Ethanol and the benzodiazepine-GABA receptor-ionophore complex

Summary Ethanol has a pharmacological profile similar to that of classes of drugs like benzodiazepines and barbiturates, which enhance GABAergic transmission in the mammalian CNS. Several lines of behavioral, electrophysiological and biochemical studies suggest that ethanol may bring about most of its effects by enhancing GABAergic transmission. Recently, ethanol at relevant pharmacological concentrations has been shown to enhance GABA-induced³⁶Cl-fluxes in cultured spinal cord neurons, synaptoneurosomes and microsacs. These enhancing effects of ethanol were blocked by GABA antagonists. Ro15-4513, an azido analogue of classical BZ antagonist Ro15-1788, reversed most of the behavioral effects of ethanol and other effects involving³⁶Cl-flux studies. The studies summarized below indicate that most of the pharmacological effects of ethanol can be related to its effects on GABAergic transmission.     

一种适合于低空无线信道的改进SC FDE技术

目前国内外对于低空无线信道的报道较少, 尚未建立统一的模型, 而由于多径时延和多普勒频移的影响, 传统的单载波频域均衡(SC FDE)技术在该信道下的传输性能较差. 本文在航空信道建模的基础上, 分析了不同场景下低空无线信道的传输特性, 建立了相应的信道模型. 为了在低空无线信道下获得良好的传输性能, 提出了一种基于Turbo编码和最优信号子空间(OSS)理论的改进SC FDE技术. 仿真结果表明, 该技术能很好地适应低空无线信道的特性, 可以在低信噪比(SNR)条件下获得较低的误码率(BER), 从而提升了通信系统在该信道下的传输性能.     

磁流变液可控多流道悬置隔振性能仿真分析

设计一种动刚度和阻尼可调的磁流变液可控多流道悬置.首先,建立多惯性通道液压悬置模型,数值仿真不同的流道数量对悬置动刚度和滞后角的影响;然后,建立磁流变液可控多流道悬置模型,通过实验验证可控多流道可以控制流道的开闭;最后,分析磁流变液可控多流道悬置不同流道开闭的动态特性变化.结果表明:对不同的流道分别施加磁场作用可使悬置的动刚度、阻尼可调和力的传递率最小;已知激励频率,根据可控区域实时控制流道数量,可获得最佳隔振性能.     

浅析灌区节水灌溉

阐述了在目前水资源严重匮乏的形势下大力推广节水灌溉的重要性和必要性,指出加强灌区硬件设施的改造和促进人们用水观念的转变是实现节水灌溉的有效途径。     

频率色散移动信道的仿真模型分析

通过分析频率色散移动信道的衰落特性，分别对该信道在快衰落特性，慢衰落特性以及同时考虑快衰落和慢衰落这三种情况下建立了数学模型和计算机仿真模型，并对计算机仿真结果进行了分析，提出了相应结论。     

OFDM系统在短波信道上的线性均衡方法

由于短波信道CHF的时变和多径,使OFDM信号的正交性受到损失(产生子载波间干扰ICI),从而导致了码间串扰(ISI),误码底板上升,并且随着信道的多普勒频率的增加而增加。针对这种情况,提出了一种简单的频域均衡方法。这种均衡方法假设:在一个OFDM块期间,信道的冲激响应(CIR)是线性变化的,而常规的单抽头频域均衡器对频率选择性多径衰落信道的补偿是假定在一个FFT块期间信道是静态的。当相对多普勒频率在范围(1.0005.0相似文献   

A novel pattern of fast calcium oscillations points to calcium and electrical activity cross-talk in rat chromaffin cells

Slow oscillations of cytosolic calcium ion concentration – – typically originate from release by intracellular stores, but in some cell types can be triggered and sustained by Ca²⁺ influx as well. In this study we simultaneously monitored changes in and in the electrical activity of the cell membrane by combining indo-1 and patch-clamp measurements in single rat chromaffin cells. By this approach we observed a novel type of spontaneous oscillations, much faster than those previously described in these cells. These oscillations are triggered and sustained by complex electrical activity (slow action potentials and spike bursts), require Ca²⁺ influx and do not involve release from intracellular stores. The possible physiological implications of this new pathway of intracellular signalling are discussed.Received 30 July 2004; received after revision 14 October 2004; accepted 1 November 2004     

NH2自由基电子基态及激发态解离通道的静力学分析

本文利用原子分子反应静力学的基本原理,研究了NH2自由基体系的可能解离通道,得到了NH2自由基电子基态2B1及第一激发态2A1合理的解离通道。     

Pragmatic Approach to Adaptive Turbo Coded Modulation

This paper presents a pragmatic adaptive scheme for TuCM over slowly fading channels. The adaptive scheme employs a single turbo coded modulator composed of a variable-rate turbo encoder and a variable-rate variable-power MQAM for all fading regions, so it has an acceptable complexity to implement. The optimal adaptive TuCM scheme is determined subject to various system constraints. Simulations have been performed to measure the performance of the scheme for different parameters. It is shown that adopting both the turbo coded modulator and the transmit power achieves a performance within 2.5 dB of the fading channel capacity.