A new method for uniform local heating deep in body using ultrasound phased-array system

A new method for targeted heating of deep tissue was developed by using an ultrasound phased-array system which can generate various multiple foci patterns by electronically changing its amplitude or phase pattern. This method involves using a technique of combining switching and rotating of multiple foci patterns to create a uniform temperature over tissue volumes in various size. Using this method, the target tissue deep in the body can be heated to a specified temperature, which gives conditions for thermo-sensitive liposomes release. A simulation study for a 108-element, spherically sectioned array was performed to determine an optimal heating scheme from a set of multiple focus fields which were produced by inputting different combinations of phases and amplitudes. Comparisons of a static multiple foci field, the switched fields and the switched-rotated fields indicated that the technique of combining switching and rotating of multiple foci patterns has advantages of both lowering the peak temperature and evening the temperature distribution. The simulation results also show that the therapeutic heating zones in various size employing the combined method. These results offer significant data for designing thermotherapy equipment for tumor-specific drug release with thermo-sensitive liposomes.     

试论传统气论的系统论意义简

以中医和道教理论为主干组成的中国传统气论是现代人体系统论的“近亲”。它把人看做是一个不可分割的“活结构”,在整体观、联系观、恒动观等多方面与现代系统论对生命规律的认识论有高度的一致性。在这个意义上,传统气论是崭新的,它可以为现代科学、哲学提供一些新的思路。同时它又是古老的,由于本身的历史局限,使它没有走上以准确、精确为基本要求的科学殿堂。     

含作业到达时间的同类机调度问题启发式算法

研究了目标函数是最小化完成时间和的同类机调度问题,其中作业到达时间可能不同.此问题被证明是强NP-hard问题.由于同类机调度是一种重要的平行机调度问题,而最小完成时间和目标是最常见的正则目标之一,因此完成时间和的同类机调度问题在相关研究领域具有非常重要的地位.为此问题建立数学模型,通过对单机和同型机的相应问题研究成果的推广,提出6个启发式算法,给出算例及其计算结果,并通过实验对算法的性能及算法适应的情形进行了分析.     

Comparison study of chitosan/β-cyclodextrin and carboxymethyl chitosan/β-cyclodextrin microspheres

To compare two microspheres of chitosan/β-cyclodextrin and carboxymethyl chitosan/β-cyclodextrin loaded theophylline as pulmonary sustained drug delivery carriers, the characteristics and ciliotoxicity were studied. The drug loadings of chitosan/β-cyclodextrin and carboxymethyl chitosan/β-cyclodextrin microspheres were 21.09% and 21.42%, and the encapsulation efficiencies were 91.40% and 92.80%. The distributions of 50% (d _0.5) of chitosan/β-cyclodextrin and carboxymethyl chitosan/β-cyclodextrin microspheres were 4.89 and 5.83 μm, respectively. Both microspheres showed spherical shape with smooth or wrinkled surfaces. FT-IR of chitosan/β-cyclodextrin microspheres demonstrated that theophylline had formed hydrogen bonds with chitosan and β-cyclodextrin, while for the carboxymethyl chitosan/β-cyclodextrin microspheres theophylline had interaction with carboxymethyl chitosan. The moisture absorption showed that an equilibrium was reached within 24 h. The two microspheres possessed better adaptability. In vitro release of theophylline from chitosan/β-cyclodextrin microspheres was slower than that from carboxymethyl chitosan/β-cyclodextrin microspheres at pH 6.8. Biography: LI Ruobao(1968–), male, Associate professor, research direction: foundation research of respiratory system.     

肝素化抗凝血材料的键合方式与肝素释放速率间的关系

通过对3种不同键合类型的肝素化材料及其肝素释放速率的研究指出Tanzawa临界释放速率理论的局限性。对于肝素化材料,一定量肝素的释放并非其具备抗凝血性能的必备条件,只要肝素的立体构型不发生变化且可自由运动,即具备潜在的抗凝性能。     

一类半对称度量循环联络

讨论了半对称度量循环联络的截面曲率，定义一类半对称度量循环联络，证明了Ｓｃｈｕｒ定理成立，并导出某些性质。     

在有机化学实验教学中实施环保教育的尝试

在有机化学实验教学过程中通过合理安排实验内容、改进实验仪器和实验装置等方法与途径渗透并实施环保教育 ,增强学生的环保意识和环保责任感 ,取得了满意的效果     

用于化学实验温度测量的精密测温仪制作

本文主要详细阐述了精密测温仪的制作和使用。     

恒稳磁场效应对多元束配合物体系显色反应影响的研究(Ⅱ)

研究了恒稳磁场效应对W（V）－KSCN－RhB－PVA124体系显色反应的影响,发现在一定范围内,恒稳磁场能显著地提高该多元配合物体系显色反应的灵敏度．在0．05μg／mLW（V）0．7％KSCN,0．05％TiCl31．50mol／LHCl．0．12％PVA1240．0045％的RhB和室温条件下,强度为80mT的恒稳磁场能将最大吸收波长580nm处的显色灵敏度提高65．1％．     

气象杂波环境下二维次序统计量恒虚警检测器

利用实际的气象杂波数据 ,研究了其CFAR处理问题。基于FFT处理技术 ,比较了CAGO -CFAR检测器、CLUTTERMAPPING -CFAR检测器和MX -OS -CFAR检测器的抑制气象杂波性能。针对存在的问题 ,提出了将通常在一维距离向进行的CFAR处理改为在R-Fd(距离 -多普勒频率 )二维平面进行 ,并利用次序统计量估计杂波幅度 ,形成新的稳健的 2D -OS -CFAR检测器。对实际杂波数据和仿真目标数据的处理结果表明所提出的 2D -OS -CFAR检测器具有良好的性能