Cardiac protective role of a novel erythrocyte-derived depressing factor on rats and its Ca^2＋ mechanism

The cardiac protective role of a novel erythro-cyte-derived depressing factor (EDDF) on spontaneous hy-pertensive rats (SHR), calcium overload (CaO) rats and Wistar rats and its mechanism was evaluated. Mean artery pressure (MAP), heart rate (HR) and LVdp/dtmax were measured by physiological recorder. The effect of EDDF on the Ca2+-ATPase activity in myocardial sarcoplasmic reticu-lum (SR) of CaO rats was determined by inorganic phos-phate assay. Calcium transport in myocytes was measured by 45Ca2+ radioactive isotope measurement. The phosphoryla-tion levels of extracellular signal-regulated protein kinases (ERK1/2) in myocardial tissue of SHR and CaO rats were measured by Western blot method. And the ultrastructures of cardiac muscle cells were observed with the transmission electron microscope. The results indicated that EDDF could significantly decrease MAP, HR and LVdp/dtmax in a dose dependent manner (P < 0.05). It seems that the mechanism might relate with activating the Ca2+-APTase, enhancing the uptake and release of Ca2+ from SR (P < 0.05), decreasing the phosphorylation levels of ERK1/2 of myocytes (P < 0.01) and lightening the ultrastructural lesion of cardiac muscle cells. In CaO rats, the Ca2+-ATPase activity decreased clearly com-pared to control (64.99 7.16 vs 94.48 7.68 nmol·min-1 ·mg-1 protein, P < 0.01), while EDDF (100 mg/mL) could significantly increase the activity (87.93 ?9.54 vs 64.99 ?7.16, P < 0.05, n = 7). Both uptake and release rate of Ca2+ (祄ol 45Ca2+/g protein/min) from myocardial SR of CaO rats re-markably decreased compared to control (32.40 ?2.70 and 15.46 ?1.49 vs 61.09 ?10.89 and 25.47 ?4.29, P < 0.05); EDDF (100 mg/mL) could significantly stimulate their activi-ties (50.48 6.76 and 21.76 2.75 vs 32.40 2.70 and 15.46 1.49, P < 0.05). EDDF could evidently down-regulate the phosphorylation of ERK1/2 in myocardial tissue from SHR and CaO rats (P < 0.01), lighten the ultrastructural lesion of cardiac muscle cells of SHR as well. It is concluded that EDDF seems to play protective roles on both structure and function of heart, which closely related with amelioration of Ca2+ transport and inhibition of Ca2+-MAP kinase pathway.     

驾驶困倦预警系统中眼部状态识别的研究

为判断驾驶员是否处于疲劳驾驶状态,通过对人脸正面图像中的眼部状态的研究,提出了一种判断算法.首先基于灰度投影曲线和人脸几何特点提取驾驶员的眼部区域,然后利用事先提取的驾驶员睁眼时的瞳孔区域模板在该区域进行匹配,通过匹配初步判断出驾驶员是否属于疲劳驾驶.实验结果表明,该算法简单高效,在满足一定外部条件下,误判率较低.     

基于灰度共生矩阵的模糊神经网络FuCMAC在图像分割中的应用

文中提出了一种改进的CMAC神经网络(FuCMAC),与经典的FCMAC相比,其逼近精度得到提高,解决了CMAC系列神经网络逼近精度不高的弱点.在颅脑磁共振图像分割仿真实验中,把当前像素点的子图像的纹理特征和该像素点的灰度值作为该像素的特征向量,将该特征向量作为神经网络的输入,结果表明其具有较高的分割准确性.     

SAR图像的特征提取与目标识别

针对已有的SAR图像自动目标识别方法效果不太好的问题，提出了SAR图像的自动目标识别三种方法，即采用灰度特征的目标识别，采用栅格特征的目标识别，和采用模版特征的目标识别.理论和实验表明，采用模版特征的目标识别效果比较好.     

纸币清分图像识别算法研究

针对国产纸币清分机在图像识别技术上,存在挑残能力弱和分类一致性差的缺点,提出了3种基于图像识别技术的算法。通过对采集的图像数据,采用五线找点算法对纸币大小进行判定纸币的面额;根据加权灰度值提取纸币图像的特征区域判正反;采用网格划分法统计背景点与纸币图像点的数量关系判定纸币的残缺率。     

行业

牌照尚赫、美乐家获批直销牌照，保健品缓抗疲劳有水分，仙妮营德陈得福现身重庆开分店，玫琳凯签约CDP集团无缝对接HR管理，宝健青岛嘉年华捐建希望小学。[编者按]     

基于中值滤波去噪和小波融合的乳腺图像增强方法

将小波变换的多分辨率分析理论应用于图像融合中,提出了一种既能改善图像整体对比度,同时也能增强乳腺图像的组织细节结构的方法.实验结果说明了该方法的有效性.     

基于e-HR理论人力资源系统的开发研究

文章通过国内人力资源管理软件功能的分析，总结普遍存在的问题，结合目前最新的人力资源管理行业模型e-HR的理论，对某大型国有企业的人力资源系统进行设计和开发，旨在为此集团的人力资源管理找寻起一个标准化，规范化，网络化的工作平台，提供全方位的人力资源管理、分析、决策支持服务，实现全面的人力资源管理。     

谈兰州石化海外技术服务项目的HR管理

概述了兰州石化公司海外技术服务项目HR管理的发展情况和取得的成效。通过介绍兰州石化海外技术服务项目的HR管理发展背景、HR管理方法模式和HR管理取得的成效，对在国际形势不断变化、竞争不断加剧环境中的企业，就如何更好的开展海外技术服务业务提供一些有益经验，以供石化企业发展海外对1：3支持派员项目参考，相互交流借鉴。     

基于图像识别技术的煤岩识别研究与实现

应用图像处理技术判断煤岩介面及煤层厚度．根据煤岩灰度值和纹理的不同，对煤岩的灰度值和纹理分别进行提取，以此为判断依据进行煤岩识别．