云南中、小病险水库病害机理及除险加固对策

结合云南省部分病险水库的除险加固工作,分析了病害隐患存在的机理和原因,提出除险加固中应采取的对策和措施,为更好的完成中、小型病险水库的除险加固工作提供参考。     

基于网络方法的疾病基因预测算法分析

目的 分析基于各类生物网络的复杂疾病致病基因预测算法,总结其优势及不足之处,提出改进思路及未来的研究方向。方法 深入分析当前基于网络的疾病基因预测算法原理,包括不同生物网络的构建、算法原理的基本假设、3个代表性算法及基于其发展出的最新方法。结果与结论 分析发现当前算法存在的3个不足并指出解决此不足的2种思路。     

Relationship between the specific surface area of rust and the electrochemical behavior of rusted steel in a wet-dry acid corrosion environment

The relationship between the specific surface area (SSA) of rust and the electrochemical behavior of rusted steel under wet-dry acid corrosion conditions was investigated. The results showed that the corrosion current density first increased and then decreased with increasing SSA of the rust during the corrosion process. The structure of the rust changed from single-layer to double-layer, and the γ-FeOOH content decreased in the inner layer of the rust with increasing corrosion time; by contrast, the γ-FeOOH content in the outer layer was constant. When the SSA of the rust was lower than the critical SSA corresponding to the relative humidity during the drying period, condensed water in the micropores of the rust could evaporate, which prompted the diffusion of O₂ into the rust and the following formation process of γ-FeOOH, leading to an increase of corrosion current density with increasing corrosion time. However, when the SSA of the rust reached or exceeded the critical SSA, condensate water in the micro-pores of the inner layer of the rust could not evaporate which inhibited the diffusion of O₂ and decreased the γ-FeOOH content in the inner rust, leading to a decrease of corrosion current density with increasing corrosion time.     

基于相空间重构和支持向量机的小麦条锈病预测方法

小麦条锈病预测对小麦灾害的预防和控制具有十分重要的意义.本文使用相空间重构和最小二乘支持向量机相结合的方法对成都市小麦条锈病发病率进行预测.实验中使用成都地区的气象数据作为模型的输入参数,发病率作为模型的输出参数,对20例发病病例样本进行预测,得到了比较好的预测效果.实验中还与简单最小二乘支持向量机预测结果作了对比,结果表明,相空间重构和最小二乘支持向量机结合的模型预测准确率明显高于简单最小二乘支持向量机,因此本模型对小麦条锈病预测是十分有效的.     

保护医学——一个正在兴起的交叉学科

保护医学作为一门新兴的交叉学科已受到广泛瞩目。保护医学涉及人类健康、动物健康和生态系统健康3个层面,它们构成有机的整体,相互影响,相互作用,缺一不可。保护医学研究的最终目标是实现生态的健康,这是保证包括人类在内的生命健康的根本前提。它强调健康与生态、环境之间的联系,体现了多学科的交叉,如人类健康和公共卫生、流行病学、兽医学、毒物学、生态学和保护生物学等,而且其研究方法也体现出多学科交叉的特点。     

Endogenously generated amyloid β increases membrane fluidity in neural 2a cells

The effect of endogenously generated amyloid β on membrane fluidity was investigated in Neural 2a cells stably expressing Swedish mutant amyloid precursor protein (APPswe). Membrane fluidity was studied by fluorescence polarizability using 1,6-Diphenyl-1,3,5-Hexatriene (DPH) as the fluorescence probe. It was found that the membrane fluidity in APPswe cells was significantly higher than that in its wild type counterparts. Alleviating the effect of amyloid β either by γ secretase activity inhibition or by amy...     

疾病基因网络的二分图投影分析

介绍了一种可揭示同一集合内部结点相互关系的二分网络投影方法,并运用此方法对基因疾病二分网络图做研究.通过遗传性疾病与致病基因的关联性来分析不同疾病之间隐含的相互关系,得出由相同的基因变异所引起的各种不同疾病之间存在着或多或少的联系,这些疾病比起毫无联系的疾病,其相互引发的概率也要大得多.此结论使我们能够更清楚地认识到遗传性疾病的发病机制,对疾病预防以及医疗诊断都有一定的参考价值.     

临汾高速公路沥青路面早期病害与处治

临汾高速公路路面早期病害现象有：裂缝、水破坏、松散、唧浆、坑槽、车辙等,这些病害直接影响了车辆的运行,导致行驶质量下降。文章针对临汾高速公路路面早期病害的成因进行了分析,提出了相应的处治对策。     

健身气功·五禽戏对高脂血症患者细胞黏附分子及血脂水平的影响

探讨健身气功·五禽戏锻炼对高甘油三酯血症（HTG）患者血浆细胞黏附分子及血脂水平的影响,采用随机选择HTG患者62例,随机分为运动组（实验组）和对照组,观察患者实验前后血浆可溶性细胞间黏附分子-1（siCAM-1）和可溶性血管细胞间黏附分子-1（sVCAM-1）及血脂相关指标浓度的变化。结果显示：经6个月健身气功·五禽戏运动锻炼后,实验组slCAM-1、sVCAM-1、Ps、Fig、TG、TC和LDL—C水平明显低于对照组,HDL—C水平明显高于对照组,其差异均有显著性（P〈0．05或0．01）．认为健身气功·五禽戏运动锻炼具有良好的调节血脂异常的作用,并可降低高甘油三酯血症患者细胞黏附分子水平．