Functions of fatty acid binding proteins

Summary Cytosolic fatty acid binding proteins (FABP) belong to a gene family of which eight members have been conclusively identified. These 14–15 kDa proteins are abundantly expressed in a highly tissue-specific manner. Although the functions of the cytosolic FABP are not clearly established, they appear to enhance the transfer of long-chain fatty acids between artificial and native lipid membranes, and also to have a stimulatory effect on a number of enzymes of fatty acid metabolism in vitro. These findings, as well as the tissue expression, ligand binding properties, ontogeny and regulation of these proteins provide a considerable body of indirect evidence supporting a broad role for the FABP in the intracellular transport and metabolism of long-chain fatty acids. The available data also support the existence of structure- and tissue-specific specialization of function among different members of the FABP gene family. Moreover, FABP may also have a possible role in the modulation of cell growth and proliferation, possibly by virtue of their affinity for ligands such as prostaglandins, leukotrienes and fatty acids, which are known to influence cell growth activity. FABP structurally unrelated to the cytosolic gene family have also been identified in the plasma membranes of several tissues (FABP_pm). These proteins have not been fully characterized to date, but strong evidence suggests that they function in the transport of long-chain fatty acids across the plasma membrane.     

一种肝脏体纹理压缩方法

文章针对肝脏体纹理色彩锐变图像的局部特征,提出了基于块的游程编码和改进的S3TC混合编码方法。按照4×4像素对肝脏体纹理图像进行分块,直接抽取四种15 bits RGB565颜色作为四色查找表,而不进行插值计算,然后进行混合编码。实验证明,此算法对肝脏体纹理锐变图像较之传统的S3TC编码具有更高的压缩比和更好的图像重建品质。该方法对肝脏体纹理压缩具有较高的参考价值和实用价值。     

抗性淀粉的生物学功效及在食品加工中的应用

抗性淀粉是一种具有多种生物学功效的新型膳食纤维,且兼具类似于淀粉的优良加工特征,适合于开发品种多样的高膳食纤维功能性食品。抗性淀粉的研究与应用目前已成为国内外食品行业的热点,介绍了抗性淀粉的分类,及其在糖代谢、脂代谢、体重控制,作为益生元和防治直肠癌方面的生物学功效;分析了抗性淀粉在面包糕点、油炸食品、面条、益生菌类食品加工领域中的应用。     

甘油三脂与单纯性脂肪肝的相关分析

为探讨单纯性脂肪肝的发生与总胆固醇(TC)、甘油三脂(TG) 及血糖(PG)水平的关系.对583名离、退休人员进行全面体检,结合门诊病例资料进行横断面分析.结果显示TG及TG合并TC与脂肪肝的发病显著相关(P<0.01),而单纯TC或PG升高与单纯性脂肪肝无显著相关(P>0.05).从而得出单纯性脂肪肝的发病与高TG直接相关.     

启发式教学在脂肪酸能量计算公式推导中的应用

目的:探讨让学生推导脂肪酸能量生成的计算公式。方法:采用启发式教学法引导学生进行思考、分析、联系比较并进行归纳总结。结果:学生逐步推导出脂肪酸在分解代谢时能量的净生成数可用公式(Cn/2-1)×4+Cn/2×10-2进行计算。结论:学生在公式的推导过程中增强了学习兴趣和自信心,培养了分析问题、解决问题的能力。     

玉米油掺伪通用检验方法研究

采用玉米油、棉清油、菜籽油、棕榈油、大豆油、亚麻油为材料,分析其油脂脂肪酸组成；着重研究了玉米油掺入其它油品后脂肪酸组成的变化规律和掺伪量的计算方法,为玉米油掺伪检验提供了依据.     

Hepatic acid hydrolases of albino rats,Mastomys natalensis and albino mice duringPlasmodium berghei infection

Summary Changes in liver acid hydrolase activities during the infection of albino rats,Mastomys or mice withPlasmodium berghei are described. B-Glucosidase, B-galactosidase and N-acetyl-B-D-glucosaminidase exhibited widely different responses with acid phosphatase and cathepsin-B the least responsive and are likely to be causally related to immunity of animals.     

用碱乳化合脂的研究

本文详述了乳化液组成物和乳化工艺对乳化、乳化液的主要性能的影响,介绍了两种性能较好的碱乳合脂。此外,作者还就用碱乳化合脂的机理提出了看法。     

脂质过氧化机理及测定方法

本文对有关脂质过氧化方面的文献进行了综述,得出脂质过氧化过程的化学反应图式。讨论了多种测定脂质过氧化的方法。     

Hypersensitivity to endotoxin hepatotoxicity in rats with inflammatory lesions

Summary The ratio of sinusoidal nonparenchymal cells to hepatocytes in rat liver was significantly increased following induction of inflammation, and decreased after subsequent exposure to endotoxin, particularly in the region around the terminal portal venules. Rats with inflammatory lesions were more sensitive to endotoxin hepatocytotoxicity than normal controls, as judged from the dose-dependent increase in activity of serum transaminases and from the extent of liver tissue injury. In addition, these animals, which were already in a state of depletion of hepatic glycogen, demonstrated marked hyperglycemia 24 h after endotoxin administration in small doses of less than 2 mg/kg.