Advances in tissue engineering

Tissue engineering is a newly developed specialty involved in the construction of tissues and organs either in vitro or in vivo. Tremendous progress has been achieved over the past decade in tisse construction as well as in other related areas, such as bone marrow stromal cells, embryonic stem cells and tissue progenitor cells. In our laboratory, tissues of full-thickness skin, bone, cartilage and tendon have been successfully engineered, and the engineered tissues have repaired full-thickness skin wound, cranial bone defects, articular cartilage defects and tendon defects in animals. In basic research areas, bone marrow stromal cells have been induced and transformed into osteoblasts and chondrocytes in vitro. Mouse embryo stem cell lines we established have differentiated into neuron precursor, cardiac muscle cells and epithelial cells. Genetic modifications of seed cells for promoting cell proliferation, delaying cell aging and inducing immune tolerance have also been investigated.     

鲤骨油微胶囊质量特性及固化时间对其的影响

对以复凝聚法制作的鳗骨油微胶囊湿囊的质量特性进行了研究，结果表明，此微囊的耐冻性，耐磨性，酶解特性均良好，并有一定的耐热性，固化时间对其质量特性有显著影响，这种制作微囊的方法未对鳗骨油的酸价，过氧化值等品质指标产生显著的影响。     

成人礼的复兴与重塑

成人礼在当今社会仍有其积极的作用。大力复兴成人礼，不仅要注重形式创新，更要加强内涵建设，以期更好地发挥成人礼的育人功能和社会价值。     

恶性肿瘤骨转移性骨痛的放射性核素治疗概况

综述了^32P,^89Sr,^153Sm等放射性核素治疗骨转移癌骨痛的机制，疗效和副作用，是一种有效的治疗方法。     

辐射等效人工骨功能材料的设计及其实现

作者从X射线和γ光子与物质相互作用出发，根据骨组织的成分分布和辐射衰减特性，提出了射线能量与质量衰减系数之间的相关数学模型。该模型不仅为辐射等效人工骨材料的设计提供了依据，而且能为人工骨材料的选择和配方的确定提供具体的计算方法。     

Interaction of lipid transfer protein with plasma lipoproteins and cell membranes

Summary The hydrophobic lipid components of lipoproteins, cholesteryl ester and triglyceride, are transferred between all lipoproteins by a specific plasma glycoprotein, termed lipid transfer protein (LTP). LTP facilitates lipid transfer by an exchange process in which cholesteryl ester and triglyceride compete for transfer. Thus, LTP promotes remodeling of the lipoprotein structure, and plays an important role in the intravascular metabolism of these particles and in the lipoprotein-dependent pathways of cholesterol clearance from cells. The properties of LTP, its mechanisms of action, its roles in lipoprotein metabolism, and its modes of regulation are reviewed along with recent data that suggest a possible role for this protein in directly modifying cellular lipid composition.     

壮族摩教文化探析

摩教,是壮族先民创造的传统宗教,由布摩传承。摩教崇拜创世神布洛陀为至上神和教主;有整套的法事仪式和相应的经书。摩经是壮族先民企求借助神力来协调人与自然、人与社会、人与人之间的关系以及祈求生存和发展的宗教典籍,折射着壮族的社会发展历程,对研究壮族古代社会经济、文化及道德观念具有重要的历史价值、文化价值和科学价值;摩经中的三元(天、地、水)说是壮族传统的宇宙结构观念,至今仍在民间广为流传;摩经中的公(雄)母(雌)观则是壮族认识世界最基本的哲学思维方式。布摩还以古老的鸡卜作为人神沟通的中介加以广泛应用,并将鸡卜预测与物候历算结合在一起,发明了多功能的骨刻历算器———“甲巴克”,他们经常用它计算日子,预测吉凶,从而使摩教显得更加凝重而神秘     

染色体标本制备在骨髓MSCs核型鉴定中的研究

选取对数生长期人骨髓间充质干细胞，用秋水仙素阻断细胞分裂中期，控制秋水仙素的终浓度和作用时间、低渗时间及胰酶消化显带时间，比较染色体标本制备效果。结果显示，秋水仙素的终浓度0．2μg／ml和作用时间6h，低渗时间35min及胰酶消化时间20s时可制备适合的染色体标本，经核型鉴定为正常二倍体细胞。从而探索出骨髓间充质干细胞染色体制备的适合条件，为骨髓间充质干细胞的进一步研究提供了理论依据和实验基础。     

大豆异黄酮增强大鼠骨密度作用的研究

大豆异黄酮(soybean isoflavone)是新型天然生理活性物质，具有多种生理功能．研究表明：连续饲喂大鼠90天，实验组股骨的长度、重量、骺端骨密度、中点骨密度均显著大于对照组，说明大豆异黄酮具有增强骨密度的作用．     

Cyclosporine resistant effector cells in rabbit skin allografts

Summary Histoincompatible skin grafts in rabbits treated with cyclosporine can permanently engraft but show a transient mononuclear cellular infiltrate. This transient cyclosporine-resistant infiltrate consists of cells which are sensitive to steroids, radiation and cryopreservation. They have the same ACM-1 phenotype and the same characteristics as cyclosporine-sensitive cells.9 January 1987Supported by the Swiss National Research Foundation, Grant No. 3.908-0.83.