Therapeutic applications of bone marrow-derived stem cells in liver transplantation for end-stage liver diseases

Today, liver transplantation (LT) is the only established treatment for end-stage liver diseases. The de- velopment of LT, including OLT, cadaveric LT, split LT, living donor LT (LDLT), brings hopes to patients with these diseases. However, increasing donor shortage, rejection and life-long immunosuppression with its side effects are the major limitations of this therapy strategy. Bone marrow-derived stem cells (BMDSCs) are capable of differentiating into hepatocyte-like cells and contribute to liver injury repair. The microenvironment of liver injury caused by rejection, ischemia/reperfusion, loss of liver mass, recurrence of HCV and "small-for-size syndrome" after LT can attract a variety of bone marrow-derived stem cell population to the peripheral circulation and then migration to the injury liver to promote the hepatic function restoration. Additionally, BMDSCs can also take part in the functional regeneration of living donor liver after LDLT. This participation in liver regeneration may be associated to the interac- tion between SDF-1and its receptor CXCR4, involving HGF, IL-8, MMP9, and VEGF/VEGFR-2. BMDSC with its bio-characteristics could maintain the allograft tolerance from different angles and in different ways. In conclusion, BMDSCs transplantation, as a new assistant therapeutic method for LT, will ex- pand the space of LT, and provide more survival opportunities for the patients suffering liver diseases in the future.     

软件补偿方法在测温智能仪表中的应用

软件补偿方法具有效果好、精确度高、成本低的优点。介绍了在研制多点巡回检测仪中采用的几种软件补偿方法：前向通道特性补偿使放大器等元件不因外界条件的变化而受到任何影响；引线电阻的补偿可实现引线电阻对系统无任何影响；热电阻、热电偶的非线性度补偿效果明显，节省开销。     

非线性非完整保守系统的稳定准则

本文采用不同于文献[8]的方法,研究了非线性非完整保守系统的稳定性问题,并给出了相应的稳定准则     

一类泛圈图

本文证明了如果G是2连通无爪图,G不是圈,n=|v(G)|>q,G的每个导出子图A都满足φ(a_1,a_2),且G中不存在W′作为其导出子图,则G是泛圈图。     

中国邮路问题的0-1规划解法

在用“奇偶点图上作业法”求解“中国邮路问题”时,需检查图中的每一个回路.当图中回路较多时,检查不便且易出错.针对此,本文建立了求解“中国邮路问题”的0-1规划模型,并给出了算例。     

岩芯筒压入地层的塑性力学问题

摘要首先从库仑定律出发导出了地层介质塑性流动条件。其结果类似于一般塑性力学中的Tresca,Mises条件。其次列出了轴对称地层塑性流动的微分方程组,并推出了其简化近似方程。最后提出了简化方程的特征线解法,并举例说明。     

模型优适度辨识含水层补给进口的原理、方法和应用

本文阐述了一种新的研究成果——用模型优适度寻找含水层主进水口位置的原理、方法和应用。模型优适度作为衡量地下水模型场势与原型(矿区)场势相似拟合程度的量度,它凭借含水层地下水场势对源点的响应差异,判别模型源点位置与原型源点位置是否一致、接近或偏离。本文给出了模型优适度的计算公式和用统计分析方法对动态矩阵施行标准化的公式推演过程。通过多次模拟试验,绘出优适度的等值线图,为华北某矿圈定含水层补给范围,进行注浆堵水,大大地降低了矿井涌水量,在实践应用中获得初步成功。     

浮雕造型机器人运动规划

本文论述了一种结构简单，行之有效的机器人运动规划系统，能迅速判断机器人与工件的关系，实现浮雕造型机器人无碰撞轨迹规划．