H7N9疫情形势下野生动物保护工作的现状、问题及建议

简要概述了塘沽野生动物保护工作的发展现状,结合当下H7N9禽流感疫情形势,浅析野生动物保护和监测工作中所面临的热点、难点问题,按照天津市滨海新区"十二五"总体发展战略要求和布局,提出了改进措施和工作建议。     

向病毒宣战：防疫战线“双剑”出鞘

动物传染疫病的传播是全球性的,如果不严加控制,势必造成重大的经济损失,给人们的生活和身体健康造成巨大的影响.如:2004年,禽流感袭击了亚洲十多个国家,其他各种各样的动物源性疾病(如疯牛病、口蹄疫等)也不断在全球各地肆虐……     

Mutations in Hemagglutinin of a Novel Avian-Origin H7N9 Virus That Are Critical for Receptor Binding Specificity

A novel avian-origin H7N9 influenza virus was discovered in March in China and has caused a total of131 people infected including 39 deaths in China as of June 9, 2013. Adaptation of avian viruses to efficiently infect humans requires the viral hemagglutinin（HA） binding switches from avian to human type receptors with help of some mutations in HA. As such it is critical for pandemic assessment to discover these mutations as hallmarks of adaptation. To continue our previous study of this novel H7N9 virus, we identified two sets of mutations in HA. The first set of mutations are present in the current circulating strains of 2013 H7N9 in China, and the second set are potential mutations that were found when compared to the HAs of previous human H7 subtype. These two sets of mutations exhibited unique features. The first group of mutations, on average, enhanced the HA binding to human type receptors whereas reduced that to avian types. Further the reduction of avian binding was almost three times of the increase of the human binding. The second group increased the binding to both human and avian types.But the increase in human types was almost three times of that in the avian types. Though different in their way of changing the binding preference, these two sets of mutations both contained more mutations to decrease the avian binding and increase the human binding than those that did the opposite. Our research highlighted the pandemic potential of this novel virus by showing the important mutations that could potentially help it to adapt to human hosts. Our findings offered new insights into the current state of evolution of this virus, which might be helpful for the continued surveillance of the emergence of H7N9 strains having the ability of human-to-human transmission.     

自动喷雾小车

进入新世纪以来，全球先后爆发了包括“非典”、禽流感、猪流感等新型疾病，当这些疾病来临的时候。都需要大量的人力频繁进行消毒。这样不利于消毒人员的保护。     

一起高致病性离流感的诊断与防治

禽流感病毒具有高致病性和高致死率，它不仅给养殖业造成很大的危害，而且对人类的健康和生命安全也构成了威胁。近几年来，世界各地相继出现了感染禽流感病毒发病病例，蔓延迅速，病情较重，死亡率较高。根据流行病学调查，临床症状、病理解剖和实验室诊断。确诊了一起高致病性禽流感疫情，以提高人们对本病的认识。     

LBM2eHBc＋融合基因植物表达载体构建及对番茄的转化研究

禽流感病毒一直是家禽和家畜健康养殖的巨大威胁,甚至威胁着人类的健康,人们也一直在研究各种形式的疫苗来应对禽流感病毒的威胁. 番茄作为生物反应器应用于动物疫苗生产具有独特的优点,本研究优化了番茄子叶的再生体系,同时构建了LBM2eHBc+融合基因的植物表达载体并对番茄进行了遗传转化. 结果表明在玉米素(Zt)浓度为0.5 mg/L时番茄子叶外植体的芽再生率达到93.33%;测序结果证明植物表达载体pBI121- LBM2eHBc+构建成功;利用农杆菌介导的转化方法获得再生抗性苗34株,经PCR检测,阳性率为75.0%,本研究结果为进一步开发禽流感口服疫苗奠定了基础.     

珠海检验检疫局2项成果:创新结合实用

<正>珠海检验检疫局2项成果:创新结合实用近日,珠海检验检疫局主持承担的两项广东省科技厅科技近日,珠海检验检疫局主持承担的两项广东省科技厅科技计划项目"禽流感病毒珠海株的HA基因和NA基因序列分析及哺乳动物感染模型的建立"和"水产品中硫丹的快速确证方法及其在鱼体和环境中的残留消     

对水域中流感病毒的防控措施浅析

高致病性禽流感不仅给全球养禽业造成了巨大经济损失,严重危害养禽业发展,而且还对人类健康构成威胁。     

浅谈禽流感对人类健康与社会经济的影响

通过实地调查,分析禽流感对经济的直接和间接影响,同时对禽流感的预防控制提出了一些思考。     

注射H5N1亚型禽流感抗体鸡的血清抗体水平消长规律监测

为了解H5N1亚型禽流感纯化抗体(IgG)在鸡体内消长规律,用血凝抑制试验检测了不同注射时间分离的血清样品。结果表明IgG接种后第1至5天,血清抗体滴度恒定在24~26,第8天为23~24,第10天以后几乎检测不到抗体。上述数据表明注射滴度为29的抗体液1mL可有效保护肉鸡免受禽流感病毒的感染,有效期为8天。