Glucocorticoids in T cell apoptosis and function

Glucocorticoids (GCs) are a class of steroid hormones which regulate a variety of essential biological functions. The profound anti-inflammatory and immunosuppressive activity of synthetic GCs, combined with their power to induce lymphocyte apoptosis place them among the most commonly prescribed drugs worldwide. Endogenous GCs also exert a wide range of immunomodulatory activities, including the control of T cell homeostasis. Most, if not all of these effects are mediated through the glucocorticoid receptor, a member of the nuclear receptor superfamily. However, the signaling pathways and their cell type specificity remain poorly defined. In this review, we summarize our present knowledge on GC action, the mechanisms employed to induce apoptosis and the currently discussed models of how they may participate in thymocyte development. Although our knowledge in this field has substantially increased during recent years, we are still far from a comprehensive picture of the role that GCs play in T lymphocytes. Received 20 August 2005; received after revision 27 September 2005; accepted 10 October 2005     

代数体函数的正规定理

证明了代数体函数的正规定理:设W为区域D内的一个k-值代数体函数族,若对p D,其充分小的邻域U(p)使得对f W至多有k个分支点(重点按重数记),又W中每个函数都不取固定的3个互不相同的复数,则W在D内正规.     

夫妻日常家事代理权初探

本文阐述了家事代理权的含义、特征和性质．提出了我国建立日常家事代理权制度的必要性，重点论述了日常家事代理权的适用范围及其法律后果。     

非线性互补问题的可行性

给出了关于非线性互补问题的a-例外簇的定义，并据此给出了可行性定理。     

Lω-空间中的ωδ-Lindelff性质

在Lω-空间中引入ωδ-Lindelǒff性质和弱ωδ-Lindelǒff性质的概念，证明了ωδ-Lindelǒff性质和弱ωδ-Lindelǒff性质是ωδ-闭遗传的，并且在（ω1,ω2）δ-同胚映射下，它们是弱拓扑不变性质。     

算子cosine函数族与二阶发展方程的初值问题

讨论了定度域在ＲＨｎ（）上的广义微分算子生成的正则算子ｃｏｓｉｎｅ函数，并将其结果应用于讨论发展方程，给出了一类二阶发展偏微分方程Ｃａｕｃｈｙ问题的解     

关于 n-次积分 C-半群和存在族的注记

讨论了关于ｎ—次积分Ｃ—半群的一些性质，并给出了指数有界ｍｉｌｄｎ—次积分Ｃ—存在族的Ｈｉｌｅ－Ｙｏｓｉｄａ型定理，推广了文［８］定理４．１的结果。     

浅析我国成长期家族企业人力资源管理策略

针对成长期家族企业人力资源管理的现状,分析了其所面临的主要问题与这些问题背后的深层原因,并提出了成长期家族企业人力资源管理的解决对策。     

均匀分布族U（θ,cθ）中的经验Bayes检验

考虑均匀分布族U(θ,cθ),f(x|θ)=((c—1)θ)~(-1)I_((θ.cθ))(x),x,θ∈(0,∞),c>1中检验问题H_0:θ≤θ_0(?)H_1:θ>θ_0的经验Bayes检验。本文证得了经验Bayes检验的收敛速度。     

Systemic therapy: An overview

An outline is given of the historical development of systems ideas within the field of therapy. A history of systemic therapy is provided, from the early days of the Mental Research Institute to recent influences upon therapeutic practice. Key applications of theory are described and current areas of debate are highlighted.