论校办高新技术产业的意义和对策

本文论述了高等院校创办高新技术产业的意义、作用和有力条件,并针对一些问题提出了进一步发展校办高新技术产业的五项对策。     

秦皇岛旅游区系构成与系统发展

本文从秦皇岛各旅游区结构和功能特点出发，论述了秦皇岛旅游区系的构成状况并提出了系统发展的几个问题．     

一个正规定则及其推论

本文证明了亚纯函数的一个正规定则,它是montel定则的一般化,另外,我们给出它的一些应用。     

评岛尾永康的《中国化学史》

文章对于日本学者撰写的第一部《中国化学史》进行了分析评论，认为该书具有的主要特点是：（１）时代性，概括了直到１９９２年以前的最新研究成果；（２）严谨性，运用文献丰富，以求得出严密结论；（３）辩驳性，注意从不同见解的争论中进行阐述，自然得出结论；（４）社会性，注意把化学发展置于整个社会中考察，揭示深层动因；（５）比较性，注意把中国化学发展置于世界范围考察，体现中国的特点和作用；（６）形象性，运用相当丰富的图片进行叙述，具体、生动；（７）日本视野性，以日本学者特有的角度阐述中国化学发展，具有独到之处。文章还指出了该书一些需要改进和提高之处。     

An in situ zircon Hf isotopic,U-Pb age and trace element study of banded granulite xenolith from Hannuoba basalt： Tracking the early evolution of the lower crust in the North China craton

Backscattered electron images, in situ Hf isotopes, U-Pb ages and trace elements of zircons in a banded granulite xenolith from Hannuoba basalt have been studied. The results show that the banded granulite is a sample derived from the early lower crust of the North China craton. It is difficult to explain the petrogenesis of the xenolith with a single process. Abundant information on several processes, however, is contained in the granulite. These processes in-clude the addition of mantle material, crustal remelting, metamorphic differentiation and the delamination of early lower crust. About 80% of zircons studied yield ages of 1842 ±40 Ma, except few ages of 3097-2824 Ma and 2489-2447 Ma. The zircons with ages older than 2447 Ma have high εHf (up to +18.3) and high Hf model age (2.5-2.6 Ga), indicating that the primitive materials of the granulite were derived mainly from a depleted mantle source in late Archean. Most εhf of the zircons with early Proterozoic U-Pb age vary around zero, but two have     

Cloning and roles of goldfish maternal factor β-Catenin cDNA in embryonic development

Interaction between nucleus and cytoplasm has been focused in the field of animal embryonic development, in which study of maternal factors is required positively. β-Catenin, an important maternal factor in early embryogenesis, has been analyzed in its expression pattern and functions in this paper. We have cloned goldfish β-Catenin cDNA gene and compared it with zebrafish β-Catenin cDNA. High homology was found in cDNA and in amino acid sequences between them, 93% (2227/2384 bp) and 98.5% (768/780 aa) respectively. The expression pattern of β-Catenin by in situ hybridization and the roles of β-Catenin on embryonic development by co-injection of anti-sense RNA and reporter gene, EGFP have been investigated in the whole process of goldfish embryonic development. The results suggest that β-Catenin presents dynamic distribution, mainly locates at body axis, dorsal tissues, head and tail structures after being fertilized. The loss of β-Catenin activity would cause serious destruction of embryo in dorsal tissues and in anteroposterior axes, and leads embryos to die before larva get hatched.     

Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications

Apoptosis is a morphologically distinct form of cell death. It is executed and regulated by several groups of proteins. Bcl-2 family proteins are the main regulators of the apoptotic process acting either to inhibit or promote it. More than 20 members of the family have been identified so far and most have two or more isoforms. Alternative splicing is one of the major mechanisms providing proteomic complexity and functional diversification of the Bcl-2 family proteins. Pro- and anti-apoptotic Bcl-2 family members should function in harmony for the regulation of the apoptosis machinery, and their relative levels are critical for cell fate. Any mechanism breaking down this harmony by changing the relative levels of these antagonistic proteins could contribute to many diseases, including cancer and neurodegenerative disorders. Recent studies have shown that manipulation of the alternative splicing mechanisms could provide an opportunity to restore the proper balance of these regulator proteins. This review summarises current knowledge on the alternative splicing products of Bcl-2-related genes and modulation of splicing mechanisms as a potential therapeutic approach.Received 5 January 2004; received after revision 31 March 2004; accepted 6 April 2004     

绵羊卵母细胞不同采集方法对体外成熟培养的影响

为提高绵羊卵巢卵母细胞的采集效率,提供用于卵母细胞体外成熟培养和体外受精的更多优质的成熟卵母细胞,试验利用抽吸法和剖切法2种采集方法采集绵羊卵巢卵母细胞进行体外成熟培养并对其效果进行了对比研究.结果表明剖切法获得的卵子数量显著高于抽吸法(P<0.05),而所用时间则无显著差异(P>0.05);A、B级卵母细胞的比例在剖切法中显著高于抽吸法(P<0.05),抽吸法所采集的C级细胞显著高于剖切法(P<0.05);剖切法中卵丘扩散率和第一极体排出率要显著高于抽吸法(P<0.05).     

拓展高校学报双向展示功能探析

随着高等教育和期刊业的改革和发展,高校学报面临着前所未有的机遇和挑战,学报是反映本校教学科研成果的窗口功能定位受到了较大的冲击。学报界有种共识：办学报的目的应该是“提高”而不仅仅是“反映”。因此,应使学报在更好地为本校教学科研服务的同时,也要为整个社会服务,努力拓展学报的双向展示功能：争取校内优稿,提高展示功能的深度;大胆开放办刊,提高展示功能的力度。     

目前的离奇 心中的芜杂--《朝花夕拾》中鬼魅世界之探究

《朝花夕拾》不仅记载了鲁迅先生的绍兴生活及南京读书,日本留学,回国工作的经历,而且更深刻地反映了他对当时社会现实的认识,表现了他自我内心世界的情态,展示了对故乡风情民俗的留恋,文集中所突出描绘的独特的鬼魅世界,以及亲友亡故之往事,既是现实社会的观照,也是鲁迅先生暮年心态的折射,不家乡土风习的撷趣。