一种新的可信修复网络模型及其实现

为解决目前缺乏一种可行的可信修复网络框架问题,提出了一种新的、可行性强的可信修复网络模型,详细说明了该模型提供的功能和工作流程,着重阐明了可信修复网络的通讯机制和认证方法.仿真实验表明,该框架在保证网络系统安全性和可信性的同时,实现了为不满足可信网络安全策略的终端用户提供及时可靠的修复服务.     

模拟退火优化BP神经网络进行云相态分类

为利用中分辨率成像光谱仪(MODIS)多通道云图数据对云相态进行分类,提出了一种利用云图红外、可见光谱段数据,基于SABP神经网络的云相态分类算法.算法基于BP人工神经网络学习算法及模拟退火算法.在两算法结合的基础上,作出了有益于云相态分类的改进.基准网络模型为3层前馈BP网络,其中,隐层和输出层使用不同的激活函数.选取了5种光谱特征作为网络输入,输出两单元判定结果.为加速收敛速度,避免振荡,采用了一种自适应的变学习系数、惯性系数策略.个例分析表明,算法在中低纬度地区效果良好.     

W玻色子极化的蒙特卡罗研究

t双轻子衰变道中,利用积分亮度为0.7fb-1的模拟数据量,通过测量W玻色子衰变末态粒子角分布的方法对其极化进行了模拟研究。最终的测量结果为:F0=0.709±0.066(syst)±0.044(stat),FL=0.297±0.077(syst)±0.026(stat),FR=-0.005±0.033(syst)±0.027(stat)。     

生活垃圾高温蒸汽消解处理工艺初探

目前我国城市生活垃圾处理工艺主要有焚烧、堆肥、卫生填埋。3种工艺均存在缺点，限制了其应用推广。介绍了一种城市生活垃圾高温蒸汽消解处理新工艺，初步分析了其消解机理、工艺特点和应用前景。     

科学学派领袖素质研究

科学史表明 ,并不是所有优秀的科学家 ,甚至包括最为杰出的科学家都能创立起自己的学派 ,这确实要取决于某些优异的个人品质。从科学社会学的角度看 ,科学学派是具有一定内在结构与功能的学术共同体 ,学派领袖在其中担负的角色必然有其相应能力上的要求。对科学学派领袖素质的研究有助于提高科研工作的组织与管理水平 ,有助于构建优秀的科研团队。     

企业服务竞争浅析

企业以追求经济效益为目的。面对信息业的高度发展，技术优势已不再是获得高额利润的惟一途径。先进的生产力一旦为不同的企业所共有，技术优势在市场竞争中常常显得苍白无力；而只有服务是一个永久常新的课题。优质的服务不但可以为企业赢得利润，而且可以为企业赢得广泛的市场，塑造企业形象，创建企业品牌。企业亦必须增强服务意识。     

Host defense against infections and inflammations: Role of the multifunctional IL-6/IFN-β2 cytokine

Summary IL-6/IFN-2 appears to be one of the important mediators of the response to viral and bacterial infections and to shock. The biological effects now associated with IL-6/IFN-2 include: stimulation of immunoglobulin secretion by mature B lymphocytes (BSF-2 activity), growth stimulation of plasmacytomas and hybridomas (HGF activity), activation of T cells, stimulation of hepatic acute phase protein synthesis (HSF activity), stimulation of hematopoiesis, cell differentiation (DIF activity), inhibition of tumor cell growth (AP activity) and other IFN-like effects. As a typical cytokine, IL-6/IFN-2 is secreted by many cell types and acts in various combinations with other interleukins and interferons.     

提高高频晶闸管di/dt耐量的研究

为提高高频晶闸管的动态指标和高频性能，通过实验分析和理论推导，研究了工艺参数和设计参数对高频晶闸管ｄｉ／ｄｔ耐量的影响。实验结果表明：较低的一扩浓度，较薄的基区宽度以及用高能电子辐照控制少子寿命，有利于提高ｄｉ／ｄｔ耐量。通过对相同工艺三种不同阴极图形的８００Ａ、１０ｋＨｚ高频晶闸管ｄｉ／ｄｔ的研究，论证了合理确定辅助晶闸管面积对提高ｄｉ／ｄｔ的重要性，并指出，在大面积高频晶闸管中设计二级放大门极，有利于提高ｄｉ／ｄｔ耐量。     

Alzheimer's disease: fundamental and therapeutic aspects

Alzheimer's disease is the most common type of progressive and debilitating dementia affecting aged people. In some early — as well as late-onset familial cases, a genetic linkage with chromosomes 14, 21 (early-onset) or 19 (late-onset) has been indicated. Furthermore, a direct or indirect role has been attributed to normal or structurally altered amyloid -protein (concentrated in senile plaques) and/or excessively phosphorylated tau protein (located in neurofibrillary tangles). Degeneration of cholinergic neurons and concomitant impairment of cortical and hippocampal neurotransmission lead to cognitive and memory deficits. Several compounds are being tested in attempts to prevent and/or cure Alzheimer's disease, including tacrine, which has very modest efficacy in a sub-group of patients, and new acetylcholinesterase inhibitors. Pilot experiments have also been launched using nerve growth factor (NGF) to prevent or stabilize the processes of cholinergic pathway degeneration. Alternatively, antioxidants, free radical scavengers and/or non steroidal anti-inflammatory agents may be screened as potential therapies for neurodegenerative diseases induced by multiple endogenous and/or exogenous factors. The recent use of transgenic mice, in parallel with other genetic, biochemical and neurobiological systems, in vivo and/or in vitro (cell cultures), should accelerate the discovery and development of specific drugs for the treatment of Alzheimer's disease.     

Genetic and molecular approaches to synthesis and action of the yeast killer toxin

Summary The K1 killer toxin ofSaccharomyces cerevisiae is a secreted, virally-coded protein lethal to sensitive yeasts. Killer yeasts are immune to the toxin they produce. This killer system has been extensively examined from genetic and molecular perspectives. Here we review the biology of killer yeasts, and examine the synthesis and action of the protein toxin and the immunity component. We summarise the structure of the toxin precursor gene and its protein products, outline the proteolytic processing of the toxin subunits from the precursor, and their passage through the yeast secretory pathway. We then discuss the mode of action of the toxin, its lectin-like interaction with a cell wall glucan, and its probable role in forming channels in the yeast plasma membrane. In addition we describe models of how a toxin precursor species functions as the immunity component, probably by interfering with channel formation. We conclude with a review of the functional domains of the toxin structural gene as determined by site-directed mutagenesis. This work has identified regions associated with glucan binding, toxin activity, and immunity.