虚拟战场环境中地形编码技术的研究与实现

详细讨论了虚拟战场环境仿真系统中地形编码的原理及技术实现。提出了一种简单的判断点在三角形内的方法,采用不规则三角形作为地形编码的基本结构单元,并结合地形分块思想,实现了对地形编码的实时仿真。本文的思想和方法对同类系统的开发具有借鉴意义。     

少量高血压脑出血微创手术与保守治疗疗效对比研究

目的比较微创血肿清除术与保守治疗少量血肿(30 m L)的高血压脑出血患者临床疗效.方法将临床确诊为颅内深部少量出血的96例高血压患者作为研究对象.将所有研究对象随机分为两组:微创手术治疗组(微创组)(50例患者)和保守治疗组(对照组)(46例患者).微创组采用微创穿刺血肿清除术对高血压脑出血患者颅内血肿进行微创穿刺清除,对照组给以常规药物保守治疗.通过检测神经功能缺损评分、Glasgow昏迷评分、死亡率、再出血率、平均住院时间和格拉斯哥预后(GOS)评分情况,对两组患者的临床疗效和短期预后进行对比分析.结果 1)神经功能缺损评分结果显示:微创组患者神经功能恢复程度显著优于对照组,两组数据比较差异显著,具有统计学意义(P0.05).2)患者入院1周后Glasgow昏迷评分(GCS)检测结果显示:微创组明显好于对照组,两组数据比较差异显著,具有统计学意义(P0.05).3)微创组再出血的发生率较对照组相比有增高的趋势(P0.05),死亡率两组数据比较无显著统计学意义(P0.05).4)微创组患者平均住院时间要短于对照组(P0.05).5)采用格拉斯哥预后(GOS)评分系统对出院半年后患者的生存质量进行评估,结果显示微创组GOS得分情况明显高于对照组,两组数据比较差异显著,具有统计学意义(P0.05).结论 1)微创手术治疗能明显改善少量血肿的高血压脑出血患者意识状态和神经功能障碍,促进功能恢复,缩短患者平均住院时间,患者的短期预后和恢复效果明显.2)微创血肿清除术能显著缩短少量血肿的高血压脑出血患者住院时间,减少患者住院费用,有助于缓解患者经济负担.     

大规模多域光网络中带有多参数拟合的跨域路径计算策略

摘要： 为解决复杂多域光网络寻路时间长、业务阻塞高的问题,提出了一种在多域光网络中基于最小二乘法拟合的路径计算策略.通过单节点拓扑汇聚将多域网络抽象为低复杂的虚拟拓扑,并采用最小跳数方法计算出源宿节点的多条域序列;联合考虑域间多个资源参数的约束,基于最小二乘法将域序列拟合为不同圆心点;设定权值公式选出最优圆心点,即最优域序列;按照选定的域序列进行业务路由.仿真表明,所提策略在保证较短的路径计算时间前提下,有效地降低了多域光网络的业务阻塞率.     

Research on assessing compression quality taking into account the space-borne remote sensing images

According to the remote sensing image characteristics,a set of optimized compression quality assessment methods is proposed on the basis of generating simulative images.Firstly,a means is put forward that generates simulative images by scanning aerial films taking into account the space-borne remote sensing camera characteristics(including pixel resolution,histogram dynamic range and quantization).In the course of compression quality assessment,the objective assessment considers images texture changes and mutual relationship between simulative images and decompressed images,while the synthesized estimation factor(SEF) is brought out innovatively for the first time.Subjective assessment adopts a display setup — 0.5mm/pixel,which considers human visual characteristic and mainstream monitor.The set of methods are applied in compression plan design of panchromatic camera loaded on ZY-1-02 C satellite.Through systematic and comprehensive assessment,simulation results show that image compression quality with the compression ratio of 4:1 can meet the remote sensins aDDlication reauirements.     

可穿戴式低强度聚焦超声治疗康复贴

本文为治疗人体软组织损伤,减轻疼痛,加快病情的好转,而设计一款可穿戴式低强度聚焦超声治疗装置.该设备采用QI标准无线充电模块为整个装置提供能源,经高转换率的集成升压电路将3.3 V转为5 V,为驱动电路提供电压,再由采用nrf24l01模块传输的遥控器控制超声发生康复贴,即STM32L151单片机结合PID算法产生1 MHz PWM波,控制驱动电路驱动压电陶瓷片产生频率为1 MHz,强度为100 mW/cm²、132 mW/cm²、150 mW/cm²三档位超声波.该装置具有体积小,充电快,重量轻,成本低,无需耦合剂,可穿戴,电-声转换效率高的特点.     

家庭系统排列心理治疗研究式探索

通过对当事人的家庭系统排列，代表们的移动与对话，重新调整失序的心灵画面，可以协助当事人了解问题背后的动力和秩序，找出系统的平衡及具有爱的解决方法。     

Synthesis of pH-responsive supramolecular polypeptide nanoparticles from α-amino acids for combined chemo-photothermal therapy

A new smart supramolecular polypeptide copolymer P(Glu-co-Lys) was synthesized by the polymerization of α-amino acids using the N-thiocarboxylic acid anhydride (NTA) method, using the pH dynamic response peptide of L-glutamic acid and L-lysine as a carrier for tumor cells. The drug delivery system activated by external acid can self-assemble (pH 7.4) and disassemble (pH 5.5) under the adjustment of pH to load the drug and control its release. Doxycycline (DOX) and the photothermal reagent hydrophilic quanternary stereo-cyanine (HQS-Cy) were loaded into the peptide copolymer to obtain HQS-Cy/DOX nanoparticles (NPs) for chemo-photothermal therapy. Gentle photothermal heating can enhance the absorption of drugs by cells and enhance the efficacy of chemotherapy. In addition, chemo-photothermal therapy can solve the defect of easy recurrence after single photothermal therapy. The ingenious nanodrug delivery system of HQS-Cy/DOX NPs provides great potential for the improvement of chemo-photothermal therapy and will achieve excellent therapeutic effects in cancer treatment.     

对高校图书馆开展阅读疗法工作的思考——兼谈《阅读疗法》学习心得

介绍了阅读疗法有关情况,分析了在高校推行阅读疗法的必要性,提出了在高校推行阅读疗法的具体思路。     

Restoration of rat calvarial defects by poly（lactide-co-glycolide）/ hydroxyapatite scaffolds loaded with bone mesenchymal stem cells and DNA complexes

A composite construct comprising of a bone mesenchymal stem cell (BMSC) sheet, plasmid DNA, encoding human bone morphogenic protein-2 (hBMP-2), and poly(lactide-co-glycolide)/hydroxyapatite (PLGA/HA) sponge was designed and employed in the restoration of rat calvarial defects. To improve gene transfection efficiency, a cationic chitosan derivative, N,N,N,-trimethyl chitosan chloride (TMC), was employed as the vector. The TMC/DNA complexes had a transfection efficiency of 13% in rat BMSCs, resulting in heterogeneous hBMP-2 expression in a 10-d culture period in vitro. In vivo culture of the composite constructs was performed by implantation into rat full-thickness calvarial defects, using constructs lacking pDNA-hBMP-2 or BMSC sheets as controls. Significantly higher heterogeneous expression of hBMP-2 was detected in vivo at 2 weeks for the cell sheet/DNA complex/scaffold constructs, compared with the constructs lacking pDNA-hBMP-2 or BMSC sheets. New bone formation was evident as early as 4 weeks in the experimental constructs. At 8 weeks, partial bridging of calvarial defects was observed in the experimental constructs, which was significantly better than the constructs lacking pDNA-hBMP-2 or BMSC sheets. Therefore, the combination of the PLGA/HA scaffold with BMSC sheets and gene therapy vectors is effective at enhancing bone formation.     

线粒体病的基因治疗

线粒体基因突变导致的线粒体病仍是不治之症,目前只有针对症状的支持性疗法.根治线粒体病只能寄希望于基因治疗.基因治疗的主要目标是修补特定基因突变导致的功能缺陷,或促使异质性的转变,以降低突变型与野生型基因组的比例.所探讨的途径主要包括:①在肽核酸和锌指肽的引导下选择性抑制突变基因组的复制;②利用特定的限制性内切酶去除突变...