水稻表观遗传的研究进展

从DNA甲基化、组蛋白修饰的形成条件及其作用机制等方面,对表观遗传学的一些常见的发生机制进行了简要综述,并对表观遗传在水稻中研究的前景作了展望．     

大鲵鸣叫语图的初步分析

对我国特有两栖动物大鲵的自然鸣叫和电刺激中脑诱发鸣叫进行录音，然后回放至语图仪进行窄带语图分析。结果显示不同状态下的鸣叫在频率、能量和谐波方面均存在差异。     

The conformation alteration of mouse hepatic histones after reacting with nicotine in vitro

UV differential spectroscopy, fluorescence spectroscopy and circular dichroism (CD) spectroscopy assays have been applied to studying the conformation alteration of mouse hepatic histones H1 and H3 after reacting with nicotine in vitro. The results indicate that their conformation changes from regular form to random form with the increasing reaction dose of nicotine. The adduction of nicotine or its metabolites with histones H1 and H3 accounts for the conformation alteration. Nicotine may affect the structure, function and expression of genes of chromosome by changing the conformation of histones.     

NuA4复合体及其在细胞内的功能

NuA4复合体是进化中非常保守的多亚基复合体。在真核生物中，NuA4复合体及其同源复合体广泛参与了基因转录激活、DNA损伤修复、细胞周期、糖代谢等重要的细胞生理过程。由于NuA4复合体具有乙酰化组蛋白H4／H2A和激活转录的能力而被人们广泛研究。对NuA4及其同源复合体组成和功能方面的研究进行简要介绍。     

QUEUEING NETWORKS WITH STRING TRANSITIONS OF MIXED VECTOR ADDITIONS AND VECTOR REMOVALS

1 IntroductionProduct form queueing networks have regained considerable interest over the last coupleof years. In particular, extensions beyOnd the wellknown JaCkson, BCMP and KellyWhittletyPe networks (e.g., I1--5]) have been establlshed. Extensions include networks with batchmovements (such as [6--10]), networks with negative customers and signalling ([11--17l, amongothers), and assemblytransfer networks ([18, 19]). Transitions ill product form netWOrs nowgeneral1y include multiPle sta…     

多糖的化学修饰研究进展

引用41篇文献介绍了多糖的化学修饰技术,综述了硫酸化多糖、硒硫酸酯多糖和硒化多糖的制备、纯化与分析研究进展.     

Automatic prediction of protein function

Most methods annotating protein function utilise sequence homology to proteins of experimentally known function. Such a homology-based annotation transfer is problematic and limited in scope. Therefore, computational biologists have begun to develop ab initio methods that predict aspects of function, including subcellular localization, post-translational modifications, functional type and protein-protein interactions. For the first two cases, the most accurate approaches rely on identifying short signalling motifs, while the most general methods utilise tools of artificial intelligence. An outstanding new method predicts classes of cellular function directly from sequence. Similarly, promising methods have been developed predicting protein-protein interaction partners at acceptable levels of accuracy for some pairs in entire proteomes. No matter how difficult the task, successes over the last few years have clearly paved the way for ab initio prediction of protein function.Received 26 March 2003; received after revision 15 May 2003; accepted 12 June 2003     

不同晶型分散染料受热凝聚性能研究

本文用圆盘离心式微粒粒径测定仪测定了分散深蓝H-GL,分散大红S-BWFL不同晶型染料悬浮液在模拟染色条件下染料颗粒粒径的变化,发现染料的不同晶型有不同的受热凝聚性能,而且悬浮液内所用的分散剂对受热凝聚性能也有较大的影响。