Cu（Ⅱ） effect on the conformation of regenerated silk fibroin in dilute aqueous solution

Much attention has been paid to the natural mechanism of silkworm spinning due to the impressive mechanical properties of the natural fibers. In this work, we studied the effect of Cu（Ⅱ） ions on the secondary structure of Bombyx mori regenerated silk fibroin （SF） in dilute solution by circular dichroism （CD）. The results indicate that a given amount of Cu（Ⅱ） induces the SF conformational transition from random coil to β-sheet, however, further addition of Cu（Ⅱ） is unfavorable for this conversion. Meanwhile, the conformational changes induced by Cu（Ⅱ） follow a nucleation-dependent aggregation mechanism, which is similar to that found in Prion protein （PrP） denaturation and Aβ-peptide aggregations, leading to the neurodegenerative disease. This work would help one understand further the natural spinning process of silkworm. Additionally, it would be significant for the study of the nervous system diseases, because silk fibroin, extracted in large amounts from Bombyx mori silkworm gland, could be a proper model to study PrP denaturation and Aβ-peptide aggregations.     

高精度步进压印机热误差的建模分析

为了消除由紫外光曝光所引起的步进压印机的热误差，以提高压印机的套刻对准精度，运用逐步回归分析法选取了压印机上温度测量点的数量，将压印机上布置的温度传感器从15个减少到6个，并建立了压印机温度测量关键点处的温度与压头在x、z方向热误差关系的数学模型．实验结果与模型计算结果的对比分析表明，模型的热误差预测精度在x方向可以达到899／6，而在z方向可以达到939／6．应用表明，该方法是一种在压印机热误差建模中选择温度测量关键点的有效方法，可避免热误差建模过程中的变量耦合问题，从而提高了模型的精确性．     

基于CTV100平台的DPTV系统的研究与实现

从硬件和软件两方面详细阐述了基于CTV100平台的DPTV系统,并给出了总体设计框图和设计流程图。本项目采用意法半导体公司(ST)的CTV100解决方案,实现了对传统模拟电视信号的高效数字域处理,显著提高了电视画面的图像质量;并通过采用基于32bitCPU的OS20嵌入式操作系统,实现了多种传统模拟电视无法实现的功能。     

纳米二氧化锆制备工艺的研究

实验用氨水作沉淀剂,与氯氧化锆在常温条件下进行液相沉淀反应,制备纳米二氧化锆.实验优化出制备纳米二氧化锆的最佳工艺条件:反应物氨水和氯氧化锆的摩尔比为2:1;分散剂浓度为2g/L;焙烧温度为750℃;氨水浓度0.2mol/L;氯氧化锆浓度0.1mol/L,在此条件下可获得较为分散均匀的纳米二氧化锆.     

仿射Weyl群(E～)6的a值5的左胞腔

Coxeter群的胞腔是1979年Kazhdan和Lusztig中定义的，这些胞腔理论在代数群的表示理论中发挥了重要的作用。对一些特殊的情况，胞腔的分类已经明确地给出了，例如，对于秩为2的群参见，对于An^-参见，对于a值4的典范型和或参见.本文利用时俭益的运算算法给出了仿射Weyl群E6^-的a值等于5的所有左胞腔。     

双机串口互联实现GPS数据的模拟读取

提出了一种利用两台以串口互相连接的计算机来实现对GPS全球定位系统定位信息的模拟发送和接收的方法。     

顺铂与DNA相互作用下的CD谱的测试

本文报导了ＤＮＡ与顺铂相互作用下的ＣＤ谱的测试过程及实验结果，并对作用机理做了初步分析．     

Changes in glycosaminoglycan sulfation and protein kinase C subcellular distribution during differentiation of the human colon tumor cell line Caco-2

Summary During the spontaneous differentiation (day 5 to day 15 of the culture) of Caco-2 cells, the sulfation of cell layer glycosaminoglycans increased, whereas protein kinase C activity was concomitantly redistributed from the membrane to the cytosol. The protein kinase C activators, 4-phorbol 12-myristate, 13-acetate and 1,2-dioctanoyl-glycerol inhibited glycosaminoglycan sulfation. By contrast, 4-phorbol 12, 13 didecanoate was ineffective.These results suggest that membrane-bound PKC may exert a modulatory effect on glycosaminoglycan sulfation, and this effect is gradually attenuated as Caco-2 cell differentiation progresses.     

A new indolic antiauxin, α-(5,7-dichloroindole-3-)isobutyric acid: its chemical synthesis and biological activity

Summary A new potent antiauxin, -(5,7-dichloroindole-3-)isobutyric acid has been synthesized and shown to inhibit auxin-mediated elongation ofAvena coleoptiles and to stimulate root growth of rice seedlings. Its activity is stronger than -(p-chlorophenoxy)isobutyric acid and is comparable to that of 2,3,5-triiodobenzoic acid, which are typical antiauxins.     

The role of repair in radiobiology

Summary Apart from cancer and mutation induction, radiobiological effects on mammals are mostly attributable to cell death, defined as loss of proliferative capacity. Survival curves relate retention of that capacity to radiation dose, and often manifest a quasi-threshold (shoulder). The shoulder is attributable to an initial mechanism of repair (Q-repair) which is gradually depleted as dose increases. Another form of repair, which is not depleted (P-repair), increases the dose required to deliver an average of one lethal event per cell (dose D₀). Neither form of repair can unambiguously be linked with repair of defects in isolated DNA. An important initial lesion may well be disruption of the complex structural relationship between the DNA, nuclear membrane and associated proteins. One form of P-repair may be restoration of that structural relationship.