全隐式E-CUSP迎风格式大攻角分离流数值模拟

采用全隐式、低耗散E-CUSP格式,通过求解雷诺平均Navier-Stokes方程耦合Spalart-Allmaras(SA)湍流模型,模拟了细长旋成体在超声速、大攻角下的流场,分析了背风面涡的发展过程.结果表明:E-CUSP格式耦合SA湍流模型能够准确地模拟背风面的流动分离和精细的二次涡,对横向分离具有较高的模拟精度;预测的物面压力系数分布和激波位置与实验数据吻合良好,力和力矩的相对误差在1.98%之内;E-CUSP格式可用于模拟复杂的分离流动,具有高的计算精度和效率.     

基于塑性损耗的超高层建筑结构抗震性能分析

基于能量分析原理提出了一个建筑结构的塑性损耗指标,即结构的塑性损耗能在总输入能中的比例,用来衡量建筑结构在地震载荷作用下的实际损伤程度.通过有限元软件ABAQUS运用非线性动力弹塑性分析方法分析了一个典型框架—核心筒超高层结构.计算了该结构在同一地震波不同地震强度下的塑性损耗指标、构件和层的塑性损耗能分配,以及在不同地震波同一地震强度下的塑性损耗指标、层塑性损耗能分配;模拟了该结构相应的损伤破坏分布情况.两种方法表征的结果趋势一致,表明结构的塑性损耗指标和塑性损耗能分配可用来衡量结构整体和局部塑性损伤破坏情况.     

关于混凝土衬砌渠道遭受冻害的探究

山东气候是海洋性季风气候,属于季节性冻土地区,大部分地区在冬季存在混凝土衬砌渠道冻胀破坏问题。文章主要分析了混凝土衬砌渠道被冻胀破坏的几种形式和具体的成因,并提出防治冻害的措施。     

Role of Tip60 tumor suppressor in DNA repair pathway

To prevent the damage caused by DNA strand breaks, eukaryotic cells have evolved a series of highly conserved DNA repair mechanisms. The ubiquitously expressed acetyltransferase, Tip60, plays a central role in ATM (ataxia-telangiectasia mutated) activation which is involved in DNA repair. Recent work uncovered a new mechanism of ATM activation mediated by Tip60 and demonstrated that histone methylation, specifically, trimethylation of histone H3, is a key factor in the process. Here, we review the current understanding of how Tip60 is activated and how it activates ATM in response to DNA damage.     

基于有序Logistic回归模型的北京高校男生有氧能力

为探索北京高校男生有氧能力的影响因素,通过随机抽样法抽取134名18~25岁北京高校男生,空腹抽静脉血测血液指标,用德国MetaMax 3B系统实时监测气体代谢,通过线性递增方案测得VO2max相对值。基于Spearman相关、有序Logistic回归等分析方法进行分析处理。结果表明：北京高校男生有序Logistic回归方程：Ln{P(Y≤1|x)/1-P(Y≤1|x)}=-2.757-0.067*X1-0.025*X2+0.066*X3+0.018*X4-0.009*X5;Ln{P(Y≤2|x)/1-P(Y≤2|x)}=-0.771-0.067*X1-0.025*X2+0.066*X3+0.018*X4-0.009*X5（X1=体重、X2=心率(heart rate, HR)、X3=每搏输出量(stroke volume, SVI)、X4=心室射血时间(ventricular ejection time, VET)、X5=血红蛋白(hemoglobin, HGB)）。回归方程模型系数综合检验步(step)、块(block)、模型(model)检验的P值均小于0.01;拟合优度检验的-2对数似然值(-2LL)为159.374,Cox&SnellR2为0.331,NagelkerkeR2为0.373;预测等级1准确率为45.5%,等级2准确率为100%,等级3准确率为100%,综合为81.8%,说明Logistic回归模型性能良好。Hosmer和Lemeshow检验预测值与观望值无显著性差异（P>0.05）。可见北京高校男生定量负荷心功能、血液指标与有氧能力的多元Logistic回归模型拟合度较好,且HR、SVI、VET、HGB是有氧运动能力的重要预测因素。     

几个导出模型的BLU估计间的关系的研究

首先给出分块奇异模型的一种新的导出模型,得出其M2X1β的BLU估计;讨论分块模型与几个导出模型的BLU估计之间的关系,给出这几个分块导出模型的M2X1β的BLU估计相等的充要条件.     

自行火炮机动过程中毁伤和失效模拟初探

自行火炮在对抗条件下机运过程中,其损失数包含两方面：被敌方毁伤数和火炮机可靠性失效数,这两者均与火炮机动路线有关。本文用Ｍｏｎｔｅ－Ｃａｒｌｏ技术建立起机动过程中自行火炮毁伤和失效的模拟模型,并在路线选择中引入坡度选择系数和偏度选择系数概念。     

瓶颈道路使用收费的理论及模型

从经典的瓶颈模型开始,论述了道路系统达到最优使用状态的可能性及措施,提出了道路使用的动态收费策略,并对进一步扩展瓶颈模型的有关问题作了探讨.     

Cardiovascular development: towards biomedical applicability

Advances in our understanding of cardiac development have fuelled research into cellular approaches to myocardial repair of the damaged heart. In this collection of reviews we present recent advances into the basic mechanisms of heart development and the resident and non-resident progenitor cell populations that are currently being investigated as potential mediators of cardiac repair. Together these reviews illustrate that despite our current knowledge about how the heart is constructed, caution and much more research in this exciting field is essential. The current momentum to evaluate the potential for cardiac repair will in turn accelerate research into fundamental aspects of myocardial biology.     

Forward Rates,Monetary Policy and the Economic Cycle

The short end of the yield curve incorporates essential information to forecast central banks' decisions, but in a biased manner. This article proposes a new method to forecast the Fed and the European Central Bank's decision rate by correcting the swap rates for their cyclical economic premium, using an affine term structure model. The corrected yields offer a higher out‐of‐sample forecasting power than the yields themselves. They also deliver forecasts that are either comparable or better than those obtained with a factor‐augmented vector autoregressive model, underlining the fact that yields are likely to contain at least as much information regarding monetary policy as a dataset composed of economic data series. Copyright © 2015 John Wiley & Sons, Ltd.