慢回弹聚氨酯发泡体吸声性能研究

对不同泡孔大小、不同厚度慢回弹聚氨酯材料在不同频段下的吸声性能进行实验研究.研究表明,1 300 μm是材料泡孔大小对吸声性能影响的转折点.对于低频声波,泡孔直径为1 300 μm时,吸声性能最好;对中高频声波,吸声效果最差.材料厚度对吸声性能的影响,6 cm为最优值,此时材料的吸声效果最好;材料对不同频段声波的吸收效果也各不相同,频率为1 000 Hz声波的吸收效果最差,此频率是材料吸声性能的低谷.以上研究结果为工程使用提供了有价值的实验依据.     

水下声散射信号处理可视化技术

水声散射实验需要大量的时间和经费，如果现场无法实现实验数据的处理，就难于及时获得最佳参数条件下的实验结果，当结果不理想时，需重新调整参数再做实验、为解决此类问题利用Matlab语言设计了一套水下声散射信号处理现场可视化软件．该设计提供了灵活、方便的实验参数修改功能，实现了被测目标散射特性的最佳显示效果，为水下声散射信号分析提供了依据．     

DS-CDMA中空时多用户检测算法及其性能分析

阐述了空时多用户检测的现状，介绍和分析了空时线性多用户检测算法，盲空时多用户检测等几种主要的空时多用户检测技术，并对几种空时多用户检测方法进行了误码率仿真分析，验证了空时多用户检测可以大大改善DS-CDMA系统的性能。     

Symmetrical directional cloning: An efficient method to prepare hairpin RNA interference constructs

RNA interference (RNAi) is a loss-of-function approach by which double-stranded RNA (dsRNA) initiates degradation of homologous mRNAs in a sequence specific manner. The dsRNA molecules can be produced in vitro or in vivo, and can be introduced to cells in a number of ways. Here we report a more efficient method for the cloning of inverted repeat DNA fragments into expression vectors that can be transcribed into effective dsRNA molecules in vivo or in vitro. This method, named Symmetrical Directional Cloning (SDC), takes the advantage of compatible non-palindromic restriction enezyme sites, which allow one to directionally clone a single PCR product in both the sense and antisense orientations together into a vector. SDC allows for the directional cloning of inverted repeats using a single PCR product; it requires only one cut site on each side of the loop. Hence this method is more cost effective and less time-consuming. At least 21 commercially available restriction endonucleases can be used as cloning sites for the SDC method. The efficacy of dsRNA expression vectors prepared by SDC has been demonstrated by targeting a negative regulator of the signaling pathway mediating the response of cells to phytohormone, gibberellins (GA), in the aleurone cells.     

RNA interference-mediated inhibition of Hepatitis B Virus replication

Persistent and recurrent infection of hepatitis B virus (HBV) represents one of the most common and severe viral infections of humans, and has caused a formidable health problem in the affected countries. Currently used antiviral drugs have a very limited success on controlling HBV replication and infection. RNA interference (RNAi), a process by which double-stranded RNA (dsRNA) directs sequence-specific degradation of target mRNA in mammalian and plant cells, has recently been used to knockdown gene expression in various species. In this study, we sought to determine whether RNAi-mediated silencing of HBV viral gene expression could lead to the effective inhibition of HBV replication. We first developed RNAi vectors that expressed small interfering RNA (siRNA) and targeted the HBV core or surface gene sequence. Our results demonstrated that these specific siRNAs efficiently reduced the levels of corresponding viral RNAs and proteins, and thus suppressed viral replication. Treatment with siRNA gave the greatest reduction in the levels of HBsAg (92%) and in HBeAg (85%) respectively in the cultured cell medium. Our findings further demonstrated that the RNAi-mediated antiviral effect was sequence-specific and dose-dependent. Therefore, our findings strongly suggest that RNAi-mediated silencing of HBV viral genes could effectively inhibit the replication of HBV, hence RNAi-based strategy should be further explored as a more efficacious antiviral therapy of HBV infection.     

自适应数字波束空域相干干扰抑制方法

在干扰相干背景下,接收信号协方差矩阵中信号空间的一些向量收敛到噪声空间中,仅利用二阶信息不能准确地得到干扰的方向信息,因而干扰抑制效果较差。为此,提出了一种自适应数字波束空域相干扰抑制方法。该方法是首先基于高阶累积量估计出广义方向矢量,然后根据最优均方逼近原则,结合切比雪夫加权系数形成波束,来抑制相干干扰。仿真结果表明,所提方法能够有效地抑制相干干扰。     

基于双层符号常数模的多径水声信道盲均衡算法

针对常数模算法(CMA)及符号常数模算法(SCMA)迭代中的大量乘法运算会产生延时的不足，提出了双层符号常数模算法(DSCMA)。该算法采用逐级取符号的办法，将迭代过程中的大量乘法运算转化为比较运算，大大减少了计算量。而基于双层符号常数模的多径水声信道盲均衡器，具有收敛速度快，超量均方误差和计算复杂度小等特点。用负声速梯度信道及深海信道对该盲均衡器性能进行的仿真研究表明：该盲均衡器对多径干扰有良好的抑制作用，对水下数据通信有很强的实用价值。     

透明转发器卫星通信系统在干扰条件下的互调分量

研究了有干扰时透明转发器卫星通信系统中的互调分量。首先，对有干扰时硬限幅条件下窄带系统的互调分量和DS扩频通信系统中的相关互调分量进行了理论分析；然后，针对实际系统，建立了系统仿真模型，进行了计算机性能仿真，通过对仿真结果的分析，得到一些结论。研究成果对了解透明转发器卫星通信系统在强干扰条件下存在的互调分量的影响及其量化结果，从而设计具有针对性的卫星通信抗干扰系统具有实际意义。     

水声通信中多普勒频移补偿的仿真研究

在水声通信中，收发双方存在相对运动时产生的多普勒频移将严重恶化载波恢复和符号同步。因此多普勒频移补偿是水声通信的关键技术之一，并日益受到人们的重视。提出了一种全新的、适用于收发双方存在较大相对速度时的多普勒频移检测和补偿技术。同时对与之相关的模糊度函数法、数据帧插入信号的选取、信号采样率转换、插值因子的确定与插值等问题进行了研究，通过仿真试验对多普勒频移方法进行了验证，并对其性能进行了分析。     

阻塞矩阵方法对消主瓣干扰

当存在主瓣干扰且有期望信号混入情况下,用常规自适应波束形成方法进行自适应干扰对消,不但会引起主瓣变形,而且期望信号也会被抑制,从而影响对消性能。提出一种新的阻塞矩阵方法,对接收数据进行预处理,消除它们对计算数据协方差阵的影响,再用其它方法确定自适应权值。理论分析和计算机仿真表明,用阻塞矩阵方法可以获得较大的性能提升。