双氯芬酸钠联合黄体酮治疗肾绞痛疗效观察

目的观察双氯芬酸钠联合黄体酮治疗泌尿系统结石引起的肾绞痛的疗效。方法将泌尿系统结石引起的肾绞痛的患者随机分成观察组和对照组。观察组采用双氯芬酸钠注射液50mg,肌注及黄体酮注射液40mg,肌注。对照组采用哌替啶注射液75mg,肌注。观察用药后60min时的疗效。结果观察组和对照组的显效率和总有效率分别为58.6%,96.6%和57.5%,95.4%,观察组疗效略高于对照组,但无统计学差异,P〉0.05。结论双氯芬酸钠联合黄体酮治疗泌尿系统结石引起的肾绞痛疗效好,且无成隐性,值得临床推广。     

一次性VB1半导体传感器的研究

报道了一种以四苯硼钠为活性物质的一次性VB1半导体传感器.其Nernst响应线性范围为1.0×10-1～1.0×10-5 mol/L;斜率为29 mV/pC;检测下限为2.0×10-6 mol/L.该传感器具有全固化、易微型化和多功能化等优点,可用于测定人尿中VB1的排出量及生物和医学方面的一次性使用.     

阴离子表面活性剂存在下氯化血红素催化性能的研究

研究了十二烷基苯磺酸钠(SDBS)存在下氯化血红素(Hemin)类似过氧化物酶的新型催化活性。在pH 8.0～8.9氨性缓冲介质中,Hemin催化溶解氧氧化溴邻苯三酚红的褪色反应。在SDBS和30%乙醇的增效作用下,催化体系服从Michaelis-Menten方程。用Lineweaver-Burk作图法求得米氏常数、催化常数和专一性常数分别为3.7×10^-5mol/L, 0.64s^-1和1.7×10⁴L·mol^-1·s^-1。对机理进行了讨论。利用该催化体系,用反应平衡法和动力学法均可分光光度定量Hemin, 线性范围为2.0×10^-8～6.0×10^-7mol/L,检测限为2.5×10^-9mol/L。     

Nitric oxide produced by cumulus cells stimulates maturation of mouse oocytes

The effect of sodium nitroprusside (SNP), a donor of nitric oxide, on meiotic maturation of mouse oocytes was studied by injecting N^w-nitro-L-arginine methyl ester (L-NAME) intra-peritoneal (ip), a nitric oxide synthase inhibitor, or culturing oocytes in the medium supplemented with L-NAME or hypoxanthine (HX) to arrest the spontaneous oocyte maturation in vitro. The results showed that the inhibitory effect of L-NAME by injecting 10 mg/kg ip on extrusion of the first polar body only could be reversed by injecting 2.5 mg/kg SNP with L-NAME simultaneously (P < 0.05). Half an hour later ten mice died when given 10 mg/kg SNP ip. The treatment of some concentrations of SNP (10^–7, 10^–6, 10^–5mol/L) significantly stimulated meiotic maturation to metaphase Ⅱ stages in cumulus enclosed oocytes in the presence of HX. However, other concentrations of SNP (10^–8, 10^–4, 10^–3 mol/L) had no effect on HX-arrested oocyte meiotic maturation. The optimal concentration of SNP on CEOs had no effect on DOs. The dose of 10^–3 mol/LL-NAME demonstrated a significant suppression in formation of PB₁, but not in GVBD. This inhibition was reversed by the addition of SNP. These results indicated that the physiological levels of NO produced by cumulus cells could stimulate meiotic maturation of mouse oocytes both in vivo and in vitro.     

钠钨青铜的低温水热合成的研究

该文采用低温水热合成法制备出x约为 0 .4的导电材料钠钨青铜晶体。通过条件实验确定了水热法制备钠钨青铜的较佳工艺条件 ,提出了目标产物提纯方法。用便宜、易得的KBH4 代替NaBH4 作了探索实验 ,得到了与目标产物接近的产品。红外光谱表明产物具有良好的红外光吸收性能。电阻率的测定结果表明目标产物具有良好的导电性     

Regulation of the retinal interphotoreceptor matrix Na by the retinal pigment epithelium during the light response

We examined the rabbit retinal pigment epithelium (RPE) for Na transport properties which would allow it to buffer undesirable changes in Na concentrations in the interphotoreceptor matrix (IPM) during light and dark cycles. The RPE is selectivity permeable to sodium. Open and short circuit transport studies with RPE indicate a circulating (choroid to retina and back) Na current which does not compromise the electrical integrity of the blood brain barrier but together with the Na permeselectivity is of sufficient magnitude to buffer both upwards and downwards movements of IPM [Na] during light or dark responses.     

SJY高爆速液体炸药中硝酸肼含量的紫外分光光度测定法

SJY高爆速液体炸药的各组份中,只有硝酸肼在303nm处有吸收?,因它的克分子吸光系数小,故可以用于测定高含量的硝酸盐。从而建立了SJY高爆速液体炸药中硝酸肼含量的紫外分光光度测定法。     

流动注射分析法测定保险粉(简报)

本文讨论应用流动注射分析结合光度测定进行低亚硫酸钠(保险粉)的测试。所采用的载流为K_2Cr_2O_710g溶解于111.8×10~(-1)mol/l的H_2SO_4溶液,流速为2.8ml/min。在590nm处测其吸光度。试样通过填有海绵的玻璃管直接抽吸入FIA仪器进行测定。与传统的碘量法相比,其相对误差小于1.5％。数据表明有良好的重现性。     

盐水杂质对胺法制碱碳化及结晶的影响

在搅拌鼓泡反应器中进行胺法制碱的碳化试验,探讨了盐水中其它物质:CaCl_2、MgCl_2、KCl、Na_2SO_4、CaCO_3、MgCO_3对NaCl溶液碳化的影响,其碳化能力顺序为:CaCl_2>MgCl_2>NaCl>KCl。考察了温度对海盐溶液与纯氯化钠溶液碳化和重碱粒度的影响,讨论了硅油消除液液两相界面气泡的可能性,从而提出了胺法制碱中必须去除Ca~(2+)和Mg~(2+)。     

一种提高苄叉丙酮合成肉桂酸的新方法

苄叉丙酮经次氯酸钠卤化反应为肉桂酸钠,酸化前用还原剂Na_2SO_3或NaHSO_3除去过量的次氯酸钠,产率达78％,纯度达95％,并用分析鉴定结果表明使用还原剂提高产率和纯度的理论依据。