β—紫罗兰酮合成研究

改进了β－紫罗兰酮的合成方法，并研究影响反应产率诸因素，结果表明：在适当条件下，β－紫罗兰酮总收率可达５２％。     

脂肪醇氧化制取脂肪醛

利用混合脂肪醇减压蒸馏获得的 C_8、C_9、C_(10)、C_(11)醇,在电解银催化剂存在下,氧化制取相应脂肪醛。研究了反应条件对转化率、选择性和收率的影响。转化率、选择性达到了90%以上。     

用蛋白质二硫键异构酶研究人胰岛素原二硫键的重组

蛋白质二硫键异构酶(PDI,Protein Disulfide lsomerase)是一种亚基分子量为57kD的二聚体蛋白,它催化蛋白质巯基和二硫键的交换反应,一般认为它参与细胞内蛋白质天然二硫键的形成。我们曾用PDI研究过胰岛素A,B链的重组,在合适的条件下,PDI使二硫键错接的胰岛素或S-磺酸型胰岛素A,B链以25—30％的产率生成胰岛素,以及使S-磺酸型Al-B29交联胰岛素以90％的产率生成含有天然二硫键的交联胰岛素。尽管还原的胰岛     

邻苯二甲醛作为固氮酶活性中心双齿配体的研究

考察了邻苯二甲醛对固氮酶催化乙炔还原及放Ｈ２活性的影响。结果表明邻苯二甲醛是有效的固氮酶活性中心双齿螯合抑制剂。在ＭｏＳ＾２－４－ｎＦｅＣｌ２－ＤＭＦ自兜合成固氮酶活性中心模拟物体系中，邻苯二甲醛的加入导致线型三核络合物［Ｃｌ２ＦｅＳ２ＭｏＳ２ＦｅＣｌ２］＾２－（低维结构）的特征电子吸收光谱消失。本文进一步讨论了在此双齿配体协助下上述无机盐体系自兜合成高维结构Ｍｏ－Ｆｅ－Ｓ簇化合物的可能性。     

TQ-206馏分中丁烯醛的分离

本文从两方面初步探讨了TQ—206馏分中丁烯醛的分离及提纯对于工业上资源的再利用有很重要的意义.这里我们介绍两种方法:物理方法和化学方法.     

生物吸收性合成聚酯纤维晶体模型的描绘

生物吸收性合成聚酯纤维常用作外科手术缝合线。这种合成可吸收缝合线(SAS)优于非生物降解的天然和合成材料,它们在体内是通过水解降解成为无毒产物并最终为组织吸收。在降解过程中,材料的结晶度对合成可吸收缝合线水解降解过程的影响是很重要的。本文通过对微原纤晶体结构模型和Swiss—Cheese晶体模型的描述,对几种SAS在降解过程中结晶度、降解性能和力学性能的变化进行了阐述。     

一个极限定理与非线性对偶规划的最优判别及存在性

Rockafellar在文献[1]中应用共轭函数与扰动函数建立了新的一般性的凸对偶理论。在这一理论的影响下,近几年来许多作者在一些广义凸或其他特殊类型的非凸对偶规划方面,取得了若干重要的结果。本简报主要是针对一般的非线性规划,给出它的对偶规划(极小极     

Interaction of catechins with aluminum in vitro

Tea is one of the most popular beverages, consumed by over two thirds of the world's population; but the aluminum accumulation property of tea plant is becoming the focus of many researches because of aluminum's known adverse effect on human health. Investigation of the interactions of catechins with Al(3+) showed that during the interaction of catechins with Al(3+), the UV-vis spectrum of catechins was changed. Absorption of EGCG at 274 nm decreased and increased at 322 nm; EC and C's at 278 nm changed little. The ratio of Al(3+) to EGCG was 1:1 in pH 5.0 buffer solution; in pH 6.2 buffer solution, the ratio in the Al-EGCG complex was 1:1. Interestingly, while the ratio reached to over 2, after the complex of Al-EGCG started polymerization, the ratio in the polymer was 2:1. In pH 6.2 buffer solution, the complex behavior of C with Al(3+) was the same as that of EGCG, with a little difference for EC. When the ratio of Al(3+) to EC was <1, the complex in ratio was 1:2, but, the complex polymerized when the ratio of Al(3+) to EC was >1. It was found that the ratio of Al(3+) to EC in the polymer was 1:1. Polymerization of Al-catechin complexes might reduce aluminum absorption in the intestine. Kow value was also employed to study the properties of aluminum species in tea infusion (at gastric and intestine pH condition) and the effect of catechins and tea polyphenols on Kow in buffer solution. Results showed that Kow value rose much higher at the intestine pH than at the gastric pH. Tea polyphenols and catechins could greatly reduce aluminum Kow value in acetic buffer, indicating that these compounds may reduce aluminum absorption during tea intake.     

打朔迷离的起重机专利侵权“连环案”

2002年12月20日,一起扑朔迷离的起重机专利纠纷连环案,从行政调处到司法起诉,从县法院到省高院,从省知识产权局到国家知识产权局,辗转四年后,经河南省郑州市中级人民法院审理后作出一审判决:被告开封市兰考县新原机械厂停止侵权,销毁已生产的"全自动液压起重机"专利侵权产品,并赔偿原告兰考县永昌机械厂经济损失2万元.至此,这起历时4年,在侵权认定和审理中难度均创河南省专利侵权案件之最的"起重机"专利侵权连环案,终于告一段落.