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81.
嵌入式系统中USB Host功能的开发 总被引:2,自引:0,他引:2
采用自下向上的设计流程,在没有嵌入式操作系统支持的条件下,自主设计和实现了嵌入式USB Host功能.以ISP1362驱动USB海量存储类设备为例,描述了嵌入式USB Host系统的框架结构和底层驱动的设计方法.实验结果表明,遵从海量存储类子协议的USB设备,都能够被系统驱动,而且数据传输速度优于PC机驱动方式. 相似文献
82.
83.
沈元怿 《佛山科学技术学院学报(自然科学版)》2006,24(1):38-41
从实际应用的角度阐述分析了主动学习算法在资源优化分配中的应用问题,首先分析了主动学习的发展问题,并给出了主动学习的数学描述,在此基础上,重点以学生分班为例阐述了主动学习算法的应用问题。 相似文献
84.
设G是有限非可解群且Z(G)=1.如果G的非中心共轭类长为pq,p r2,qr2,那么G同构于5次交错群A5;如果G的非中心共轭类长为15,5p,15p,5p2,3p3,那么G同构于5次对称群S5. 相似文献
85.
郭畅 《重庆工商大学学报(自然科学版)》2021,38(1):113-119
针对所获取的类别不平衡的深沪A股制造业上市公司财务数据,为了预测制造业上市公司信用违约情况,提出基于欠采样改进的Lasso-Logistic模型;首先通过计算WOE和IV值,剔除风险识别能力和稳定性较差的变量,接着从"数据"层面对现有的Lasso-Logistic模型进行批量欠采样处理,最后结合"算法"层面对Lasso... 相似文献
86.
A. Fridkin A. Penkner V. Jantsch Y. Gruenbaum 《Cellular and molecular life sciences : CMLS》2009,66(9):1518-1533
87.
R. P. Massengo-Tiassé J. E. Cronan 《Cellular and molecular life sciences : CMLS》2009,66(9):1507-1517
The enoyl-acyl carrier protein reductase (ENR) is the last enzyme in the fatty acid elongation cycle. Unlike most enzymes
in this essential pathway, ENR displays an unusual diversity among organisms. The growing interest in ENRs is mainly due to
the fact that a variety of both synthetic and natural antibacterial compounds are shown to specifically target their activity.
The primary anti-tuberculosis drug, isoniazid, and the broadly used antibacterial compound, triclosan, both target this enzyme.
In this review, we discuss the diversity of ENRs, and their inhibitors in the light of current research progress.
Received 3 November 2008; received after revision 5 December 2008; accepted 8 December 2008 相似文献
88.
I. Campia E. Gazzano G. Pescarmona D. Ghigo A. Bosia C. Riganti 《Cellular and molecular life sciences : CMLS》2009,66(9):1580-1594
Digoxin and ouabain are steroid drugs that inhibit the Na+/K+-ATPase, and are widely used in the treatment of heart diseases. They may also have additional effects, such as on metabolism
of steroid hormones, although until now no evidence has been provided about the effects of these cardioactive glycosides on
the synthesis of cholesterol. Here we report that digoxin and ouabain increased the synthesis of cholesterol in human liver
HepG2 cells, enhancing the activity and the expression of the
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), the rate-limiting enzyme of the cholesterol synthesis. This effect
was mediated by the binding of the sterol regulatory element binding protein-2 (SREBP-2) to the HMGCR promoter, and was lost
in cells silenced for SREBP-2 or loaded with increasing amounts of cholesterol. Digoxin and ouabain competed with cholesterol
for binding to the SREBP-cleavage-activating protein, and are critical regulators of cholesterol synthesis in human liver
cells.
Received 10 January 2009; received after revision 11 February 2009; accepted 6 March 2009 相似文献
89.
N. Asano 《Cellular and molecular life sciences : CMLS》2009,66(9):1479-1492
A large number of compounds mimicking the structures of monosaccharides or oligosaccharides have been discovered from natural
sources. Such sugar mimics inhibit carbohydrate-degrading enzymes because of a structural resemblance to the sugar moiety
of the natural substrate. Carbohydrate-degrading enzymes are involved in a wide range of important biological processes, such
as intestinal digestion, posttranslational processing of the sugar chain of glycoproteins, their quality control mechanisms,
lysosomal catabolism of glycoconjugates, and some viral infections. It has now been realized that inhibitors of the enzymes
have enormous therapeutic potential in diabetes and lysosomal storage disorders. In this review, the general bioactivity,
current applications, and the prospects for new therapeutic applications are described.
Received 27 August 2008; received after revision 08 November 2008; accepted 03 December 2008 相似文献
90.
Wolfs JL Comfurius P Bekers O Zwaal RF Balasubramanian K Schroit AJ Lindhout T Bevers EM 《Cellular and molecular life sciences : CMLS》2009,66(2):314-323
The exposure of phosphatidylserine (PS) at the cell surface plays a critical role in blood coagulation and serves as a macrophage
recognition moiety for the engulfment of apoptotic cells. Previous observations have shown that a high extracellular [K+] and selective K+ channel blockers inhibit PS exposure in platelets and erythrocytes. Here we show that the rate of PS exposure in erythrocytes
decreases by ~50% when the intracellular [K+] increases from 0 to physiological concentrations. Using resealed erythrocyte membranes, we further show that lipid scrambling
is inducible by raising the intracellular [Ca2+] and that K+ ions have a direct inhibitory effect on this process. Lipid scrambling in resealed ghosts occurs in the absence of cell shrinkage
and microvesicle formation, processes that are generally attributed to Ca2+-induced lipid scrambling in intact erythrocytes. Thus, opening of Ca2+-sensitive K+ channels causes loss of intracellular K+ that results in reduced intrinsic inhibitory effect of these ions on scramblase activity.
Received 11 September 2008; received after revision 17 October 2008; accepted 27 October 2008 相似文献