植物病原细菌的细菌素与细菌性病害的防冶

本文介绍了细菌素的一般性状,化学性质、遗传学基础及其在植物细菌性病害防治中的应用,探讨了细菌素在防病实践中存在的问题及解决途径。     

1949年以前中医舌诊学术发展历程的探究

宋以前虽然有关于疾病中舌部症状的描述,但并没有形成舌诊.金代,舌苔异常被作为伤寒病中一个具有辨证意义的主症,奠定了舌诊的基础.元代出现的舌诊专著是为了证明当时的外感病新学说"火热论"而建立的诊断方法.但是,在很长一段时间内,研究舌诊的医家们却力图用已经成为外感病治疗模式的六经辨证来研究、发展舌诊.直到温病学派成熟,建立了卫气营血辨证的舌诊方法后,外感病舌诊才从六经辨证的束缚中解放出来.舌诊得以从诊断外感病扩展到诊断内伤病,理论环节是建立了舌的脏腑分部学说,技术环节是确立了舌色与脏腑、气血、津液之间的联系.这一学术转化在清末完成.清末与民国时期,舌诊被作为中西医汇通的典范,进行了较深入的研究.中西医汇通学派的研究对舌诊的推广和应用起到了十分重要的作用.     

弱膨胀土铁路路基工程病害的防治措施

结合洛湛铁路路基施工的实例,从弱膨胀土可能出现的各类病害入手,根据弱膨胀土的工程特性和病害产生的原因,提出了弱膨胀土铁路路基工程病害的防治措施和处理方法。     

现代生活方式与休闲健身运动

本文探讨了现代社会的发展对人类生活方式产生的影响,讨论了休闲健身运动在现代生活中的重要地位,作者以现代科学技术的发展与现代文明病的产生之间的相互关系为着眼点,分析现代人对休闲健身运动的心理需求,阐述休闲健身运动对人的身心健康所起的平衡、调节和促进作用。     

MCTD、SS和RA患者血清中SARS-CoV抗体阳性原因分析

为探讨严重急性呼吸综合征(SARS)冠状病毒(SARS-CoV)抗体在SARS病原学诊断中的特异性及其在干燥综合征(SS)、混合结缔组织病(MCTD)和类风湿性关节炎(RA)患者血清中的假阳性问题，应用酶联免疫吸附试验(ELISA)和间接免疫荧光法(IFA)检测了111例正常对照和46例SS、MCTD和RA患者血清中SARS-CoV抗体的阳性率。结果在正常对照和SS、MCTD和RA患者中，应用ELISA测定SARS-CoV抗体的阳性率分别为3．6％(4／111)和19．6％(9／46)，经IFA检测，上述SARS-CoV抗体阳性者均为阴性。提示IFA诊断SARS的特异性为100％，ELISA诊断SARS存在一定的假阳性。     

33例肝脏良性肿瘤及瘤样病变的诊断及治疗

为探讨肝脏良性肿瘤及瘤样病变的临床特点和诊治。回顾性分析总结10多年来高校教工查体并收治的33例肝脏良性肿瘤及瘤样病变的临床资料。共行各种肝脏叶段切除术17例,未发生并发症和手术死亡。全面了解肝脏良性肿瘤及瘤样病变的临床表现,做好各种术前检查（如B超、CT、MRI、AFP）,结合病史综合分析。有助于明确诊断及合理治疗。     

Protein flexibility: its role in structure and mechanism revealed by molecular simulations

Computer simulations at the atomic level have arrived at a stage where they provide realistic modeling of flexibility in proteins (and the mobility of their associated solvent) that is important in understanding the nature of molecular motions. This can now be extended to the molecular and atomic motions that are associated with protein mechanisms. Moreover, the derived data agree reasonably accurately with experimental measurements of several kinetic and thermodynamic parameters. Fundamental insights emerge on the roles that this intrinsic flexibility plays in the thermodynamic characteristics of macromolecules in solution; these equip the investigator to probe the consequences of cognate interactions and ligand binding on entropy and enthalpy. Thus simulations can now provide a powerful tool for investigating protein mechanisms that complements the existing and the emerging experimental techniques. Received 29 May 2005; received after revision 23 August 2005; accepted 21 October 2005     

Prion: the chameleon protein

From Creutzfeldt-Jakob disease (CJD) to variant CJD through Gerstmann-Str?ussler-Scheinker syndrome, kuru and fatal familial insomnia, the journey leading to current understanding of the basic aspects of human prion diseases has been full of unexpected, but often dramatic and always fascinating twists. Recent progress in modeling prion diseases and characterization of the various prion protein forms reveal that such a wide spectrum of the diseases is associated with the chameleon-like conformational features of prions.     

古交屯村隧道病害原因分析及整治设计

介绍了屯村隧道的概况,阐述了隧道病害的类型及特征,在对该隧道病害原因进行分析的基础上,提出了对病害的整治措施。