液体钡镉锌复合稳定剂的研制

利用环烷酸、C_(7～9)脂肪酸的混合酸为原料,以亚磷酸三苯酯为螯合剂,采用沉淀法制备液体钡镉锌复合稳定剂,操作稳定,原料成本低,产品性能良好,是一条可行的工艺路线。     

灰数运算的几个基本问题

提出了灰数Ｏ与灰数１的概念，证明了它们具有许多类似于通常数Ｏ和１的性质、同时引进了灰数的绝对值，并对其主要性质作了研究，得到了有关灰数的绝对值的若干不等式．     

江苏省工业经济区划的研究

合理的工业经济区划，可使工业经济发展在空间上优化组合、合理配置，适应工业生产专业化、商品化和社会化的要求．本文运用社会物理学的基本原理，提出了工业经济区划的吸力模型．并将该模型应用于江苏省工业经济区划．订算结果表明，该工业经济区划的吸力模型，能合理地确定工业经济区．     

电位滴定在憎液胶体表面电荷密度研究中的应用

首先讨论了进行电位滴定实验的时候,逐次加入的滴定剂中决定电位离子的数量与被分析憎液胶体分散相粒子表面电荷密度之间的定量关系式,比较了文献中几种不同的零电点的测定方法,进而肯定了其中盐滴定法的可行性.然后,文章介绍了滴定过程中,不溶于水的氧化物或含氧氢氧化物胶体分散相与电解质溶液之间的慢速质子迁移现象,介绍了这一过程的机理以及它对从电位滴定得到的表面电荷密度σ_0值的影响,提出防止这一影响,区分慢速质子迁移与表面电离、表面络合反应对表面电荷的贡献,研究表面吸附机理的实验方法.     

根据惰性气体含量计算深层地下水的形成温度

惰性气体在地下水中的溶解量主要取决于水温和气体分压.而且溶解度在常见的水温范围内是水温的单调函数.因此,当深层地下水系统处于封闭状态,系统中不存在蜕变成因的惰性气体源时,可将溶解的惰性气体作为指示地下水形成温度的天然示踪剂.     

TiSiW12O40／TiO2催化合成邻苯二甲酸二辛酯

首次合成了非均相固载型杂多酸盐催化剂ＴｉＳｉＷ１２Ｏ４０／ＴｉＯ２，并用ＩＲ、ＵＶ、ＸＲＤ对其催化剂进行了表征。研究了该催化剂在合成ＤＯＰ中的催化作用。实验表明，在合成ＤＯＰ的酯化反应中，ＴｉＳｉＷ１２Ｏ４０／ＴｉＯ２具有极高的催化活性和选择性。     

脲系磷化合物的研究(Ⅱ)——N-(0,0-二烷基磷酰基)-N''-苯甲酰基脲的合成和性质

本文报导了8种新的N-(O.O一二烷基磷酰基)一N'一苯甲酰基脲的合成和波谱性质,通过对它们的'H-NMR的研究发现,这些目标化合物Jpll_a与烷基(?)(Taft constant)是线性关系。     

Compensatory caspase activation in MPP+-induced cell death in dopaminergic neurons

Many have hypothesized that cell death in Parkinsons disease is via apoptosis and, specifically, by the mitochondrial-mediated apoptotic pathway. We tested this hypothesis using a mouse dopaminergic cell line of mesencephalic origin, MN9D, challenged with the Parkinsonism-causing neurotoxin MPP⁺ (1-methyl-4-phenylpyridinium ion). Apoptosis was the main mode of cell death when the cells were subjected to MPP⁺ treatment under serum-free conditions for 24 h. Caspase-3 and caspase-9, however, were not activated, thus indicating the existence of alternate or compensatory cell death pathway(s) in dopaminergic neuronal cells. Using caspase inhibitors, we demonstrated that these pathways involve caspase-2, –8, –6 and –7. A time-course study indicated that activation of caspase-2 and –8 occurred upstream of caspase-6 and caspase-7. Upon MPP⁺ challenge, the apoptosis-inducing factor was translocated from the mitochondria into the MN9D cytosol and nucleus. These results suggest the existence of alternative apoptotic pathways in dopaminergic neurons.Received 20 September 2004; received after revision 5 November 2004; accepted 22 November 2004     

相对论性量子场反常维度与动量空间维度——纪念爱因斯坦《相对论》诞生百周年

 量子场中的奇异性(发散困难)被量子场反常维度C_B(g_R,e_R)与D=D₀-ε(D₀=4)中ε参数所控制,C_B(g_R,e_R)与ε可以相互替换.C_B(g_R)(QCD)的渐进自由被实验√S=30~1 800 GeV所证实.强相互作用的电荷依赖为C_B(g_R,±)=C_B(g_R,0)[1+be_R/g_R]²(b≤1).非线性相互作用改变了量子场的维度与量子场的拓扑不变性.     

BICP0 and its RING finger domain act as ubiquitin E3 ligases <Emphasis Type="Italic">in vitro</Emphasis>

Bovine infected-cell protein 0 (BICP0) encoded by bovine herpes virus 1 (BHV-1) immediate early gene is necessary for efficient productive infection, in a large part,because it activates all 3 classes of BHV-1 genes. It also has the ability to efficiently transactivate promoters that are not derived from BHV-1. To investigate the mechanism by which BICP0 achieves these effects, we expressed and purified BICP0 and its different mutants in E. coil In vitro assays showed that both full-length BICP0 and its isolated RING finger domain induce the accumulation of polyubiquitin chains. Mutations within the RING finger region that abolish the in vitro ubiquitination activity also cause severe reductions in BICP0 activity in other assays. Based on these, we conclude that BICP0 has the potential to act as an E3 ubiquitin ligase during viral infection and its RING finger domain is necessary for this function. These strongly support the hypothesis that BICPO might influence virus infection through its ability to interact with the ubiquitin-proteasome pathway.