攻击的遗传学基础研究

同人类的许多行为一样，攻击具有遗传学基础．随着行为遗传学的兴起，研究者主要运用双生子研究与收养研究模式对攻击的遗传机制进行了大量研究，发现攻击，特别是严重的或终生持续的攻击或反社会行为具有明显遗传性；遗传与环境在攻击发生发展中具有交互作用，消极环境因素在高攻击性遗传危险的个体身上效应更大，攻击或暴力遗传危险使处于不利环境中的个体更可能出现攻击与反社会行为．这些研究发现对攻击干预具有重要实际价值．本文最后提出了在理解和解释遗传对人类攻击的作用时需要注意的几个问题．     

探讨获得性遗传

文章总结了前人所作的具有重大意义的有关获得性遗传的研究并探讨了其分子机制.     

探讨《遗传学实验》教学对学生素质的培养

新形势下如何利用有限的资源来培养"素质型"人才,是教育工作者值得研究的一个问题。作者结合目前《遗传学实验》存在的种种弊端,对实验的教学方法、让学生参与实验的准备以及改进实验考核方法等方面进行了改进,旨在为通过《遗传学实验》如何培养创新型人才做了一些探索、实践。     

ISSR分子标记技术在作物遗传育种中的应用

ISSR标记技术是在SSR基础上发展起来的一项新的标记技术,其引物设计简单,多态性高,重复性好,无需知道两端的碱基序列,信息量大,已在植物的遗传作图、种质鉴定、基因定位、遗传多样性等研究方面得到应用.本文对ISSR技术的原理和特点及其在作物遗传育种领域的应用进行了综述.     

Insights into the genetic basis of congenital heart disease

Cardiovascular malformations are the most common type of birth defect and result in significant mortality worldwide. The etiology for the majority of these anomalies remains unknown. Advances in the characterization of the molecular pathways critical for normal cardiac development have led to the identification of numerous genes necessary for this complex morphogenetic process. This work has aided the discovery of an increasing number of single genes being implicated as the cause of human cardiovascular malformations. This review summarizes normal cardiac development and outlines the recent discoveries of the genetic causes of congenital heart disease. Received 4 November 2005; received after revision 14 January 2006; accepted 1 February 2006     

Focal and segmental glomerulosclerosis

An increasing cause of end-stage renal disease is the pathological lesion focal and segmental glomerulosclerosis (FSGS). FSGS is characterized by proteinuria and frequently nephrotic syndrome with ensuing renal failure. The etiology remains unknown in the majority of individuals. The idiopathic form of FSGS is most common; however, secondary forms of FSGS do exist. There is a form of FSGS that is fulminant that frequently recurs after renal transplantation with an estimated frequency of approximately 30%, suggesting that the pathogenesis is not solely a result of intrinsic kidney disease. Recently, hereditary forms of the disease were recognized as well as those associated with other congenital syndromes. Known genetic causes of the hereditary form of this disease have been suggested to account for upwards of 18% of cases. This review will address recent discoveries of the genetic mechanisms of hereditary FSGS and the current interpretations of their interactions at the slit diaphragm. Received 17 April 2006; received after revision 23 May 2006; accepted 6 July 2006     

林木RAPD标记技术研究进展

综述了RAPD该标记在国内外林木遗传图谱构建、群体遗传多样性分析、系统进化研究、品种分类鉴定、DNA指纹分析和性状遗传品质改良等方面的研究进展和发展趋势, 指出随着理论和实验技术研究的不断深入, 分子标记技术将使林业生产迈上新的台阶.