Therapeutic applications of bone marrow-derived stem cells in liver transplantation for end-stage liver diseases

Today, liver transplantation (LT) is the only established treatment for end-stage liver diseases. The de- velopment of LT, including OLT, cadaveric LT, split LT, living donor LT (LDLT), brings hopes to patients with these diseases. However, increasing donor shortage, rejection and life-long immunosuppression with its side effects are the major limitations of this therapy strategy. Bone marrow-derived stem cells (BMDSCs) are capable of differentiating into hepatocyte-like cells and contribute to liver injury repair. The microenvironment of liver injury caused by rejection, ischemia/reperfusion, loss of liver mass, recurrence of HCV and "small-for-size syndrome" after LT can attract a variety of bone marrow-derived stem cell population to the peripheral circulation and then migration to the injury liver to promote the hepatic function restoration. Additionally, BMDSCs can also take part in the functional regeneration of living donor liver after LDLT. This participation in liver regeneration may be associated to the interac- tion between SDF-1and its receptor CXCR4, involving HGF, IL-8, MMP9, and VEGF/VEGFR-2. BMDSC with its bio-characteristics could maintain the allograft tolerance from different angles and in different ways. In conclusion, BMDSCs transplantation, as a new assistant therapeutic method for LT, will ex- pand the space of LT, and provide more survival opportunities for the patients suffering liver diseases in the future.     

DRM单频网规划与实现

DRM是频率在30MHz以下的数字广播系统,抗多径衰弱和干扰强,适合实现单频网,本文在DRM单频网仿真分析的基础提出了网络规划策略,描述了实现发射机时延校正方法.     

56例牙髓治疗后疼痛临床分析

目的:为提高对牙髓治疗后疼痛的防范认识.方法:对56例牙髓治疗后疼痛的病例进行临床分析.研究发现,引起疼痛原因有:25例牙髓炎未完全开髓,髓腔未能有效减压;8例临床误诊,对慢性根炎周炎急性发作,无通根治疗压力未减;16例塑料化治疗适应症掌握不严;4例干髓治疗有2例并发残髓炎,2例继发根炎尖;3例根管治疗器械折断未取出而充填.结论:牙髓治疗后疼痛原因是多方面,只有术前全面观察,正确的临床诊断,严格掌握适应症,术中采取规范有效的治疗措施,才是减少牙髓治疗后疼痛的有效措施.     

高校图书馆的阅读治疗服务对大学生心理健康的作用

分析了大学生产生心理疾病的原因,探讨了"阅读治疗"对大学生心理健康的作用,提出了高校图书馆开展阅读治疗的措施。     

治疗癌症的重粒子加速装置

重粒子是指1个原子核或者几个的介子,同电子、中子和质子相比,质量更大,所以称为重粒子,也叫作重子。所使用的重粒子是氦、碳、氖、硅和氩等已被离子化的原子核。 灭癌是人类的宏愿,过去在寻找治病的方法中,除了早期切除和服抗癌药物之外,还研究了BRM(生物反应修改)、温热疗法、X射线—γ射线辐照等     

漫谈老年高血压病的临床特点及治疗

本文对老年高血压的特点及其治疗问题作了比较详细叙述。