两类重要的(α,β)-度量之间的射影等价

找到了一组方程去刻画(α,β)-度量F=α+εβ+β2/α(ε为常数)与Randers度量F=α+β之间的射影等价,其中α和α是两个黎曼度量,β和β为流形上的两个非零的1-形式.     

Na~+导电陶瓷的交流阻抗谱

以β″-Al₂O₃导电陶瓷为电解质,研究制备银/碳毡/低熔点钠盐电极（Ag/C/（NaNO₃+NaNO₂））,并选择银电极作为对比电极。测试条件为:温度275～400℃、频率12～10⁵ Hz。采用交流阻抗谱法（Ac）进行β″-Al₂O₃导电陶瓷与金属Na⁺界面兼容性和界面离子传导机理研究。结果表明:β″-Al₂O₃导电陶瓷的电导与温度关系服从于阿仑尼乌斯公式。比较两种电极可以发现,电极/电解质的界面接触对电极/电解质界面迁移阻抗和阻抗谱测试结果会有较大程度的影响。     

脑血管病患者的脑电图,诱发电位TCD与CT对比研究

目的：比较脑电图、诱发电位、脑彩超及CT在诊断脑血管病中的作用。方法：将100例病人分成TIA组,腔隙梗塞组脑梗塞组及脑出血组。分别进行脑电图、诱发电位、脑彩超及CT检查。结果：CT检查TIA阳性率最低,仅4％,对脑电图、诱发电位、TCD三者检查结果比较,异常率依次为诱发电位＞脑彩超＞脑电,诱发电位检测TIA意义最大。结论：电生理检查对脑血管病的检测有相对特异性、敏感性及重要性,是脑血管病早期诊断的重要手段之一。     

微波辐射β分子筛负载SO_4~(2-)/Fe_2O_3固体超强酸催化制备2-(2-1H-苯并咪唑基)-苯酚

以邻苯二胺和水杨酸为原料,β分子筛负载SO2-4/Fe2O3固体超强酸催化剂,微波辐射促进合成了2-(2-1H-苯并咪唑基)-苯酚。实验结果表明:n(水杨酸)∶n(邻苯二胺)=1.0∶1.1(水杨酸6.90 g,邻苯二胺5.70 g),固体超强酸相对用量0.10 g,微波辐射功率500 W,微波辐射时间5 min。产率达87.8%,与常规加热方法相比,具有反应速度快、转化率高等优点。     

β-Catenin和Wnt5a蛋白在人牙齿早期发育过程中的表达

以人牙胚为材料,运用免疫组织化学染色技术分别检测经典Wnt信号通路的β-Catenin和非经典Wnt信号通路的Wnt5a的表达模式．结果表明：从12w人牙胚帽状期到15w钟状期。β-Catenin蛋白在牙上皮细胞的表达强于牙问充质细胞,且其在磨牙细胞的表达强于门牙;随着发育的成熟,β-Catenin蛋白在内釉上皮细胞的表达增强,而在外釉上皮层和星网状层的表达降低．WntSa蛋白在人牙胚中的牙间充质细胞的表达强于牙上皮：从帽状期到钟状期．Wnt5a蛋白在内釉上皮层和星网状层的表达降低,β-Catenin蛋白的表达整体明显高于WntSa．因此,经典Wnt信号通路在人牙齿早期发育过程中发挥重要的作用．     

集值映射与层型结构空间(英文)

本论文利用半连续集值映射的插入给出具有层型结构空间的一些等价刻画.也引入了K-lower和K-upper集值映射,利用此概念给出了k-半层空间以及k-MCM的刻画.     

α,β-不饱和酰胺TRPV1抑制剂的Topomer CoMFA模型

利用SYBYL软件中的Topomer CoMFA方法分析了α,β-不饱和酰胺类TRPV1抑制剂的三维定量构效关系(3D-QSAR)模型.分子被分开为羰基和氨基两个基团,在Topomer CoMFA模型考察了立体场和静电场对抑制活性的影响.结果显示:去一交叉验证的相关系数q2为0.702,模型的预测相关系数r2为0.881.说明所建立的模型在统计上有较好的稳定性和预测能力,有助于TRPV1抑制剂的研发.     

Silk Fibroin Microspheres： Preparation and Application for Controlled Drug Delivery

Silk fibroin （SF）, a natural protein polymer, has several unique properties such as aqueous processability, biocompatibility, and biodegradability. Due to these advantageous properties, it is promising for applications in various fields, especially drug delivery. In this paper, the simple preparation of SF microspheres was discussed via self-assembly. Some of SF＇s physicochemical properties and morphology were also investigated. The results show that the morphology, size and size distribution of silk microspheres depend upon various processing parameters, especially including volume ratios among SF, ethanol and polyvinyl alcohol （PVA）. Regular silk microspheres were obtained in PVA solution when adjusting the volume ratios of silk to ethanol from 20：1 to 20： 9. We also found that SF microspheres with various appearances were formed by addition of different PVA solution concentrations under a constant silk solution to ethanol volume ratio. From the Fourier transform infrared spectroscopy（FTIR） of silk microspheres, it was found that introducing ethanol into the SF solution induced conformational change from random coil to β-sheet. Additionally, under the observation of scanning electron microscopy （ SEM）, the shape of self-assembled silk microspheres was determined to be spherical. Finally, SF＇s potential as drug delivery carriers was discussed in the experimental results.     

Induction of human β-defensin-2 in airway epithelial cells by Streptococcus pneumoniae： involvement of IP3-dependent intracellular calcium release and NF-κB

Human β-definsin-2 （hBD-2） is mainly induced by bacterial factors and pro-inflammation mediators in epithelial cells. As the major cause of community-acquired pneumonia, whether Streptococcus pneumoniae （S. pneu-moniae） stimulation induces hBD-2 expression in airway epithelial cells is elusive. In this study, we found that S. pneumoniae stimulation induced hBD-2 expression in a time-and concentration-dependent manner in primary human airway epithelial cells. To further reveal the mechanism of S. pneumoniae inducing hBD-2, we found that S. pneumoniae stimulation activated NF-κB signaling pathway. Specific NF-κB inhibitor, PDTC, could reverse the induction of hBD-2 by S. pneumoniae. We also found that cellular inner Ca^2＋ signaling is involved in the S. pneumoniae-induced hBD-2. Taken together, our find-ings indicated that S. pneumoniae can stimulate the expression of hBD-2 in airway epithelial cells and NF-κB and inositol triphosphate-dependent intracellular calcium release is involved in this induction.     

NCEP结合GPS技术在地震分析预测中的应用初探--以日本北海道2003.9.26Ms8.1地震为例

首次试用NCEP(美国国家环境预测中心)全球再分析资料结合GPS(全球定位系统)监测数据对日本2003年9月26日Ms8．1级地震进行了综合分析。结果表明：此新方法能够有效地反映临震地面红外异常增温,增温异常区域与GPS监测到的日本板块运动最大速率部位基本吻合,表明红外增温异常与区域地壳相对加速活动有关,两者结合是一种短期临震前兆探测的较好方法。