凝血酶治疗新生儿上消化道出血疗效观察

选择５７ 例新生儿上消化道出血的患者,随机分成２ 组,采用凝血酶制剂进行对照治疗观察．结果表明：治疗组３１ 例,显效率为９３ ．５ ％ ,平均止血时间（１ ．３４ ±０ ．６３） ｄ;对照组２６例,显效率为５３ ．８ ％ ,平均止血时间（３ ．２２ ±０ ．５２） ｄ,２ 组比较,治疗组的疗效明显优于对照组（ Ｐ＜ ０ ．００１） ．     

奥扎格林钠治疗早期脑梗死的疗效观察

目的：观察丹奥对早期脑梗死患者的治疗效果。方法：在临床选取早期脑梗死患者,随机分为两组各80例。治疗组在常规治疗的基础上,给丹奥对照组只用常规治疗。采用全国第四届脑血管病学术会议通过的“脑卒中患者临床神经功能缺损程度评分标准”进行疗效评定。结果：丹奥治疗早期脑梗死,两周后评定临床神经功能缺损程度。结果优于对照组。结论：丹奥治疗早期脑梗死,疗效明显,未发现不良反应,可作为治疗早期脑梗死的主要药物之一。     

脑瘫患儿家长心理问题及对策

目的:探讨脑瘫患儿家长的心理状态,为临床工作提供参考。方法:采用症状自评量表(SCL-90),调查患儿家长存在的心理问题。结果:根据患儿家长存在的不同心理问题采取相应的措施,减轻患儿父母心理负担,提高治疗依从性。结论:脑瘫患儿家长存在心理障碍,在临床工作中要注意加强对患儿家长进行心理护理。     

缺血性脑卒中蒙西医治疗现状

缺血性脑卒中是最常见的脑血管病,严重威胁着人类健康。不同的医学体系对其治疗亦不同,现就蒙医与西医对缺血性脑卒中治疗的现状作一综述。     

Detection of Grass Carp Hemorrhage Virus （GCHV） from Vietnam and Comparison with GCHV Strain from China

Grass carp plays an important role in small-scale aquaculture in Vietnam. However, a severe disease, known in Vietnam as “Red Spot Disease“, is causing significant economic loss in grass carp aquaculture. In this study, the tissue samples isolated from the grass carp with Red Spot Disease in Vietnam are investigated and eomparied with the control GCHV isolated in China by experimental infection, culture cell infection, serological cross reactivity, and RT-PCR amplifica-tion. Infected grass carp exhibits hemorrhage symptoms about 5 days after experimental injection with GCHV-V (Vietnam) strain. The symptoms and lethality induced by the GCHV-V strain are identical to that induced by the Chinese GCHV-9014 strain. The Chinese GCHV-873 strain in-duces typical cytopathogenic effects in 4 cell lines, such as CIK, CAB, FHM and GCO, from the6 fish cell lines examined. No cytopathogenic effects are observed in all the 6 examined cell lines,including CAB, FHM, CIK, EPC, CCO and G(X), infected by the GCHV-V strain and GCHV-9014 strain. Immunodiffusion assays demonstrate an obvious cross-reactivity among three GCHVstrains. Precipitin lines are clearly observed not only between the anti-GCHV-873 serum and thetwo strains GCHV-873 and GCHV-9014, but also between the anti-GCHV-873 serum and the GCHV-V strain. GCHV can be detected by immunodiffusion assays after three generations of blind propagations in the cell lines inoculated by GCHV-V strain. This implicates that GCHV-Vviruses have been replicated and amplified despite there being no cytopathogenic eifects observed in these examined cell lines. Three genome segments of GCHV, including S8, S9 and S10, are amplified by three sets of PCR primers designed according to the segment sequences published re-cently. The Q8fp and Q8rp primer set specific for genome segment S8 amplifies a 955 bp frag-ment from the extracted sample of diseased fish with Red Spot Disease, and the fragment size is i-dentical to that amplified by the same primer set from control GCHV-873 strain. Simultaneously,the Q9fp and Q9rp primer set specific for genome segment S9 generates a same 635 bp product,and the Q10fp and Q10rp primer set specific for genome segment S10 produces a same 697 bp fragment from both template samples of diseased fish with Red Spot Disease and control GCHV-873 strain. The RT-PCR amplification and corresponding size comparison data indicate that the three GCHV-V genome segments extracted from the diseased grass carp with Red Spot Disease in Vietnam should be identical to that in control GCHV-873 strain from China. The data confirm that the causative agent of grass carp Red Spot Disease in Vietnam is a virus, and the virus is closely similar to GCHV strain in China.     

高血压脑出血术后应用地塞米松的临床评价

目的 探讨高血压脑出血术后应用地塞米松减轻脑水肿的临床效果。方法 对50例病人应用地塞米松减轻脑水肿。结果 合并应激性溃疡17例，心功能不全32例，骨功能不全16例，高血糖症28例。结论 脑出血术后应用地塞米松治疗脑水肿，诱发并加重了脑出血的并发症，增加了脑出血的死亡率。     

貌似炎性脑病的脑肿瘤临床分析

报告的 7例患者均在病前有“感冒”病史 ,临床症状、体征及脑脊液检查均符合脑炎或脑膜炎 .最后经病理学和头部CT以及脑脊液细胞学检查证实为脑肿瘤 .提示感冒只能看作是一切疾病可能病因 ,不能作为炎性脑病的主要病因     

少量高血压脑出血微创手术与保守治疗疗效对比研究

目的比较微创血肿清除术与保守治疗少量血肿(30 m L)的高血压脑出血患者临床疗效.方法将临床确诊为颅内深部少量出血的96例高血压患者作为研究对象.将所有研究对象随机分为两组:微创手术治疗组(微创组)(50例患者)和保守治疗组(对照组)(46例患者).微创组采用微创穿刺血肿清除术对高血压脑出血患者颅内血肿进行微创穿刺清除,对照组给以常规药物保守治疗.通过检测神经功能缺损评分、Glasgow昏迷评分、死亡率、再出血率、平均住院时间和格拉斯哥预后(GOS)评分情况,对两组患者的临床疗效和短期预后进行对比分析.结果 1)神经功能缺损评分结果显示:微创组患者神经功能恢复程度显著优于对照组,两组数据比较差异显著,具有统计学意义(P0.05).2)患者入院1周后Glasgow昏迷评分(GCS)检测结果显示:微创组明显好于对照组,两组数据比较差异显著,具有统计学意义(P0.05).3)微创组再出血的发生率较对照组相比有增高的趋势(P0.05),死亡率两组数据比较无显著统计学意义(P0.05).4)微创组患者平均住院时间要短于对照组(P0.05).5)采用格拉斯哥预后(GOS)评分系统对出院半年后患者的生存质量进行评估,结果显示微创组GOS得分情况明显高于对照组,两组数据比较差异显著,具有统计学意义(P0.05).结论 1)微创手术治疗能明显改善少量血肿的高血压脑出血患者意识状态和神经功能障碍,促进功能恢复,缩短患者平均住院时间,患者的短期预后和恢复效果明显.2)微创血肿清除术能显著缩短少量血肿的高血压脑出血患者住院时间,减少患者住院费用,有助于缓解患者经济负担.     

高血压性脑出血脑活素的临床应用

文章结合临床实践分析,提出在合理降颅压及控制血压于适宜水平的基础上早期应用脑活素对改善脑细胞功能、催醒及促进出血灶的吸收均有明显辅助治疗效果。     

产后出血的护理体会

总结产后大出血的预防、监测、护理对策.并对在我院住院的23例产后出血达800ml以上产妇临床资料进行了分析.结果显示:子宫收缩乏力是引起产后出血的首要原因,有产后出血危险因素存在的孕产妇易出现产后出血,出血量超过1700ml以上严重危及生命.提示:产科出血仍然是威胁孕产妇生命安全的首要原因.做好产后出血的预防、监测、急救、护理工作,才能降低其发病率、病死率,进而降低孕产妇死亡率.