具有液晶性的杯[4]芳烃衍生物的合成及性质研究

物理学家早就预言 ,如果能获得碗状分子 ,而这个“碗”中又放一个原子或原子团的话 ,必将能获得具有特殊光学特性的液晶材料[1] .而杯芳烃就可以构成这样的“碗” .杯芳烃因其特殊的疏水功能和选择性配合金属离子的特性 ,以及易于通过母体杯芳烃合成具有各种特性的杯芳烃衍生物而得到广泛应用[2～ 7] ,被称为第三代超分子 .根据杯芳烃及其衍生物具有对金属离子的选择性配合作用及发光的敏化作用 ,我们设计并合成了既有液晶性 ,又能配合金属离子和敏化金属离子发光的杯 [4 ]芳烃衍生物 (Ｅ) ,并对其性质进行了研究 ,取得了一些未见报1　实验1…     

虚拟项目教学法在模拟电子技术教学中的应用

虚拟项目教学法是基于计算机模拟仿真技术的一种教学活动。将虚拟项目教学法应用到模拟电子技术的教学中,通过项目任务的设计、项目准备、仿真实施及总体评价展开教学。该方法不仅可以达到传统项目教学法的教学目标,而且可以扩大学生的参与面,降低教学成本。实践表明,该方法适合于应用型人才培养目标下的模拟电子技术教学。     

Multisim 9在电子线路课程设计的应用

结合电子线路课程教学、电子线路课程设计实践,通过二级放大电路实例介绍Multisim 9软件在电子线路课程设计中的应用,该软件能优化电路设计,实现电路功能仿真及提高电路设计开发水平与分析电路的能力。     

Hélène Metzger: the history of science between the study of mentalities and total history

In this article, I examine the historiographical ideas of the historian of chemistry Hélène Metzger (1886–1944) against the background of the ideas of the members of the groups and institutions in which she worked, including Alexandre Koyré, Gaston Bachelard, Abel Rey, Henri Berr and Lucien Febrve. This article is on two interdependent levels: that of particular institutions and groups in which she worked (the Centre de Synthèse, the International Committee for History of Science, the Institut d'Histoire des Sciences et Techniques (Sorbonne) and the École Pratique des Hautes Études) and that of historiographical ideas. I individuate two particular theoretical aspirations pursued by the historians in Metzger's milieu: the ideal of total history and the study of the human mind. These two objectives were seen by Metzger and many others as implicating each other. Moreover, Metzger and other historians wanted to integrate the practice of commentary of texts in the realisations of those ideals. I argue, however, that these objectives proved very difficult to realise at the same time. One tradition which stemmed out of these discussions, exemplified by Bachelard, Canguilhem and Foucault, focused on the mind and knowledge, and renounced commentary of texts and total history as it was understood by the historians of the Centre de Synthèse. The latter, however, did not really pursue the study of the mind. Moreover, historians like Metzger and Koyré who practised an attentive analysis of texts could not realise total history.     

Inhibition of DNA restrictive endonucleases and Taq DNA polymerase by trimalonic acid C60

Activities of trimalonic acid fullerene (TMA C_60) on DNA restrictive enzymatic reaction were investigated by using two restrictive endonucleases Hind III and EcoR I and plasmid pEGFP-N1 with single restric-tive site for both enzymes. Meanwhile, TMA C60 was also tested to clarify its effects on polymerase chain reaction (PCR) with the catalyst of Taq DNA polymerase and the template of plasmid pEGFP-N1. The products from restrictive reactions or PCR were detected by agarose gel electrophoresis. It was found that the product amounts from restrictive reactions or PCR decreased significantly with addition of TMA C60. The inhibition by TMA C60 was dose-dependent and IC50 values for reactions of Hind III, EcoR I and PCR were 16.3, 6.0 and 6.0 μmol/L, respectively. Addition of two scavengers of reactive oxygen species (ROS), L-ascorbic acid-2-phosphate ester magnesium and sodium azide at the con-centrations of 2―10 mmol/L did not antagonize the activities of TMA C60 against PCR and two restrictive reactions. However, increase of Taq DNA polymerase amounts in PCR system antagonized the activities of TMA C60. These data implied that TMA C60 was able to inhibit the activities of the three above-mentioned enzymes involved in DNA metabolism, and that this inhibition probably did not correlate to ROS.     

智能小车辅助平台的设计与实现

讨论了一种以教学为目的的智能小车开发平台的设计思想,描述了智能小车的机械平台结构,给出了以FreescaleMC9S08GB60为主控芯片的、开放的硬件平台设计,提供了可供用户自行“定制开发设计”的、简单易学的PC方软件平台设计。该辅助开发平台主要针对中小学课外科技活动开发,也可供高校学生进行智能小车设计、参加智能小车设计竞赛之用。     

四种操作系统共存于同一台计算机中的实现

针对很多计算机应用场合 ,要求一台计算机具有多种职能 ,需要多种操作系统支持的需求 ,本文讨论了多种操作系统共存于一台计算机中的技术     

Analysis of intron sequence variability of the conservative HMG-box of Sox9 genes in allotetraploids and their original parents

The Sox genes of allotetraploids and their original maternal red crucian carp (Carassius caassius red var.) and original paternal common carp (Cyprinus carpio L.) were detected by PCR with the designed primers based on the conserved HMG-box sequence in different species. Sequencing of Sox genes indicated that two Sox9 genes (Atsox9a and Atsox9b) existed in allotetraploids, while only one Sox9 gene existed in red crucian carp (Rcsox9a) and common carp (Ccsox9b) . All of the four Sox9 genes contained an intron in the HMG-box. with the sizes of 413 bp, 703 bp, 401 bp and 714 bp, respectively. Moreover, the introns obeyed the rule of "GT-AG" . A high similarity was observed between introns of Atsox9a and Rcsox9a (94.4%), Atsox9b and Ccsox9b (97.8%). Interestingly, the deduced amino acid sequences of their corresponding exons all shared 100% identity. Thus, introns of the HMG-domain of Sox9s in allotetraploids and their original parents have not only the length polymorphism but also intron variability. Our results provide significant molecular evidence for the origin and evolution of allotetraploids.     

基于LPC2214的Flash存储器的应用

介绍了Flash存储器K9F5608U0C和SST39VF160的特性,给出了微处理器LPC2214与它们的硬件连接电路图,以及对它们进行读、写、擦除等操作的应用软件.     

李益首次从军时间地点考辨

本文纠正了长期以来人们对李益首次从军时间和地点的错误认识,认为其首次从军时间应在大历九年至大历十二年间,而非建中初;地点在凤翔节度使李抱玉军中,而非邠宁节度使韩游瑰、凤翔节度使邢君牙或渭北节度使臧希让军中.