A novel genome-wide fulllength kinesin prediction analysis reveals additional mammalian kinesins

Kinesins are microtubule-based motor proteins that perform diverse functions[1―6], including the transloca- tion of vesicles, organelles, chromosomes, proteincomplexes, RNA-binding proteins (RNPs), etc. They also help to orchestrate microtubule dynamics …     

韩中“义狗说话”比较研究

韩国和中国民间,长期以来流播着大量的"义狗说话".对两国同类型故事的梳理和分析比较,可以发现韩国"义狗说话"既受到中国民间故事的影响,同时也在许多方面有着自己的独创性.     

Porcine factor V: cDNA cloning, gene mapping, three-dimensional protein modeling of membrane binding sites and comparative anatomy of domains

Factor V is a plasma protein essential for blood coagulation. This protein is involved in activated protein C resistance, the most common inherited thrombotic disorder known. We utilized the polymerase chain reaction to clone the porcine factor V gene by generating overlapping clones amplified with primers chosen by comparison with known nucleotide sequences. The porcine factor V cDNA contig encodes a predicted 2258-amino acid protein, making it the largest in comparison to the bovine, human, and murine proteins. Porcine factor V has the highest level of homology with bovine factor V, but also has high levels of conservation of important residues with all the species. Radiation hybrid mapping assigned the porcine factor V gene to chromosome 4. Three-dimensional models of factor V were generated and used to analyze membrane-binding sites in terms of conserved, and therefore likely important residues. Received 3 October 2000; revised 23 November 2000; accepted 6 December 2000     

Protein folds: molecular systematics in three dimensions

Advances in methods of structure determination have led to the accumulation of large amounts of protein structural data. Some 500 distinct protein folds have now been characterized, representing one-third of all globular folds that exist. The range of known structural types and the relatively large fraction of the protein universe that has already been sampled have greatly facilitated the discovery of some unifying principles governing protein structure and evolutionary relationships. These include a highly skewed distribution of topological arrangements of secondary-structure elements that favors a few very common connectivities and a highly skewed distribution in the capacity of folds to accommodate unrelated sequences. These and other observations suggest that the number of folds is far fewer than the number of genes, and that the fold universe is dominated by a small number of giant attractors that accommodate large numbers of unrelated sequences. Thus all basic protein folds will likely be determined in the near future, laying the foundation for a comprehensive understanding of the biochemical and cellular functions of whole organisms.     

心灵的传承——试论《简爱》对《蝴蝶梦》的影响

本文以新的视角,对欧洲两部著名文学作品《简爱》与《蝴蝶梦》进行了详尽的比较分析,并从人物刻画、结构设置和艺术处理等多方面入手,剖析了作品成功的审美因素,进而透视出了文学遗产复杂微妙的继承关系。     

Dealing with a Differentiated Whole: The Philosophy of the WSR Approach

This paper seeks to explore a philosophical ground for the formulation and practice of an Oriental systems methodology, the wuli–shili–renli approach (WSR). Drawing insights from ancient Chinese thought, WSR contends that, in sociotechnical systems design/management, we should investigate and follow wuli, shili, and renli, which constitute a differentiable, dynamic whole. Wuli, shili, and renli condition and determine the fate of our projects, meaning different methods are needed to deal with each differentiable aspect. It also points out that, to deal with wuli, shili, and renli properly, we need to engage in encounters with the "dark side" of Confucianism and with the contemporary tendency of scientism.     

农业技术进步对中西方历史灾荒的影响

中西方灾荒历史灾荒均产生了严重的社会后果，在灾荒威胁下，农业技术水平、农业生产结构、农业发展状况等因素方面存在的差异直接影响到自然灾害的成灾后果。农业技术的进步在预防和控制灾荒的活动中发挥了重大作用，中国传统农业科技在一定程度上控制了灾情的蔓延，减轻了灾害的破坏和威胁；也是由于农业技术的落后，欧洲农业遭受灾荒后往往一蹶不振。中国农业发展的整体一致性既有利于技术的普及推广和传播，但也为农业灾荒的发生创造了条件。     

基于比较优势的吉林省种植业结构调整

对吉林省主要农作物的效率比较优势指数、规模比较优势指数和综合比较优势指数进行了计算和分析,结果表明吉林省在玉米、水稻等大宗农作物生产效率上同全国相比没有明显优势;甜菜、烟叶、油料、麻类等经济作物同全国相比处于劣势;玉米、高粱、大豆、甜菜4种作物同全国相比有规模优势,且玉米、高粱优势较大,其它作物处于劣势;吉林省玉米、高粱、大豆同全国相比具有综合比较优势,其它作物处于劣势。将吉林省各地区主要农作物的综合比较优势指数划分为4级,与之相对应调整措施,从而确定了各地区的优势组合,为各地区提出了农作物种植结构调整方向。表10,参16。     

基因组学领域演进的科学计量研究

该研究分析了当前生命科学中最具理论与应用价值的研究领域基因组学1991 — 2006 年在知识维
度上的演进过程。研究以Web of Science 数据库的论文数据为基础，对基因组学领域高频关键词的共现
矩阵进行了分析：三个不同时间段的多维尺度分析表明，处于不同发展阶段的关键词之间亲疏关系存在规
律性特征，对这些特征的分析进一步可以揭示该领域目前所处的发展阶段；此外，不同阶段共现矩阵的因
子分析展现了研究主题在时间轴上的变迁。数据分析表明：利用科学计量方法对基因组学演进过程进行研
究可以挖掘大量有用的信息。     

现代汉语中谓词作主、宾语的英译问题

现代汉语中谓词可以直接作主语和宾语。英译时可借助于词缀、动名词等方法。这些方法使对应于汉语谓词的英语词汇具有名词性质,即英语名物化的结构。最后对英汉两种语言的谓词作了对比研究。