《医学生物学》教学浅议

本文从如何激发学生的学习热情,克服他们心理对《医学生物学》的学习恐惧;如何提高教师的自身素质,顺利完成每次课的教学目标等角度来阐述对本学科的教学探讨,希望能对同行们提供一些帮助。     

中国纳米碳酸钙工业生产现状及应用

本文介绍了纳米碳酸钙的理化性能,分析了中国纳米碳酸钙生产现状及发展趋势,同时对纳米碳酸钙在精细化工中的应用作了概述.     

纳米科技大显身手

粘合剂和密封胶 国外已将纳米材料棗纳米SiO2作为添加剂加入到粘合剂和密封胶中,使粘合剂的粘结效果和密封胶的密封性都大大提高。其作用机理是在纳米SiO2的表面包覆一层有机材料,使之具有亲水性,将它添加到密封胶中     

打造"天梯"上九霄

纳米技术到底会为我们带来什么呢?下面我们举一个例子也许会让你获得一些感性认识。     

过度训练:不同发展阶段的神经内分泌变化

综述了关于过度训练状态下机体神经内分泌方面的变化,并对其中一些矛盾的结果提出了可能的解释。     

浅谈纳米光电子器件的发展现状

纳米光电子技术是一门新兴的技术，近年来越来越受到世界各国的重视，而随着该技术产生的纳米光电子器件更是成为了人们关汪的焦点。主要介绍了纳米光电子器件的发展现状。     

Science Letters： A synthetic Toll-like receptor 2 ligand decreases allergic immune responses in a mouse rhinitis model sensitized to mite allergen

It has been proposed that activation of Toll-like receptors （TLRs） plays crucial roles in the polarization of adaptive immune responses. A synthetic Toll-like receptor 2 （TLR2） ligand, Pam3CSK4, has been reported to modulate the balance of Th1/Th2 responses. We evaluated the modulation effect of Pam3CSK4 on allergic immune response in a mouse rhinitis model sensitized to house dust mite allergen （HDM）. Mice were sensitized and challenged with Dermatophagoidesfarinae allergen （Der f）, and then the allergic mice were treated by Pam3CSK4. Nasal allergic symptoms and eosinophils were scored. Der f-specific cytokine responses were examined in the splenocytes and bronchoalveolar lavage fluid （BALF）. Serum level of total IgE was also detected. After establishing a mouse allergic rhinitis model with HDM, we have showed that Pam3CSK4 treatment not only ameliorated the nasal allergic symptoms remarkably but also decreased the eosinophils and total inflammation cells in BALF significantly. Analysis of cytokine profile found that IFN-7 released from either BALF or stimulated splenocytes increased markedly in Pam3CSK4-treated mice, while IL-13 decreased significantly. Moreover, serum level of total IgE was significantly lower in Pam3CSK4-treated mice than in the untreated. Thus, in an allergic rhinitis mouse model developed with HDM, Pam3CSK4 was shown to exhibit an antiallergic effect, indicating its potential application in allergic diseases.     

基于Hamaker假设的黏着接触弹性模型

为研究微纳米系统中的黏着接触问题，基于Hamaker假设和Lennard-Jones势能定律，通过积分方法得到了球体与平面间的黏着力，同时结合经典弹性理论建立了一种新型的球体与平面黏着接触的弹性模型，该模型可以同时得到平面轮廓随间距的变形过程及黏着力和平面变形量随间距的变化规律，当球体半径较大时，所建模型与基于Derjaguin近似的黏着模型给出的结果基本一致，随着球体半径的逐渐减小，两种模型的差异逐渐增大，这是由于Derjaguin近似的误差随球体半径的减小而增大引起的，因此，当球体的半径趋近纳米级时，基于Hamaker假设的黏着接触模型可以给出更加准确的结果。     

形态学实验室管理的实践

为应对21世纪需求高质量、高素质综合型医学人才的时代要求。我院对实验教学作了大胆的改革和尝试,初步形成一套科学的管理体系和基础医学实验中心。运作绩效表明,该套管理体系和基础医学实验中心能很好实现实验室的资源共享。