唐钢司家营精矿粉制粒性能试验研究

司家营铁矿属新开发矿种,特点是精矿粉粒度极细,通过制粒试验,司家营精粉具有较好的制粒效果,故采用一混、二混的混料和制粒工艺是可行的.     

圆柱绕流运动的GHM模拟

 基于颗粒流体动力学方法(GHM)对不同雷诺数(Re为80~1646)状态下的圆柱绕流问题进行模拟.结果显示,当Re=80时,在圆柱下游有一对较为对称的附着涡;随着雷诺数的增大,流动变得不稳定,圆柱后方的一对附着涡逐渐脱落消失,尾流逐渐变窄.通过圆柱绕流现象的算例研究,讨论了GHM的特点和需要进一步研究的问题.颗粒流体力学方法将流体视为一个离散的系统,将流场离散为弹性流体颗粒,采用赫兹碰撞理论研究颗粒之间的本构关系,处理颗粒所受到的碰撞力;采用帕斯卡原理和声速导数状态方程研究流场的密度差引起的压强差变化,处理颗粒受到的压差力.颗粒流体动力学方法不同于基于流体为连续体假设所建立的N-S方程,具有一定的原始创新意义.     

定喘颗粒止咳平喘作用研究

摘要: 目的研究定喘颗粒的止咳平喘作用,为其临床应用提供药理学依据。方法采用豚鼠离体气管条法、乙酰 胆碱和磷酸组胺混合液致豚鼠哮喘、二氧化硫引咳小鼠和拘橼酸引咳豚鼠等模型,观察定喘颗粒的止咳平喘作用。 结果定喘颗粒能明显抑制磷酸组胺、乙酰胆碱所致豚鼠离体气管条收缩,显著延长豚鼠哮喘潜伏期以及减少小 鼠和豚鼠的咳嗽次数。结论定喘颗粒具有明显的止咳平喘作用。     

应用高效液相色谱法测定康新妇宝颗粒中的绿原酸的含量

采用高效液相色谱法,建立了复方制剂康新妇宝中绿原酸的含量测定方法.平均回收率为97.69%;RSD为1.89%.该法快速、准确、操作简便,可用于产品的质量控制.     

藏传金丹丸对小鼠实验性肝损伤的药效学研究

目的 研究藏传金丹丸的保肝利胆作用. 方法以CCl4 制作动物急性肝损伤模型, 测定血清ALT、AST、TBIL的含量, 观察藏传金丹丸对动物急性肝损伤的影响;采用麻醉大鼠胆汁引流术, 测定正常大鼠的胆汁分泌量及胆汁成分. 结果藏传金丹丸能明显降低CCl4急性肝损伤动物血清ALT、AST的水平;使正常大鼠的胆汁流量明显增加, 降低胆汁中胆固醇的浓度. 结论藏传金丹丸有明显的保肝、利胆作用.     

概念知识粒与概念信息粒的相互转化

在研究概念知识粒和概念信息粒的基础上,进一步讨论了Ⅰ-型概念信息粒、Ⅱ-型概念信息粒和概念知识粒之间的转换关系,并给出了新的转化方法,进一步揭示了概念信息粒和概念知识粒之间的关系。这些结论为生成近似概念和获取近似规则提供了理论基础,促进了粒计算理论的发展。     

RP-HPLC法测肝康颗粒中阿魏酸的含量

建立以高效液相色谱法测定肝康颗粒中阿魏酸含量的方法。采用反相高效液相色谱法测定康颗粒中阿魏酸的含量。高效液色谱条件为:色谱柱,Kromasil C_(18)柱(250 mm×4.6 mm,5 mm);流动相,甲醇-0.085%磷酸(38:62);检测波长316 nm;流速1.0 mL·min~(-1);柱温为25℃。阿魏酸进样量在75.2～752 ng范围内线性关系良好,回归方程为:Y=7066.1X-42190(r=0.9994,n=6);平均加样回收率为99.46%,RSD=1.33%。本方法操作简便、准确、灵敏度高可用于肝康颗粒的质量控制。     

Casein and lactose concentrations in milk of 31 species are negatively correlated

Summary Casein and lactose concentrations in milks of various species vary by at least 1–2 orders of magnitude, yet no single species secretes both components at either the high or the low end of the ranges. This pattern of variation could result from evolutionary adaptations in a single secretory mechanism.     

Cellular microbiology of intracellular <Emphasis Type="Italic">Salmonella enterica</Emphasis>: functions of the type III secretion system encoded by <Emphasis Type="Italic">Salmonella</Emphasis> pathogenicity island 2

The facultative intracellular pathogen Salmonella enterica resides in a special membrane compartment of the host cell and modifies its host to achieve intracellular survival and proliferation. The type III secretion system encoded by Salmonella pathogenicity island 2 (SPI2) has a central role in the interference of intracellular Salmonella with host cell functions. SPI2 function affects antimicrobial defense mechanisms of the host, intracellular transport processes, integrity and function of the cytoskeleton and host cell death. These modifications are mediated by translocation of a large number of effector proteins by the SPI2 system. In this review, we summarize recent work on the cellular phenotypes related to SPI2 function and contribution of SPI2 effector proteins to these manipulations. These studies reveal a complex set of pathogenic interferences between intracellular Salmonella and its host cells.Received 11 June 2004; received after revision 8 July 2004; accepted 12 July 2004     

Secretion and regulatory mechanism of leptin during pregnancy in the golden hamster （Mesocricetus auratus）

Leptin, a 16 kDa polypeptide mainly secreted by white adipose tissue, has important function on the regulation of food intake and energy expenditure[1]. High concentration of leptin in the circulation suppresses food- intake, increases energy expenditure and therefore decreases the body weight; Accordingly, low concentration of leptin in the circulationstimulates food intake, decreases energy expenditure andincreases the body weight[1]. Normally, leptin level in thecirculation correlates with …