氟化氢熏气对蚕豆叶片的影响（Ⅱ）

蚕豆受氟化氢污染后,叶片含氟量与硝酸还原酶活性呈显著负相关,总氮含量也明显下降.叶绿素a、b含量下降.叶片亚细胞器也受到破坏.叶片边缘和尖端出现典型的褐色坏死伤斑,造成蚕豆产量和品质下降.     

Strain differences in the pattern and intensity of wheel running activity in laboratory rats

Summary Wheel running activity rhythms of three inbred rat strains, ACI/Ztm, BH/Ztm, and LEW/Ztm, were compared in order to evaluate the effect of genetic differences on circadian rhythm parameters. Significant strain differences were found in the general pattern of the activity rhythms and their characteristic periodicities as well as in the amount and duration of wheel running activity and the timing of activity onsets and offsets. The results suggest that genetic differences exist in the coupling of the multiple circadian oscillators that generate the overall pattern of wheel running activity.     

Malignant hyperthermia: Molecular defects in membrane permeability

Summary Malignant hyperthermia (MH), a genetically inherited disorder of skeletal muscle, is due to molecular defect in membrane permeability. The alteration in membrane permeability is suggested to be due to enhanced phospholipase A₂ activity which is responsible for the increased level in sarcoplasmic Ca²⁺. The excess Ca²⁺ is responsible for muscle hyper-rigidity and enhanced rate of glycolysis, resulting in a rapid rate of lactic acid production and a low pH in MH muscle.     

图书馆“热点”宣传探析

阐述了“热点”问题的宣传活动对于图书馆的重要意义，并从实施步骤、具体方法、注意事项等方面对图书馆“热点”问题的宣传报道活动进行了深入的探讨。     

真空镀膜实验课教学活动浅探

针对"真空镀膜" 实验课的特点和大学生的学习特点,对实验课教学活动进行了清晰简要的分析和探讨,力求达到优化教学活动和提高教学效果的目的.     

“加味八珍滋补肉食香料”扶正固本作用试验研究

本文应用小鼠增重试验、游泳试验、常压耐缺氧试验、微核试验及毒性试验对“加味八珍滋补肉食香料”的扶正固本作用进行了试验研究,以观察其增加体重、增强体力、抗应激能力、致突变及毒性等作用。结果表明:“加味八珍滋补肉食香料”具有明显提高小鼠增重量、增强体力及抗应激能力的作用,并未发现对小鼠有致突变作用及毒性反应。     

Effect of intercalating mutagens on crossing-over inDrosophila melanogaster females

Summary In order to evaluate the effect of several intercalating compounds on crossing-over inDrosophila melanogaster females, acridine orange, acriflavine, chloroquine, ethidium bromide and quinacrine were fed separately to larvae ofy ct f/+++ genotype. Our results show that acridine orange, acriflavine and ethidium bromide increase significantly the recombination frequency at thect-f region and support the view that, for intercalating agents, there is a relationship between clastogenic activity and female recombination induction.     

对企业开展合理化建议活动的总结思考

坚持开展开门纳谏活动，可以促进企业的快速发展。介绍了企业开展合理化建议活动的形式与措施。并以实例分析总结了活动所取得的效应。     

几种抗肿瘤药物对ODC的抑制作用

本文报道用酸滴定法定量测定鼠伤寒沙门氏菌鸟氨酸脱羧酶活性的方法。测定了丝裂霉素、“776”香菇多糖、博来霉素、米托葸醌、顺氨氯铂、安瘤乳口服液、环磷酰胺等抗肿瘤药物对鸟氨酸脱羧酶活性的抑制作用。此外,还测定了丝裂霉素,“776”香菇多糖、博来霉素三种抗肿瘤药物对鸟氨酸脱羧酶活性抑制作用的动力学类型。     

Isometachromin,a new cytotoxic sesquiterpenoid from a deep water sponge of the family Spongiidae

Isometachromin (1), a new sesquiterpene-quinone that is related structurally to metachromin C (2), and the known compounds ilimaquinone (3) and and 5-epi-ilimaquinone (4), were isolated from a deep water sponge in the family Spongiidae; the structure of isometachromin was elucidated by spectral methods. Isometachromin exhibits in vitro cytotoxicity against the human lung cancer cell line A 549 (IC₅₀=2.6 g/ml), but not against P 388 murine leukemia (IC₅₀10 g/ml) and also exhibits antimicrobial activity.This research is Harbor Branch Oceanographic Institution (HBOI) contribution number 911. We thank Drs S. A. Pomponi and M. Kelly-Borges (HBOI) for sponge taxonomy, and Dr P. McCarthy and T. Peterson (HBOI) for antimicrobial data.