三角域上的Wang-Ball曲面带形状参数的扩展

为了扩大自由型曲面的选择范围,本文引入一个形状参数,给出了三角域上Wang-Ball曲面的扩展。通过改变形状参数的值,可以调控曲面的形状。形状参数几何意义是明确的,随着参数的增大,曲面向控制网格靠近。     

wM1空间

本文定义M,空间的一种弱变种,称为ωM_1空间,通过对这些空间的研究将有助于回答M_1是否等价于M_3的问题。     

The role of apolipoprotein E in lipid metabolism in the central nervous system

The critical roles of apolipoprotein E (apoE) in regulating plasma lipid and lipoprotein levels have been extensively studied for over 2 decades. However, an understanding of the roles of apoE in the central nervous system (CNS) is less certain. This review will summarize the available experimental results on the role of apoE in CNS lipid homeostasis with respect to its modulation of sulfatide trafficking, alteration of CNS cholesterol homeostasis and apoE-induced changes in phospholipid molecular species in specialized subcellular membrane fractions. The results indicate that apoE mediates sulfatide trafficking and metabolism in the CNS. Moreover, although apoE does not affect the cholesterol mass content or the phospholipid mass levels and composition in the CNS as a whole, apoE modulates cholesterol and phospholipid homeostasis in selective subcellular membrane compartments. Through elucidating the roles of apoE in CNS lipid metabolism, new insights into overall functions of apoE in neurobiology can be accrued ultimately, leading to an increased understanding of CNS lipid metabolism and the identification of novel therapeutic targets for CNS diseases.Received 9 January 2004; received after revision 28 February 2004; accepted 10 March 2004     

浅谈宋代御史台的督察职能及历史作用

御史台是我国古代封建国家的重要监督机构。宋代御史官是皇帝的耳目，由皇帝亲自任命，其职责是纠察官邪，肃正纲纪。御史对宰相百僚在重大活动、科举考试、司法过程、行政事务、日常着装、行为规范等方面实施有效的督察，更进一步加强了专制主义中央集权，巩固了国家的统一，维护了赵宋王朝的统治，使宋代社会出现了一个相对稳定的局面，这对社会生产和经济文化的发展也是极为有利的。     

欧美技术创新政策比较分析

政府技术创新政策对于一国的技术创新能力和经济发展的具有重要的作用。比较分析了美国、英国、法国、德国政府的技术创新政策的宏观导向及其作用领域、决策的目标和支持措施，这对我国制定技术创新政策具有一定的借鉴作用。     

gcc/g++下C/C++和汇编的接口

汇编语言是低级语言,与硬件和操作系统紧密联系.它能够完成许多其他语言所不能完成的功能.笔者较详细地分析了在Linux平台的gcc/g 开发环境下,汇编程序与调用它的C/C 程序的接口约定.     

（f，g）-反演的函数方程的通解

马欣荣建立了迄今为止广泛的一对反演公式(f,g)-反演,它完全取决于所给的一对函数f,g是否满足函数方程g(a,b)f(x,c)-g(a,c)f(x,b) g(b,c)f(x,a)=0。本文就f,g为多项式和无穷级数时给出了上述方程的通解。     

框架——桩筏基础空间共同作用机理

将上部结构、基础与地基三者视为统一整体,上部结构考虑空间框架形式,筏板计算采用亨奇中厚板８节点等参数单元,桩土体系采用剪切位移法,考虑群桩效应进行共同作用的空间分析并编制了相应的程序。采用的方法是一种空间分析方法,可推广到框筒及框－剪结构的空间分析,在求解时利用波前法使得效率极大提高,所编制程序具有一定通用性,适用于工程实践。     

具有间断映象的隐变分不等式

在本文中，我们对一类隐变分不等式和广义隐变分不等式证明了几个解的存在性定理，其中所涉及的映象不需要有任何连续性质，这些定理改进和推广了Ｄｉｎｇ－Ｔａｒａｆｄａｒ，Ｙａｏ－Ｇｕｏ和其他人的某些最近结果。     

Butyrate-induced reactivation of the fetal globin genes: A molecular treatment for theβ-hemoglobinophaties

The inherited -hemoglobinopathies (sickle cell disease and thalassemia) are the result of a mutation in the adult () globin gene. The fetal globin chain, encoded by the globin genes, can substitute for the mutated or defective globin chain, but expression of the globin gene is developmentally inactivated prior to birth. Reinducing expression of the normal fetal globin genes is a preferred method of ameliorating sickle cell disease and the thalassemias. Stimulation of as little as 4–8% fetal globin synthesis in the bone marrow can produce >20% fetal hemoglobin in the peripheral circulation, due to enhanced survival of red blood cells containing both sickle and fetal hemoglobin, compared to those containing sickle hemoglobin alone. Butyric acid and butyrate derivatives are generally safe compounds which induce fetal hemoglobin production by stimulating the promoter of the fetal globin genes. An initial trial with the parent compound, delivered as Arginine Butyrate, has demonstrated rapid stimulation of fetal globin expression to levels that have been shown to ameliorate these conditions. Phase 1 trials of an oral butyrate derivative with a long plasma half-life have just begun. These agents now provide a specific new apporach for ameliorating these classic molecular disorders and merit further investigation in larger patient populations.