渣油加氢微膨胀床反应器中的气液流动状态及床层膨胀率

在常温常压下用模拟渣油和模拟氢气近似模拟了微膨胀床渣油加氢处理反应器内的气液流动状态,考察了催化剂粒径和堆密度、虚拟气液流速以及催化剂装填高度对催化剂床层膨胀率的影响。实验结果表明:大粒径、低堆密度的催化剂床层膨胀率较高;虚拟气速与床层膨胀率关系曲线上存在拐点,拐点值随催化剂装填高度增加而增大;虚拟液体流速对催化剂床层膨胀率影响较小;在工业操作条件下,微膨胀床渣油加氢处理反应器的催化剂床层膨胀率小于10%;催化剂装填高度对床层膨胀率有明显的影响,催化剂装填量较大时,需要采用较高的气油比才能保证催化剂床层处于微膨胀状态。     

(2+1)维色散长波方程的双周期解

借助计算机代数操作系统,引入Jacob ian椭圆函数负幂次展开的方法,求解(2+1)维色散长波方程,得到一系列新的双周期解。     

双大Reynolds数问题的混合方法

讨论双大Reynolds数问题,首先将解析解分解为光滑部分和奇性部分,对这两部分都做了上界估计;然后将解析解进行2阶渐近展开;最后提出混合算法．混合算法的主要思想是引入过渡点将区域分为粗网格区域和细网格区域,在这些网格区域采用等步长．在细网格区域采用有限元法,在粗网格区域采用迎风差分格式．混合算法结合了渐近解、数值解和BVT法的优势,是一个实用、有效的算法。     

Mating behaviour and maternal care in the tropical savanna funnel-web spider Aglaoctenus lagotis Holmberg (Araneae: Lycosidae)

Despite their abundance and diversity, Neotropical spiders have been the subject of relatively few studies of behavioural ecology. The sexual behaviour and maternal care of the spider Aglaoctenus lagotis (Lycosidae) is described here. We performed experimental manipulations to test the hypothesis that males are attracted by female cues in the web. Two predictions were tested: (a) webs used by a virgin female will attract more males than webs used by an inseminated female; (b) the main cue in the web is chemical, so webs recently used by virgin females will attract more males than those that are not recently used. Additionally, we tested the hypothesis that maternal care increases offspring survivorship. Results showed that males are attracted by recently used webs (z = 0.0015; p = 0.037; z-test) and webs of virgin females (z = 0.041; p = 0.036, z-test). Male sexual behaviour presented three different categories: court, pre-mate and mate. After the mating, the females built a cocoon that was transported adhered to the spinnerets and held by the last pair of legs. After the hatching of the eggs, the young migrated to the dorsal region of the mother's body for 5 days. During maternal care the mother eliminates a yellowish drop from its oral cavity, which is collected by the young. During the development of the young until adulthood, the offspring that have their mother present in the first stages of life have greater survival compared with those without maternal care. Our results make it possible to perform comparative analyses between a South American Lycosidae species and other species distributed worldwide.     

中国的出口扩张是否影响了健康?——基于Grossman模型的拓展分析

在全球经济复苏乏力的背景下,"逆全球化"浪潮正以不可思议的速度席卷全球,并顺势引导着我们重新审视"全球化"的益处及其隐形成本.鉴于目前并没有相关文献从理论上探讨出口扩张对健康的影响,本文以中国改革开放以来迅猛的出口扩张为背景进行了首次探索.本文构建了一个工人们与其雇主讨价还价的企业出口模型框架.厂商依据利润最大化原理选择最优的资本、劳动和原材料的投入之后,每个工人也会选择"最优的工作努力程度"使得努力的边际收益等于努力的边际成本.然后.依据Grossman健康需求模型.本文系统地探讨了由外生性原因引致的出口扩张影响工人健康的五个路径,包括工作强度,工资率,收入差距,公共服务和环境污染.最后,依据文章结论提出相应的政策建议.     

Wick类型随机广义Kdv-MKdv方程的精确解

通过埃尔米特变换将Wick类型的随机广义Kdv MKdv方程变成广义系数Kdv MKdv方程, 利用截断展开法求出广义系数Kdv MKdv方程的精确解, 并通过埃尔米特逆变换得到了随机广义Kdv MKdv方程的精确解.     

一类奇摄动初值问题解的渐近展开

用边界函数法研究了一类奇摄动初值问题解的渐近展开问题,证明了解的存在惟一性,并给出该解的渐近分析.     

复杂规划问题的证据合成寻优方法及在电源规划中的应用

模拟人类寻优思维,将下降可行方向推广为证据合成网络,构造了证据合成算法和相应交互式寻优方法,并应用于电源规划问题     

Expansion of amino acid homo-sequences in proteins: Insights into the role of amino acid homo-polymers and of the protein context in aggregation

Expansion of amino acid homo-sequences, such as polyglutamines or polyalanines, in proteins has been directly implicated in various degenerative diseases through a mechanism of protein misfolding and aggregation. However, it is still unclear how the nature of the expansion and the protein context influence the tendency of a protein to aggregate. Here, we have addressed these questions using spinocerebellar ataxia type-3 (ATX3) protein, the best characterised of the polyglutamine proteins, chosen as a model system. Using a transfected mammalian cell line, we demonstrate that ATX3 aggregation is noticeably reduced by deletion or replacement of regions other than the polyglutamine tract. The nature of the amino acid homo-sequences also has a strong influence on aggregation. From our studies, we draw general conclusions on the effect of the protein architecture and of the amino acid homo-sequence on pathology. Received 3 March 2006; received after revision 19 April 2006; accepted 22 May 2006     

Huntington’s disease: from huntingtin function and dysfunction to therapeutic strategies

Huntington’s disease (HD) is a neurodegenerative disorder that usually starts in middle age and is characterized by involuntary movements (chorea), personality changes and dementia, leading to death within 10–20 years. The defective gene in HD contains a trinucleotide CAG repeat expansion within its coding region that expresses a polyglutamine repeat in the protein huntingtin. Together with the characteristic formation of aggregates in HD, aberrant protein interactions and several post-translational modifications affect huntingtin during disease progression and lead to the dysfunction and death of selective neurons in the brains of patients. The exact molecular mechanisms by which mutant huntingtin induces cell death are not completely understood but may involve the gain of new toxic functions and the loss of the beneficial properties of huntingtin. This review focuses on the cellular functions in which huntingtin is involved and how a better understanding of pathogenic pathways can lead to new therapeutic approaches. Received 24 May 2006; received after revision 5 July 2006; accepted 23 August 2006