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RICHIA NET是日本弘康集团属下的一个电子商务平台。其产品的研发基地在日本；生产基地在中国；亚太地区发货中心在香港；网站维护在集团总部所在地东京。弘康集团是一个由华人企业家创建的跨国企业，总部设在日本国京都中央区八重洲2—7—9，下属有9家独立的公司：     

中厚板平面形状控制中的GM-AGC系统

阐述了对中厚板平面形状控制系统的基本要求和提高中厚板成材率的关键技术内容,研究了中厚板平面形状控制ＧＭ－ＡＧＣ系统的基本结构,着重分析和研究了成形轧制阶段变截面轧制的控制特点,以及提高平面形状控制精度必须考虑的几个问题,对ＧＭ－ＡＧＣ系统应采用的改进措施。     

K 16Mn连铸坯热装炉轧制对轧材组织性能影舷

采用高温固溶加热法,在φ300轧机上模拟现场连铸坯热装炉轧制工艺,分别考察了K16Mn钢不同热装温度和开轧温度对轧材组织性能的影响.结果表明,热装轧制和常规冷装轧制屈服、抗拉强度相当,热装轧制成品塑性、韧性均较好.热装轧制工艺对K16Mn钢组织的影响,随着热装温度的提高,轧前奥氏体晶粒变得粗大,并且轧后组织混晶程度提高.这可通过提高开轧温度,首道次采用大压下量促使铸坯发生完全再结晶来消除.从而细化晶粒.改善成品组织性能.     

Electrophysiological research of synapse formation from beginning to maturity

The development of synapses is an important question in neurobiology. We employ patchclamp technique to record MEPCs and EPCs of myoballs inXenopus cell culture. The rate of EPC/MEPC is related with synapses maturation. Accordingly, we define the mature synapses as those whose rate of presynaptic membrane ’ s EPC to MEPC is more than 8. The process of maturation needs about 2–5 h after neuntes contact with myoballs. We divide the development of synapses into three stages: young, developing and mature. The neurotransmitters stack gradually and increase by hundreds of times along with young synapses growing into maturity. So the process of synapses maturation should include presynaptic membrane specialization, postsynaptic membrane specialization and neurotransmitters stack.     

Two tyrosines in CD3ε-ITAM are required to induce T lymphocyte apoptosis

CD3ε of T cell antigen receptor complex (TCR/CD3) plays an important role in the resembling of the complex and activation signaling through its conservative immunoreceptor tyrosine-based activation motif (ITAM) in the cytoplasmic tail. Previous study showed that a chimera molecule, consisting of the extracellular-transmembrane domain of human CD8α fused to the cytoplasmic domain of CD3ε, induced apoptosis of T lymphocytes, indicating that apoptotic signals were transduced through the CD3ε- ITAM. To elineate involvement of the two tyrosines in apoptotic signaling pathway, cDNAs with mutations at Y170F, Y181F and Y170F/Y181F in CD8-ε-ITAM were made by point mutation and PCR, and then cloned into pcDNA3 eukaryotic expression vectors. Stable expression cell lines were established after transfection of the expression vectors into CD8+- Jurkat T lymphocytes. Stimulation of these cell lines with anti-CD8 monoclonal antibody showed that only the cells with expression of wild type chimera CD8-ε died by apoptosis, but not those cells with expressions of mutated CD8-ε chimera, indicating that the two tyrosines in CD3ε-ITAM were required for the apoptotic signal transduction in T lymphocytes.     

Effect of calcium ions on the secondary structures of photosystemⅡ and its relations with photoinhibition

Calcium ions play an important role in the oxygen_evolving process of photosystem Ⅱ as demonstrated in many experiments. The changes of the secondary structures of PS Ⅱ induced by the depletion of Ca 2+ were reported. The results indicated that the removal of Ca 2+ led to the transition of α helix to turns and sheet structures. While Ca 2+ was re_added to the media, only the structures changed to turns could be recovered. The protein conformational changes of PS Ⅱ during the donor side photoinhibition induced by the depletion of Ca 2+ were also studied. This showed that the protein conformational changes differed between the control and Ca 2+ _depleted samples in a short period of illumination (within 10 min). However, the changes became similar when the illumination time was increased.     

Third-order optical nonlinearities for lanthanum (Ⅲ) complexes with 1,10-phenanthroline components

The nonlinear refractive indexes n 2 for the ethanol solutions of 1,10-phenanthroline (2.0×10 -3 mol·L -1), [bis(1,10-phenanthroline) lanthanum (Ⅲ)] nitrate (1.0×10 -3 mol·L -1), and [nitrato-fluoracil-bis (1,10-phenanthroline) lanthanum (Ⅲ)] nitrate (1.0×10 -3 mol·L -1) are first measured, the third-order nonlinear optical susceptibilities χ (3) and <γ> are calculated, and the mechanisms of the third-order optical nonlinearities enhanced by lanthanum (Ⅲ) are discussed preliminarily.     

Bio-rational design of photosystem Ⅱ inhibitors (Ⅰ)──Molecular modeling of cyanoacrylates and ureas in photosystem Ⅱ D1 protein of Pisum sativum

Molecular modeling of cyanoacrylates and ureas with D1 protein of Pisum sativum have been presented. Studies show that these two kinds of inhibitors occupy the similar region in the D1 protein. Cyanoacrylates have more binding sites than ureas, thus they have higher activities.     

（H,G）—变换和拟正则半群

研究一般的（Ｈ,Ｇ）型变换通过适当合成变换后生成拟正则半群;并建立了Ｇ－变换和（Ｈ,Ｇ）型变换两者之间的拟共形共轭关系．对于给定的一个拟正则半群,构造了一个不变共形结构ＧΓ,使得该半群中的每个元素在这个不变共形结构下保持Ｇ－变换不变．