麦积山生态旅游资源及其营销策略

麦积山是首批国家级风景名胜区和4A级旅游区,生态旅游资源十分丰富.而开展生态旅游,则应采取加强生态保护,实现生态旅游的可持续发展;加强宣传促销活动,提高麦积山知名度;确立以生态旅游为主体的多层次、多方位大旅游观,加强与周边景区的合作与联系,扩大客源渠道,提高麦积山的可游览性等营销策略.     

面向敏捷工艺设计的任务模型及任务分派算法

工艺设计任务分派与进度监控是工艺设计活动组织管理的重要内容 ,应用计算机辅助实现这些功能是提高工艺设计活动总体敏捷性的有效途径。为开发和建立支持工艺设计任务分派与进度监控的敏捷工艺设计系统 (ACAPPS) ,提出了基于网络的分布式并行工艺设计工作模式 ,建立了该工作模式下的工艺设计任务模型 ,针对工艺设计任务的分派给出了一种最大优先分派算法。     

基于协同服务平台的分布式产品数据管理

为了实现异地设计制造环境下多产品数据管理(PDM)系统之间的数据交换、共享及其过程协同 ,在分析分布式产品数据管理特性的基础上 ,构建了一个基于协同服务平台的分布式、开放式产品数据集成管理框架结构 ,介绍了协同服务平台的功能 ,提出了多 PDM系统间的数据通信方法、安全保证机制和一致性控制策略 ,并应用于某航空产品的异地协同设计中 ,满足了协作企业对产品数据的共享要求 ,保证了数据的一致性和完整性     

A genetic algorithm on multiple sequences alignment problems in biology

The study and comparison of sequences of characters from a finite alphabet is relevant to various areas of science, notably molecular biology. The measurement of sequence similarity involves the consideration of the possible sequence alignments in order to find an optimal one for which the “distance” between sequences is minimum. In biology informatics area, it is a more important and difficult problem due to the long length (100 at least) of sequence, this cause the compute complexity and large memory require. By associating a path in a lattice to each alignment, a geometric insight can be brought into the problem of finding an optimal alignment, this give an obvious encoding of each path. This problem can be solved by applying genetic algorithm, which is more efficient than dynamic programming and hidden Markov model using commomly now. Foundation item: Supported by Zi-qiang Foundation of Wuhan University and Open Foundation of the State Key-Laboratory of Software Engineering, Wuhan University Biography: Shi Feng(1966-), male, Associate professor, research direction: bioinformatics.     

Computational manufacturing

This paper presents a general framework for computational manufacturing. The methodology of computational manufacturing aims at integrating computational geometry, machining principle, sensor information fusion, optimization, computational intelligence and virtual prototyping to solve problems of the modeling, reasoning, control, planning and scheduling of manufacturing processes and systems. There are three typical problems in computational manufacturing, i.e., scheduling (time-domain), geometric reasoning (space-domain) and decision- making (interaction between time-domain and space-domain). Some theoretical fundamentals of computational manufacturing are also discussed.     

Structural characteristics and biological functions of the HIV-1 gp120 V3 region

Recent studies demonstrate that the V3 loop of HIV-1 gp120 plays an important role in the attachment of HIV-1 to the target cells. Several amino acids in this domain are involved in the interaction of gp120 with the co-receptors. The V3 loop elicits one of the earliest antiviral antibody responses in HIV-1 infection and has been identified as the principal neutralizing determinant (PND). A subset of antibodies to V3 loop show a broad range of neutralizing activity. Unfortunately, this loop undergoes broad mutation and is one of the hypervariable regions. Mutations of some amino acids in this PND could affect syncytium formation, virus infectivity and neutralization. Knowing the structural characteristics and biological functions of the V3 region could help us to understand mechanism of HIV infection and to develop new strategy against HIV-1. In this review, the structural characteristics, variation and biological functions of the V3 loop as well as immunological responses to the V3 loop are discussed.     

A Study on Construction and Implementation of ERP System in Manufacturing Industry of Non-standard Parts

Enterprise Resource Planning (ERP) is an efficient t ool which can be used to integrate information about management of enterprise. I t has a lot of functions, such as market management, production planning, finan ce administration, quality control, personnel matters administration, electronic data exchange, business flow optimization and policy decision sustenance. With economy globalization, market internationalization, various and individual requ irement, modern enterprises become more and more to ...     

锰超氧化物歧化酶模型化合物的合成、表征及活性检测

研究近年来报道的有关锰超氧化物歧化酶及其活性部位的结构，以苹果酸，酒石酸与碳酸锰作用合成了两种超氧化物歧化酶的模型化合物，进行了红外、紫外谱图的表征，利用邻苯三酚自氧化法检测了它们的生物活性。     

高功率短脉冲激光照射下生物组织内的热传导研究

采用响应时间为1μs的超小型薄膜铂热电阻温度计及日本YOKOGAWA DL2700高速数字示波器，对微秒量级脉冲激光照射下离体动物组织内的热传导进行了实验研究，结果发现：在激光脉宽较短时，组织内出现了非傅时叶导热现象，脉宽越短，组织厚度越薄，非傅时叶导热特征越明显，功率密度和光斑直径只影响温度上升的高低，对是否会出现非傅里叶导热没有影响。     

柔性制造系统中OPN模型的建立

针对敏捷制造单元的特点,提出了一种面向对象的知识Petri网的建模方法。一方面,此方法建 立的实时控制模型可采用数学分析手段进行模型的死锁分析,另一方面,此方法将控制/决策知识融入到面 向对象Petri网中,使控制系统具有一定的智能性。