论无锡市欣丰电容器厂的优势、劣势以及在企业宏观与微观环境中的威胁与机会

文章从企业组织,员工队伍,经营业务领域以及经营发展轨迹出发,以企业经营所处的宏观环境与微观环境为切入点,对企业在竞争中的优势与劣势,以及企业在经营与发展所处环境中面临的机会与威胁进行了分析。     

Specific anti-tumor effect induced by attenuated Salmonella typhimurium vaccine expressing extracellular region of vascular endothelial growth factor receptor 2

The purposes of this research were to study the stable expression of exogenous gene encoding therapeutic protein in attenuated Salmonella typhimurium, observe the metabolism of oral gene vaccine carried by attenuated Salmonella typhimurium in BALB/c mouse, and investigate the feasibility of prevention and treatment of tumors by the recombinant bacteria. Recombinant plasmid pcDNA3.1 VEGFR2(n1-7) was transformed into competent attenuated Salmonella typhimurium SL3261 to develop oral DNA vaccine SL3261-pcDNA3.1 VEGFR2(n1-7). To observe whether the exogenous gene can be expressed in the recombinant bacteria, PCR was performed to amplify the CMV promoter of the eukaryotic expression vector as the proof of stable expression of exogenous protein; transmission elec- tron microscopy (TEM) was applied to observe the morphology of the recombinant bacteria to confirm that the exogenous gene has no impact on the growth of the bacteria, and then BALB/c mice were immunized with the gene vaccine. After inoculation of the gene vaccine, the recombinant bacteria SL3261 could be detected in the tissues such as small intestine, colon, liver and spleen. And then, mice in each group were challenged with tumor cells. The results of animal experiment showed that tumor growth of the mice in experimental group was inhibited and survival time of immunized mice was prolonged compared with control groups. A higher lymphocyte infiltration in tumors from animals treated with DNA vaccine was observed. Immunohistochemical analysis of tumor samples revealed an en- hanced accumulation of CD8 cytotoxic T lymphocytes, as well as an increase in CD4 cells in the tumors of animals treated with the oral gene vaccine compared to tumors from control group mice. Ultrastructure of the tumor tissue showed that tumor cells in the samples of the immunized mice were well-differentiated. Our research confirmed that the exogenous gene can be stably expressed in the attenuated Salmonella typhimurium and has no impact on the growth of the recombinant bacteria; the exogenous gene can de delivered to the host by attenuated Salmonella typhimurium to produce anti-tumor effect with no obvious cytotoxity to the host. In this study, it is established that attenuated Salmonella typhimurium could be used as a vector for oral gene vaccine, and our study provided a theoretical basis for the body distribution and the metabolism of the recombinant bacteria. This strategy may provide a simple, safe and effective way for the prevention and treatment of tumors.     

Comparison of Drought-Resistance about Three Wild Rocky-Grasses

In this experiment, using the methods of drought-stress in the pot and PEG simulative drought-stress, three native rocky-slope grasses Pogonatherum panideum（Lam.） Hack, Erioophorum comosum nees and Cynodon dactylon cultivated in the pots were selected as materials to study their drought-resistance by analyzing the indexes such as the leaf area index, the drying roots accumulation, the holding water ability of leaf, the relative conductance of leaf, the soluble protein, chlorophyll. At the same time, by comparing with membership function value of each index, the order of each grass drought-resistance was decided. The results showed that the drought-resistance of Erioophorum comosum nees was stronger than Cynodon dactylon and drought-resistance of Cynodon dactylon was stronger than Pogonatherum panideum （Lam.） Hack. The purpose of the experimental results was to find theoretical foundations for selecting and cultivating native protecting-slope vegetations to adapt to rocky slopes.     

我国存货准则与IAS2的比较与思考

我国已经颁布了新的存货准则,并于今年年初开始实施,这对于进一步规范企业存货的确认、计量和披露,提高会计信息的相关性和可靠性,完善我国会计准则体系,推动我国证券市场乃至整个社会主义市场经济的发展,将起到积极的作用.     

Eph受体家族和Ephrin-A5在NSCLCs中上调表达及其临床意义

采用荧光实时定量PCR的方法在48个非小细胞肺癌组织以及配对的正常肺组织中检测Eph/ephrin 基因的mRNA水平.发现肺癌组织中EphB4, EphB3 和 ephrin-A5的表达水平与配对的正常肺组织相比分别上调了60%,81%和65%,并具有显著的统计学差异. 而且,统计学分析发现ephrin-A5的表达水平与肿瘤分型、转移、性别、吸烟以及诊断年龄等临床病理学参数之间存在显著的相关性.此外,EphA2的表达水平与肿瘤大小、家族遗传史以及诊断年龄之间也存在显著的相关性.总之,这些结果提示EphB4, EphA2, EphB3 和ephrin-A5 在肺癌的发生和发展过程中可能以一种单独或者协同的形式发挥作用.这些蛋白有可能成为研究和诊断肺癌的重要靶向基因.     

Effects of self evaluation on late ERP components

High-density event-related potentials (ERPs) were measured when participants were required to evaluate oneself, significant others (father and mother) and the most familiar public figures (Lei Feng and Jiang Qing) based on trait adjectives. There were three referential conditions and a non-referential control condition including self-evaluation (SE), significant other-evaluation (SOE), general other-evaluation (GOE), and semantic positivity-evaluation (SPE). The behavioral data showed that RTs to GOE condition were longer than the other three conditions. Scalp ERP analysis revealed that (1) SPE condition elicited a more negative N2 than SE condition, which was associated with inhibition of responses; (2) SE condition elicited a more positive P300 than SPE condition, which was an index of attention to self-relevant stimuli; (3) there was no difference on the amplitude and latency of P300 between SE and SOE conditions, which reflected that the concept of “self” included intimate others (e.g., father and mother) in Chinese culture.     

TPL企业强化TQM的途径研究

探讨TPL企业的服务质量特性及TQM内涵和评价指标体系，提出强化TPL企业TQM的主要途径：（1）确立科学的TPL企业质量观；（2）坚持不断地改进组织中每项工作的质量，深化注重企业质量管理的文化建设；（3）建立可精确地度量并向员工授权的有效TQM机制；（4）加大企业资源在TQM的战略性投入．     

反周期函数(0,P(I))三角插值

通过引进积分算子P(I),研究了反周期函数插值及反周期函数的2-周期(0,P(I))插值,得到了解存在的条件,并给出对应条件下解的显式.     

电子商务的应用及对企业的影响

简述了电子商务理论的演变过程及电子商务的应用形式,包括电子数据交换、网上营销、网络银行等。探讨了电子商务的应用使企业面临的历史变革,指出作为21世纪的一种基本商务形式,电子商务已经成为具有敏锐战略眼光企业家的选择。     

A NEW DESCRIPA NEW DESCRIPTOR OF AMINO ACIDS BASED ON THE THREEDIMENSIONAL VECTOR OF ATOMIC INTERACTION FIELD

QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (QSAR) IS A VERY IMPORTANT TOPIC FOR MANY SCIENTIFIC FIELDS AND CAN BE TERMED AS QUANTITATIVE SEQUENCE ACTIVITY MODELS(QSAM)[1] WHEN REFERRED TO THE RESEARCH ON RELATION- SHIPS BETWEEN STRUCTURES AND ACTIVITIES OF BIOLOGICAL MOLECULES, SUCH AS PROTEINS, AND NUCLEIC ACIDS. HOW- EVER, IT IS VERY DIFFICULT TO ESTABLISH A QSAM MODEL,…