海芋凝集素的理化性质鉴定

采用葡聚糖凝胶１００（ＳｅｐｈａｄｅｘＧ－１００）从天南星科植物海芋（Ａｌｏｃａｓｉａｏｄｏｒａ（Ｒｏｘｂ）Ｃ．Ｋｏｃｈ）中分离出了一种凝集素（简称ＡＯＬ）．ＡＯＬ对兔血有较强的凝集效果,而对各类型人血的凝集活力较弱,在３种糖蛋白中,猪甲状腺球蛋白对ＡＯＬ的凝血活力抑制最强;ＡＯＬ对培养人外周血白细胞的转化率高达７９％,超过对照ＰＨＡ的转化率;用ＳｅｐｈａｄｅｘＧ－２００柱测得ＡＯＬ的相对分子质量为３１５００;用癌细胞体外培养的方法证明了ＡＯＬ对肺腺癌细胞株Ｐ１８具有较强的直接杀伤能力．此外还发现ＡＯＬ对温度（８０℃以下）、变性剂（盐酸胍和脲）有较高的稳定性,在ｐＨ６～１０的范围内相当稳定．     

1,6—二磷酸果糖制备研究：Ⅰ.菌种的筛选及培养条件

介绍了１,６－二磷酸果糖产生菌的筛选和最佳培养条件的确定,在所筛选的菌种中９５１８、９５１９号菌株均具较高的产１,６－二磷酸果糖酶系活力。其最佳培养条件为：培养温度２８℃,ｐＨ６．５。     

High-precision timing of the Quaternary standard samples with thermal ionization mass spectrometry (TIMS) U-series method

Two national stalagmite standard (GBW04412, GBW04413) and one international coral standard (RKM_4) have been determined by using thermal ionization mass spectrometry (TIMS) method. The values of ( 234 U/ 238 U) act , ( 230 Th/ 234 U) act and age are all consistent in error range with the standard values obtained by using α spectrometry.     

New evidence for the Qinghai-Xizang (Tibet) Plateau as a pilot region of climatic fluctuation in China

Over 40 a observed temperature data in 172 stations in China and historical proxy data were analyzed. Evidence suggested that during 1980–1994, the warmest year appeared first in southeastern part of the Qinghai-Xizang (Tibet) Plateau (henceforth SETP) and then gradually spread northwards and eastwards to eastern China. The climatic change on century time scale in recent 600 a shows 3 relatively warm and clod stages in China. Each warm and cold stage appeared first in Tibet Plateau (henceforth TP) and then in the Qilian Mountains, then in the eastern parts of China. The warm and cold stages in TP were 10–60 a earlier than in the eastern China. The facts show that TP is a pilot region of climatic fluctuation in China on the time scale shorter than 10³a.     

Preparation and optical properties of solid solution semiconductor (Zn x Cd1−x S) doped silica glasses

Semiconductor(Zn_xCd_1−x S) doped silica glasses were prepared by Sol-Gel process andin situ growth technique. The structure of the materials was characterized by X-ray diffraction technique, the particle size of semiconductor crystallites from X-ray patterns was estimated less than 10 nm. From absorption spectra, it is obtained that the absorption edges shifted to short wavelength direction when Zn contents increased, and the absorption edge can be adjusted from 2.46 eV to 2.96 eV by controlling Zn contents. The third-order nonlinear optical susceptibility was studied at 532 nm with 8 ns pulse laser by degenerate four wave mixing (DFWM) technique.     

Signal transduction pathways mediated by colony stimulating factor-1 receptor

Colony-stimulating factor-1 (CSF-1), which is necessary for cell proliferation and differentiation, regulates both immediate and delayed early responses throughout G1 phase. The binding of CSF-1 to its receptor (CSF-1R) triggers phosphorylation of the receptor and its intrinsic tyrosine kinase. The activated receptor binds directly to cytoplasmic effector proteins, which induce multiple-signal transduction pathways. CSF-1 can induce the c-myc gene expression via Ras and Ets-related proteins. The expression of c-fos/jun family genes is also targeted following the activation of Ras. CSF-1R activates STAT1 and STAT3 to participate in signaling, but JAKs do not appear to contribute to signaling by CSF-1R. CSF-1R activates PI3-kinase, and PI3-ki can interact with downstream proteins by the MAPKK-related pathway independent of Ras/Raf. PC-PLC can enforce signaling in response to CSF-1. Furthermore, the turnover and dephosphorylation by the phosphatase SHPTP1 of CSF-1R are the major mechanism in the negative regulation of signaling by CSF-1R     

Neuropeptide Y receptors in a protozoaStylonychia mytilus

Radio ligand binding assays(RLBA) were used to study neuropeptide Y (NPY) receptors in a protozoa Stylonychia mytilus. The experimental results showed that 2-3×10+3/mL Stylonychia cells incubated in Pringsheim solution which contained 3H-NPY could specifically bind 3H-NPY and concomitantly present saturable characteristic. This suggested that Stylonychia possessed some specific binding sites for NPY. Scatchard transformations of binding assay for the NPY receptors at 25℃ are compatible with the specific activity of 42.47 fmol/10+3 cells and the binding equilibrium constant of 0.113 nmol/L. The data of 125I-NPY binding assay to the membrane protein extract of Stylonychia indicated that there was a significant difference between the amount of total bound and nonspecific bound of 125I-NPY. This result indicated that NPY receptors were probably localized mainly on the cell membrane.     

十八烷基（2—亚硫酸）乙基二甲基铵的合成

由Ｎ,Ｎ－二甲基十八烷基胺和乙撑亚硫酸酯反应合成十八烷基（２－亚硫酸）乙基二甲基铵是一种新型的亚硫酸内酯型两性表面活性剂,经红外光谱和核磁共振谱分析,确定了该化合物的结构,该两性表面活性剂合成方法简单,原料易得,用途广泛,有发展前途。     

成组技术中面向对象的参数化模型

针对传统成组技术中的编码系统难以使用、编码不够精确和重用困难等问题,提出在成组技术中构造面向对象的参数化模型．该模型用类来描述零件簇,构成零件类的结构层次,生成零件描述的框架;用参数化方法从零件类实例化生成对象,以对象来表示具体的零件;查询时,以零件的特征和零件的具体参数来驱动,加速搜索的过程,并使结果更加精确;找到相同或相近零件对象后,在某个类层次上重用以前的设计．该模型的提出为成组技术的应用提供了新的途径．     

（H,G）—变换和拟正则半群

研究一般的（Ｈ,Ｇ）型变换通过适当合成变换后生成拟正则半群;并建立了Ｇ－变换和（Ｈ,Ｇ）型变换两者之间的拟共形共轭关系．对于给定的一个拟正则半群,构造了一个不变共形结构ＧΓ,使得该半群中的每个元素在这个不变共形结构下保持Ｇ－变换不变．