乙胺碘呋酮转复律心房纤颤92例临床分析

报告了应用乙胺碘呋酮治疗心房纤颤92例的转复情况。     

心房晚电位的检测与分析系统

介绍了一种基于微机的心房晚电位的检测与分析系统，通过对Ｒ波触发和Ｐ波触发的信号平均心电图方法的讨论和比较，获得了一套实用可行的Ｐ波提取方法，标准Ｐ波宽度，空间向量的总Ｐ波宽度和最后３０ｍｓ均方根电压是一些与房颤关联的诊断参数，详细的介绍了本系统获取这些参数的算法，并给出了一套辅助临床诊断的参考指标，初步使用的情况表明，这个系统的检测答方法是有效的，在临床上可以对房颤和房扑进行预测，目前国内对心房晚     

脑中心房肽基因的表达及盐负荷与脱水对它的影响

心房肽(Atriopeptin,心房利钠肽Atrial Natriuretic Peptide,ANP)是首先自心房中分离纯化的肽类激素,具有舒张血管、促进水盐排出维持体液平衡等重要作用。后来经免疫组织化学等方法证实,部分心房外器官如心室、肺、脑、肾、脾等组织中也有心房肽,但不能完全排出组织中心房肽来自血液循环。只有用分子杂交法证实组织中有心房肽基因转录产物,才能确切肯定该组织是心房肽产生器官。迄今为止对影响心房肽基因表达、心房肽合成和分泌的因素,仍有待进一步阐明,特别是脑组织中心房肽情况所知甚少。本文报道互补RNA探针的制备及用分子杂交法证实脑是心房肽产生器官,并且水盐平衡显著影响它的心房肽基因表达。     

心房纤颤治疗新进展

房颤是一种常见的心律失常，其发病率随年龄的增加而升高，目前高血压、冠心病已逐渐成为老年房颤的最常见原因，现已公认房颤与脑卒中有很大关系，所以房颤病人进行转复治疗尤其抗凝治疗具特殊意义。在抗凝治疗过程中，应结合患者的年龄、临床危险因素及抗凝治疗的益处和潜在危险，合理使用抗凝药物。抗凝治疗有预防栓塞的作用，从而能显著降低卒中的发病率     

共同心房并二尖瓣前瓣裂及左上腔畸形引流至冠状脉窦的手术矫治术

１临床资料病儿，女，１４岁，自幼发现心脏杂音，诊断为先天性心脏病。易感冒并发肺部感染。体格检查：发育较一般同龄人差，颜面轻度紫绀，颈静脉怒张不甚明显。心前区有抬举样搏动，心界扩大，无震颤。胸骨左缘２－４肋听到三级以上全收缩期粗糙的杂音，杂音不向左腋下传导。肺动脉瓣第二音亢强分裂，吸气时增强，呼气时减弱。Ｘ线胸片示：正位片明显肺充血，肺动脉段膨隆向左下延伸，心尖圆钝、翘起，心界向左扩大，心胸比大于０－５２。侧位片显示：心前间隙消失，心后缘与脊柱重叠。心电图：窦性心律，心电轴左偏（－６０°），左右心…     

Prediction of ventricular fibrillation based on nonlinear multi-parameter

Ventricular fibrillation (VF) caused by myocardial ischemia is one of the leading factors of death attributed to cardiovascular diseases. It is particularly significant to predict VF and gain valuable time for clinic therapy. Five dogs are taken as the research objects and a VF model is introduced. The nonlinear characteristics of the ECGs before and after VF are investigated with nonlinear multi-parameter analysis methods, Gaussian kernel (GK) correlation estimation algorithm and Lyapunov exponent estimation algorithm. Correlation entropy h2 is also presented. The results indicate that there are three parameters which will change at the same time with the conditions of myocardial ischemia,and any changes of a single parameter may be caused by other factors and mislead the judgment. Multi-parameter analysis is more reliable to reveal the heart conditions, and to predict VF without misjudgments.     

Ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation

Objective: to evaluate the efficacy and safety of ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation. Methods: The study population consisted of 9 patients with 5 males and 4 females enrolled consecutively who had idiopathic paroxysmal atrial fibrillation(AF). The ultrasound balloon was positioned through a special sheath to the orifice of the target vein by a transseptal procedure. The balloon was inflated with contrast-mixed saline (contrast:saline = 1:4) whose volume was decided by the diameter of the target pulmonary vein. The ablation energy was usually set up at 35 to 40 watts with temperature controlled at 60 degrees C. The duration of each ablation was about 120 seconds which was repeated not over 10 times. Results: The average duration of the total procedure was 132+/-68 min for our patients. The average fluoroscopy time was 33+/-17 min. With a mean follow-up of 16+/-8 months after the procedure, AF was completely eliminated in 4 patients without antiarrhythmic drugs. The episodes of atrial fibrillation were eliminated in 2 patients with low dosage of oral amiodarone (0.1, once daily) which was ineffective before the procedure. The frequency of episodes was similar to that before the procedure in 3 patients. There were no complications such as hemopericardium, air embolism and stenosis of the pulmonary veins by angiography, related to the procedure. Conclusion: Ultrasound ablation of the pulmonary veins is a new approach to treat paroxysmal atrial fibrillation. Before we determined its value, we need to do more researches with bigger sample, randomization and comparison design.     

心脏内分泌研究的进展

心脏除具有“动力”功能外,近年来,科学家证实心脏亦有内分泌功能——分泌心房肽等。心房肽具有很强的利钠、利尿作用;血管扩张作用;参与免疫调节和调节脑屏障作用等。心脏内分泌功能的发现,对心脏功能的研究开辟了崭新领域,对传统的内分泌学说提出了新观念。     

心房纤颤转律的评价：附60例临床和超声心动图分析

本文对60例 Af 自然转律或主动转律者进行对比分析。结果显示:左房内径正常者多为阵发性 Af,而左房增大者以持续性 Af 者多见;阵发性 Af 者大多数心功能正常。在病因方面,冠心病与风心病比较,前者以阵发性 Af 更多见,易于转复,后者易发展为永久性 Af。左房内径正常的17例全部转律,而左房内径增大的则有8例发展为永久性 Af,但左房增大的程度与转律似无明显关系。