C~3I系统理论评述

本文综述了C~3I系统研究中的主要问题与现状,讨论了该系统的建模、效能分析以及影响理论研究的几个因素,并对未来C~3I系统理论的主要问题、难点以及解决手段等进行了探讨。     

Changes in glycosaminoglycan sulfation and protein kinase C subcellular distribution during differentiation of the human colon tumor cell line Caco-2

Summary During the spontaneous differentiation (day 5 to day 15 of the culture) of Caco-2 cells, the sulfation of cell layer glycosaminoglycans increased, whereas protein kinase C activity was concomitantly redistributed from the membrane to the cytosol. The protein kinase C activators, 4-phorbol 12-myristate, 13-acetate and 1,2-dioctanoyl-glycerol inhibited glycosaminoglycan sulfation. By contrast, 4-phorbol 12, 13 didecanoate was ineffective.These results suggest that membrane-bound PKC may exert a modulatory effect on glycosaminoglycan sulfation, and this effect is gradually attenuated as Caco-2 cell differentiation progresses.     

Effect of protein kinase C activation and depletion on insulin stimulation of glycogen synthesis in cultured hepatoma cells

Summary Insulin stimulation of glycogen synthesis was nearly abolished in hepatoma cells shortly treated with 4 ß-phorbol 12 \-myristate, 13 -acetate (protein kinase C activation) but remained unmodified in cells chronically treated with the phorbol ester (protein kinase C depletion). Thus, although exogenous activation of protein kinase C results in an inhibition of insulin action, protein kinase C depletion has no influence on this process. The results suggest that, in hepatoma cells, no endogenous activation of protein kinase C may occur in response to the signal triggered by insulin.     

一种防空C~3I系统的效能分析方法

本文讨论了一种评定C~3I系统效能的方法。这种方法是根据系统完成使命的能力和系统的内部结构两方面的分析来完成的。通过对IFFN系统的评定,对本方法进行了举例说明。     

Proopiomelanocortin expression in the skin during induced hair growth in mice

We demonstrate for the first time a hair cycle-dependent gene and protein expression of proopiomelanocortin in mouse skin in vivo. Northern blot detected POMC mRNA with an apparent size of 0.9 kb in anagen but not telogen skin. Western blot emphasized a specific protein of 30–33 kDa recognized by anti -endorphin in late but not early anagen or telogen skin. By immunocytochemistry, -endorphin antigen was localized in the sebaceous gland in a hair cycle dependent manner.     

Preferential excretion of glycated albumin in C57BL-Ks-J mice: Effects of diabetes

Urinary excretion of glycated albumin was quantitated in genetically hyperglycemic mice (C57BL-Ks-J, db/db mice), a model for non-insulin-dependent diabetes mellitus, and compared with their non-diabetic littermates. The data indicated a preferential excretion of glycated albumin in non-diabetic mice. This phenomenon of editing of glycated albumin is decreased significantly in diabetic mice. Quantitative measurements of overall excretion of glycated albumin suggested that the loss of editing in diabetic mice is due to the dilution of glycated albumin by the unmodified albumin which is excreted in large amounts in diabetic mice. Therefore, the loss of editing observed in this model resembled the one we characterized in insulin-dependent diabetic humans and a streptozotocin-diabetic rat model³.     

基于三级模式的信息系统设计的优化

指出了传统的C／S模式的缺陷，说明了基于三级(N级)模式设计的概念及采用该技术开发应用程序的优越性。在这个基础上着重讨论了运用三级(N级)模式开发应用程序时应该注意的问题，提出了一些设计使用中的建议。如任务分割、避免死锁、采用OO技术等，并给出了应用实例．     

用自定义C函数创建中文立体上弹式菜单

通过BIOS中断调用建立一组自定义C函数，在文本方式下，以任意背、前景色显示以矩形框修饰的窗口和以任意位置、背景、前景、字体、字型显示汉字，从而建立中文立体上弹式菜单，并给出了实现的源程序．     

分布式程序模式及其在保险信息系统中的应用

对分布式网络体系统结构的发展过程进行了介绍和分析，然后结合保险信息系统，对其采用的分布式网络和分布式应用程序设计思路和发展阶段进行了分析，最后对保险信息系统的分布式应用趋势进行预测。     

基于CAN总线车辆底盘综合电子系统的虚拟仪表终端设计

从硬、软件两方面介绍虚拟仪表的设计方法.硬件采用嵌入式加固PC机,该机内的CAN控制器主要完成虚拟仪表的数据接收和转换功能;软件采用多任务操作系统———Windows为基本操作系统,以VisualC 为集成开发环境,在此基础上设计和开发虚拟仪表程序.