乳酸甲氧苄啶合成工艺初探

对乙醇法和水媒法合成乳酸甲氧苄啶的工艺进行了对比试验，并对二者的收率和成本等因素做了具体的分析研究，目的是探索一条最佳合成工艺流程。     

矿山酸性废水的形成机理及防治途径初探

硫化矿系的矿山在开采过程中常常产生含有金属硫酸盐的矿山酸性废水。这些酸性废水在井下腐蚀管道和设备，危害矿工健康，危害矿工健康；在地面污染地表水，破坏水生和陆生生态环境。本文根据微生物学，化学动力学和化学热力学的理论，探讨矿山酸性废水的形成机理和影响因素，并提出一些防治措施。     

核酸序列非编码区关联长度的计算

首次计算ＤＮＡ非编码区的关联长度，发现７０％左右的序列关联长度≤２，约１５％的序列具有中程关联，约１５％的序列为长程关联，并作了初步的理论解释。     

三氧化硫磺化工艺的计算

通过对三氧化硫磺化工艺的计算，技术人员能够比较容易掌握磺化工序各物料的消耗情况，为磺化工艺调节提供理论依据，同时有利于成本控制和物料衡算。     

液压及润滑管道循环酸洗、冲洗装置的研制与应用

在安装冶金轧钢设备的液压及润滑系统管道时,原工艺多是采用配管→安装→拆除→酸洗→安装→循环冲洗,现设计了将循环酸洗和冲洗装置合二为一的液压及润滑管道循环酸冲洗装置,提出了该装置的使用方法和配套措施,并用于马钢热轧薄板连铸连轧工程的液压及润滑管道施工,既减少了投资,又缩短了工期.     

视黄酸受体γ基因的研究进展

对视黄酸受体家族、视黄酸受体γ基因和视黄酸受体γ同工型基因的结构以及视黄酸受体γ的表达与调控等方面进行了综述．     

钯(Ⅱ)与二溴对甲基偶氮甲磺显色反应的研究

钯(Ⅱ)与二溴对甲基偶氮甲磺在硝酸介质中形成组成比为1∶2的绿蓝色的配合物,其最大吸收波长位于620nm处,表观摩尔吸光系数6ε20=4.2×104L.mol-1.cm-1,钯的质量浓度在0.00~0.80mg.L-1范围内符合比尔定律.该法常温下可在水相中直接测定微量钯,并应用于废钯催化剂回收液中钯含量的测定.     

PEN固相缩聚结晶动力学的研究

研究了结晶反应过程,根据密度法测定的结果,得到PEN切片结晶Avrami指数值为2.32,反应的最佳温度为70℃,并得到结晶动力学方程。     

Inhibition of DNA restrictive endonucleases and Taq DNA polymerase by trimalonic acid C60

Activities of trimalonic acid fullerene (TMA C_60) on DNA restrictive enzymatic reaction were investigated by using two restrictive endonucleases Hind III and EcoR I and plasmid pEGFP-N1 with single restric-tive site for both enzymes. Meanwhile, TMA C60 was also tested to clarify its effects on polymerase chain reaction (PCR) with the catalyst of Taq DNA polymerase and the template of plasmid pEGFP-N1. The products from restrictive reactions or PCR were detected by agarose gel electrophoresis. It was found that the product amounts from restrictive reactions or PCR decreased significantly with addition of TMA C60. The inhibition by TMA C60 was dose-dependent and IC50 values for reactions of Hind III, EcoR I and PCR were 16.3, 6.0 and 6.0 μmol/L, respectively. Addition of two scavengers of reactive oxygen species (ROS), L-ascorbic acid-2-phosphate ester magnesium and sodium azide at the con-centrations of 2―10 mmol/L did not antagonize the activities of TMA C60 against PCR and two restrictive reactions. However, increase of Taq DNA polymerase amounts in PCR system antagonized the activities of TMA C60. These data implied that TMA C60 was able to inhibit the activities of the three above-mentioned enzymes involved in DNA metabolism, and that this inhibition probably did not correlate to ROS.