓氏家族观念根深蒂固,壮族社会中长期流行“兄终弟继”或称为“夫兄弟婚”的传统婚俗。侬全福与侬夏卿是侬氏家族中的远房兄弟,侬全福被交趾王杀害后,其妻阿侬投奔于侬夏卿处,并与侬夏卿结为夫妻,其后,共同支持侬智高反抗交趾和北宋王朝。这应是不争的历史事实。     

死亡与拯救 --《荒原》解读之一

死亡主题是《荒原》的核心和灵魂。但《荒原》描写的“死亡”是和生命熔铸在一起的,彼此无法分开的,即把人推向生与死的二元对立之中,着力表现处在生不如死的荒原中的人们对死的渴望,同时也孕育出“生的本能”,从而导致生死循环;这种死亡更和精神联系在一起,其中的“死亡”多以“力比多”的饥渴来对应,故死亡在这里只是一种仪式性死亡或象征性死亡,其目的是表现生命力的回归而实现精神复活,这样,艾略特就在描写死亡中完成了“拯救荒原”的主题。     

2005年1月—2009年6月煤矿死亡事故统计分析

运用数理统计的方法,对2005年1月—2009年6月国内发生的煤矿死亡事故进行了统计,从事故的类型、事故发生的时间规律、地域统计、事故发生的原因等方面,分析了煤矿事故的特点和一般规律,介绍了煤矿事故的特殊性和危害性,分析结果对提高煤矿事故的预防预测技术、制定完善的事故防范对策和应急处理预案具有重要的现实意义。     

组织卖淫罪有关问题探究

组织卖淫罪有关问题的研讨一直是刑事法界和司法实务界关注的热点之一,特别是＂强迫＂是否应成为组织卖淫行为的手段＂、他人＂是否包括男子、多名组织卖淫者之间是否有主从犯之分及其死刑的存废问题一直是学术争论的焦点。不论是从学术上还是司法实务上研讨,对该罪进行更深层次的探究具有较高的价值。因而以司法实务为切入点,主要从组织卖淫罪的特殊理论和组织卖淫罪修正的构成两个问题加以探究。