Role of the δ 8 double bond of agroclavine in lysergic acid amide biosynthesis byClaviceps purpurea

Summary Agroclavine, given to actively-growing sclerotial tissue of a strain ofClaviceps purpurea which can not normally elaborate ergot alkaloids, was transformed by this tissue into lysergic acid amide with overall efficiency of approximataly 40%. By contrast, festuclavine (8, 9-dihydro-agroclavine) was not transformed, indicating specificity in the mechanism of lysergyl biosynthesis.     

反式蒈醛酸酯经差向异构化制取半缩醛内酯的研究

反式菊酸酯经臭氧化得蒈醛酸酯,然后在甲醇钠的甲醇溶液中发生差向异构,获得顺式蒈醛酸及它的半缩醛内酯的混合物,收率从原来文献报导的27％提高到60％。     

12—硅钼酸降解产物SiMo11铵盐的合成

在对SiMo_(12)杂多酸降解过程的研究中,首次从H_4SiMo_(12)O_(40)直接降解合成出其降解产物(NH_4)_8[SiMo_(11)O_(39)]·14H_2O。经组成分析,确认其为SiMo_(11)铵盐。利用紫外光谱分析、红外光谱分析、x射线粉末衍射、电位滴定、tga—dta热分析、薄板层析等现代分析手段对合成产物的性质进行了研究。     

Cerebral ischemia revisited: New insights as revealed using in vitro brain slice preparations

Summary The elucidation of the pathophysiological mechanisms of cerebral ischemia/hypoxia dictates the use of experimental models which mimic this disabling brain condition. In vivo experimental models have been available for many decades and are responsible for the bulk of, though incomplete, knowledge we have about these mechanisms. Since study in isolation of each postulated mechanism is impossible in vivo, the need for an in vitro experimental model has intensified in recent years. Consequently, rat and guinea pig hippocampal slice preparations have emerged as the models of choice. This review attempts to highlight some of the results obtained using brain slices in the study of cerebral ischemia/hypoxia and compare them to those obtained in vivo. Both the biochemical and the physiological correlates of energy metabolism, ion homeostasis, neurotransmission and neuromodulation of this brain condition are reviewed. The agreements, and especially the disagreements, between the in vivo and in vitro findings are emphasized. Details are given of the possible roles of both lactic acid, Ca²⁺ and excitotoxins in the neuronal damage inflicted by cerebral ischemia/hypoxia. Recent attempts to protect brain slices against experimental cerebral ischemic/hypoxic damage are also reviewed here briefly.     

绿色含硼加脂剂的制备与性能

将蓖麻油进行硼酸酯化,用氢氧化钠和三乙醇胺中和制备了一种绿色硼酸酯阴离子型皮革加脂剂,讨论了反应物料配比、反应温度、催化剂用量和中和方式对加脂剂稳定性及加脂性能的影响。结果表明当蓖麻油与硼酸的质量比为(3.0~4.0):1、催化剂用量为反应物质量的2%、反应温度为80~85℃时,制得的加脂剂具有良好的润滑性、稳定性,加脂效果与传统的磷酸化蓖麻油相当。工艺环境友好,简使易行。     

用复制酶基因cDNA探针检测表达病毒外壳蛋白基因马铃薯中的PLRV

利用马铃薯卷叶病毒（ＰＬＲＶ）复制酶基因３′端长约６００ｂｐ的ｃＤＮＡ，用缺口平移方法进行３２Ｐ同位素标记，制备成ｃＤＮＡ探针，通过核酸斑点杂交，对提纯的马铃薯卷叶病毒（ＰＬＲＶ）、病毒ＲＮＡ、ＰＬＲＶ感染的马铃薯汁液，表达ＰＬＲＶＣＰ基因的马铃薯叶片及块茎芽进行了检测．结果表明，３２Ｐ标记的复制酶基因ｃＤＮＡ探针特异性强、灵敏度高．可测得提纯病毒的最低含量为４０８ｎｇ／ｍｌ，病毒ＲＮＡ最低量为２７．８ｐｇ／ｍｌ，未转ＣＰ基因接种ＰＬＲＶ的马铃薯叶片提取液的最高稀释度为１３７５．接种ＰＬＲＶ的转ＣＰ基因的抗性马铃薯块茎芽和叶片提取液的最高稀释度为０～１／１５．此探针和只转入病毒外壳蛋白基因，不接种ＰＬＲＶ的转基因马铃薯汁液不发生反应．表明，探针只与ＰＬＲＶ基因组ＲＮＡ特异反应，而不与外壳蛋白基因及其ｍＲＮＡ反应，从而为表达ＣＰ基因的转基因马铃薯中ＰＬＲＶ的检测和抗病性鉴定建立了一种可靠的灵敏的分子生物学技术．此项技术已用于转ＣＰ基因马铃薯Ｄｅｓｉｒｅ，Ｆａｖｏｒｉｔａ，乌盟６０１和虎头的抗病性鉴定     

Graft of Polybutylene Terephthalate Meltblown Nonwovens by Plasma Initiation and Their Surface Performance

Main factors affecting the low temperature plasma initia-tion and graft modification of acrylic acid onto polybuty-lene terephthalate(PBT)meltblown nonwovens are stud-ied.The relations between hydrophilic performance ofthe product and plasma power,treating time,andmonomer concentration are investigated.The surfaceperformances of grafted products are analyzed.It is ob-tained that hydrophilic performance of PBT nonwovens isgreatly improved due to the etching of the plasma andthe introduction of polar groups so as to meet the needsof leukocyte depleting materials.     

杂多酸催化合成己二酸双酯的研究

采用磷钨酸催化合成了几种己二酸双脂，并讨论了己二酸二乙酸的合成条件，优化条件下，反应收率可达97％以上。     

Hepatic acid hydrolases of albino rats,Mastomys natalensis and albino mice duringPlasmodium berghei infection

Summary Changes in liver acid hydrolase activities during the infection of albino rats,Mastomys or mice withPlasmodium berghei are described. B-Glucosidase, B-galactosidase and N-acetyl-B-D-glucosaminidase exhibited widely different responses with acid phosphatase and cathepsin-B the least responsive and are likely to be causally related to immunity of animals.     

合成氢氰酸技术研究进展

介绍了合成氢氰酸的生产工艺,评述了国内外合成氢氰酸生产工艺的研究、生产现状以及发展趋势。