Response of the accumulation of proline in the bodies of<Emphasis Type="Italic">Populus euphratica</Emphasis> to the change of groundwater level at the lower reaches of Tarim River

The content of proline in the plant bodies is closely related to the converse-succession-resistant capability of plants. Under the drought stress, the proline accumulates rapidly in the plant bodies for maintaining a certain mois-ture content and an expanding-pressure momentum in cells through the osmoregulation, thus the drought-resis- tant capability and the converse-succession-resistant ca-pability of plants are increased[1,2]. Many researches on the relationship between the proline and the…     

Heterogeneous reactions on the surface of fine particles in the atmosphere

Fine particles play an important role in the atmosphere. Research on heterogeneous reactions on the surface of fine particles is one of the frontier areas of atmospheric science. In this paper, physical and chemical characteristics of fine particles in the atmosphere and the interactions between trace gases and fine particles are described, methods used in heterogeneous reactions research are discussed in detail, progress in the study of heterogeneous reactions on the surface of fine particles in the atmosphere is summarized, existing important questions are pointed out and future research directions are suggested.     

Oxidative stress and hypoxia-like injury cause Alzheimer-type molecular abnormalities in central nervous system neurons

Neuronal loss and neuritic/cytoskeletal lesions (synaptic disconnection and proliferation of dystrophic neurites) represent major dementia-associated abnormalities in Alzheimer’s disease (AD). This study examined the role of oxidative stress as a factor contributing to both the cell death and neuritic degeneration cascades in AD. Primary neuron cultures were treated with H₂O₂ (9–90 μM) or desferrioxamine (2–25 μM) for 24 h and then analyzed for viability, mitochondrial mass, mitochondrial function, and pro-apoptosis and sprouting gene expression. H₂O₂ treatment causes free-radical injury and desferrioxamine causes hypoxia-type injury without free radical generation. The H₂O₂-treated cells exhibited sustained viability but neurite retraction, impaired mitochondrial function, increased levels of the pro-apoptosis gene product CD95/Fas, reduced expression of N2J1-immunoreactive neuronal thread protein and synaptophysin, and reduced distribution of mitochondria in neuritic processes. Desferrioxamine treatment resulted in dose-dependent neuronal loss associated with impaired mitochondrial function, proliferation of neurites, and reduced expression of GAP-43, which has a role in path-finding during neurite outgrowth. The results suggest that oxidative stress can cause neurodegeneration associated with enhanced susceptibility to apoptosis due to activation of pro-apoptosis genes, neurite retraction (synaptic disconnection), and impaired transport of mitochondria to cell processes where they are likely required for synaptic function. In contrast, hypoxia-type injury causes neuronal loss with proliferation of neurites (sprouting), impaired mitochondrial function, and reduced expression of molecules required to form and maintain synaptic connections. Since similar abnormalities occur in AD, both oxidative stress and hypoxic injury can contribute to AD neurodegeneration. Received 24 May 2000; received after revision 7 July 2000; accepted 27 July 2000     

4-Hydroxynonenal-modified amyloid-beta peptide inhibits the proteasome: possible importance in Alzheimer's disease

The amyloid β-peptide (Aβ) is a 4-kDa species derived from the amyloid precursor protein, which accumulates in the brains of patients with Alzheimer’s disease. Although we lack full understanding of the etiology and pathogenesis of selective neuron death, considerable data do imply roles for both the toxic Aβ and increased oxidative stress. Another significant observation is the accumulation of abnormal, ubiquitin-conjugated proteins in affected neurons, suggesting dysfunction of the proteasome proteolytic system in these cells. Recent reports have indicated that Aβ can bind and inhibit the proteasome, the major cytoslic protease for degrading damaged and ubiquitin-conjugated proteins. Earlier results from our laboratory showed that moderately oxidized proteins are preferentially recognized and degraded by the proteasome; however, severely oxidized proteins cannot be easily degraded and, instead, inhibit the proteasome. We hypothesized that oxidatively modified Aβ might have a stronger (or weaker) inhibitory effect on the proteasome than does native Aβ. We therefore also investigated the proteasome inhibitory action of Aβ _1–40 (a peptide comprising the first 40 residues of Aβ) modified by the intracellular oxidant hydrogen peroxide, and by the lipid peroxidation product 4-hydroxynonenal (HNE). H₂O₂ modification of Aβ _1–40 generates a progressively poorer inhibitor of the purified human 20S proteasome. In contrast, HNE modification of Aβ _1–40 generates a progressively more selective and efficient inhibitor of the degradation of fluorogenic peptides and oxidized protein substrates by human 20S proteasome. This interaction may contribute to certain pathological manifestations of Alzheimer’s disease Received 26 September 2000; accepted 26 September 2000     

偏、均、连三甲苯+叔丁醇体系的等压汽液平衡

用ＣＰ－Ｉ型汽液平衡双循环釜测定了叔丁醇＋偏三甲苯、叔丁醇＋均三甲苯、叔丁醇＋连三甲苯３个二元体系在压力为９９．９９２ｋ时的等压汽液平衡数据,并进行了热力学一致性检验,用Ｗｉｌｓｏｎ方程关联了实验数据,拟合精度令人满意。     

粘钢加固RC梁的锚固剪应力参数分析

在弹性理论的基础上,利用钢板固剪应力计算公式,对在集中荷载或均布荷载作用下采用粘钢加固的混凝土梁,风板锚固最大剪应力的有关影响因素。     

混凝土多轴应力状态下的徐变研究

在搜集国内外有关资料的基础上，通过对混凝土在多轴应力作用下的徐变与强度关系分析，说明在多轴应力状态下不能简单地采用叠加原理。展示了新的三轴徐变量测仪器及其徐变试验成果以及2组多轴与单轴应力状态下的徐变恢复试验成果，并对试验数据进行比较分析，得到多轴应力状态下徐变恢复与应力大小以及持荷时间之间的规律，证实了多轴应力状态下的徐变恢复与已经产生的压缩徐变有密切的关系。     

水分胁迫条件下化控物质浸种对小麦根苗生长的影响

采用水培溶液添加PEG6000模拟干旱胁迫的方式，研究了化学调控物质浸种对不同程度水分胁迫下小麦根系及幼苗生长影响。结果表明，水分胁迫不同程度地降低了小麦幼苗的株高、叶面积、地上部及根的干重、根系活力、SOD、POD活性等，并明显增加了根系MDA含量水平。化学调控物质浸种处理可以增加各种条件下小麦的总根长、叶面积、根活力及SOD与POD活性，且表现出在干旱胁迫下增加幅度高于正常处理的现象。化学调控物质浸种有利于缓解干旱胁迫带来的不良影响。利用FA、GA、MET及稀土等化学调控物质浸种具有促进根系生长、培育小麦壮苗的突出作用。图3，表2，参14。     

基于广义卡尔曼滤波的飞机防滑刹车变结构控制

飞机防滑刹车控制的关键是控制机轮的滑移率，为了使机轮工作在最佳滑移率，得到最大结合系数，提出了一种基于滑移率控制的防滑刹车变结构控制律。由于飞机滑跑时的真实速度很难测量，为此采用广义卡尔曼滤波器得到飞机刊车系统非线性模型的状态估计，状态估计值作为防滑刹车控制器的输入。计算机仿真结果显示该控制律改善了飞机的防滑刹车性能，具有较强的鲁棒性。     

基于双密度双树小波变换的超声图像降噪

针对去除斑点噪声提高超声图像质量的问题,提出双密度双树离散小波变换（DD-DT DWT）结合局部方差估计的双变量收缩阈值函数（BFS）的图像降噪改进算法实现超声图像降噪。首先将原始图像用DD-DT DWT进行多尺度分解,根据噪声模型和小波子父代系数确定的局部边缘方差估计阈值,利用子父代小波系数相关性构成的双变量阈值函数,对图像16个方向的小波系数进行非线性自适应的处理,最后重建降噪后的图像。用仿真和真实数据对此算法进行验证,并与其他小波降噪系统的性能比较,结果分析表明噪声图像经该算法降噪后,图像性能指标均有提高,不仅有效的实现图像降噪,而且较好的保留图像细节。