锰-硼钢等温转变曲线河湾形状及其形成机制探讨

本文通过对不同成分的锰－硼钢的等温转变曲线的测试分析．讨论了锰、硼的单独作 用及锰－硼交互作用对转变曲线形状及位置的影响。在此基础上提出：锰－硼钢等温转变 曲线河湾形状的形成原因是由于河湾所在温度范围内锰、硼之间较强的交互作用所引起 的锰、硼偏聚的相互促进而产生较强的溶质拖曳作用的结果。     

中国云南与东盟地缘架构科技资源战略因素比较研究

中国云南与东盟的环境资源、人力资本、技术和技术知识集群可以大大提高国家的实力，这对于技术创新和扩散的绝对影响以及地区产业结构的发生相对位移的意义都有可能提高区域经济增长波动的安全边际。     

VB环境下非接触式射频IC卡读写系统的开发设计

针对常规IC卡读写系统的缺点与不足,设计出在VB环境下的非接触式射频IC卡读写系统.本系统由计算机、读写器、IC卡组成[1].非接触式IC卡读写器采用具有最新Mifare技术的11T6射频读写模块,配以天线、RS232串口便可与计算机实现信息交换[2],在VB环境下,编程时通过调用动态连接库中的卡操作函数,便可实现对Mifare卡的读写操作[3].     

完美T形树的匹配唯一性

研究了完美T形树T（l1,l2,l3)的匹配唯一性，给出了其匹配唯一的充分必要条件，定理A 设G=T（l1,l2,l3)是T形树，若l1,l2,l3至少有一对相等，则G必匹配等价于一类Q∪P型图。定理B 设G=T（l1,l2,l3)是完美T形树，则图G匹配唯一的充分必要条件是l1,l2,l3互不相等。     

合成气在超临界流体及F-T重质烃中的扩散行为研究

对CO和H2在483K、3．5MPa条件下，在充满F－T合成产物（平均相对分子质量400）或超临界正戊烷的催化剂微孔内的扩散速率、孔内气体浓度分布以及催化剂的内表面利用率进行了模拟计算。结果表明合成气在F－T产物中的扩散速率比超临界介质中低得多，从而造成了气相反应中从催化剂孔中到孔内显著的合成气浓度梯度及催化剂内表面利用率的下降，从理论上解释了超临界条件下CO转化率和烃收率优于气相反应的原因。     

中甸鸢尾的核型分析

首次报道中旬鸢尾的染色体数目和核型分析。结果如下：中甸鸢尾核型公式为K(2n)=28=20m 4sm 4st。     

一类T_(BOS)~n 唯一路径簇构造与图形特性分析

应用布尔序集关系理论，研究了一类典型Ｔ _ＢＯＳ^ｎ 唯一路径簇的构造与实现方法．同时给出基本图形特性的分析．     

Immune responses to DNA vaccines

DNA vaccines, based on plasmid vectors expressing an antigen under the control of a strong promoter, have been shown to induce protective immune responses to a number of pathogens, including viruses, bacteria and parasites. They have also displayed efficacy in treatment or prevention of cancer, allergic diseases and autoimmunity. Immunologically, DNA vaccines induce a full spectrum of immune responses that include cytolytic T cells, T helper cells and antibodies. The immune response to DNA vaccines can be enhanced by genetic engineering of the antigen to facilitate its presentation to B and T cells. Furthermore, the immune response can be modulated by genetic adjuvants in the form of vectors expressing biologically active determinants or by more traditional adjuvants that facilitate uptake of DNA into cells. The ease of genetic manipulation of DNA vaccines invites their use not only as vaccines but also as research tools for immunologists and microbiologists. Received 26 October 1998; received after revision 3 December 1998; accepted 3 December 1998     

Dexamethasone enhances CTLA-4 expression during T cell activation

T cell activation is enhanced by the costimulatory interaction of B7 on antigen-presenting cells and CD28 on T cells, resulting in long-term T cell proliferation, differentiation and production of large amounts of cytokines, such as interleukin (IL)-2. CTLA-4 is a co-stimulation receptor that shares 31% homology with CD28 and binds B7 family members with higher affinity. CTLA-4 is transiently expressed intracellularly and on the cell surface following activation of T cells. We have studied the kinetics of CTLA-4 expression and the effects of dexamethasone on CTLA-4 expression during T cell activation in cultures of mouse spleen cells stimulated by a mixture of immobilized anti-CD3 and anti-CD28 monoclonal antibodies (anti-CD3/CD28 mAb) or concanavalin A (ConA). CTLA-4 expression peaked on day 2 and returned to background levels after 7 days. Dexamethasone was found to potentiate CTLA-4 expression in a dose-dependent manner with an EC₅₀ effective concentration 50%) of about 10⁻⁸ M. In contrast, other immunosuppressive agents, such as rapamycin or cyclosporin A had no or an inhibitory effect on CTLA-4 expression, respectively. Dexamethasone also stimulated CD28 expression, but inhibited IL-2R expression during anti-CD3/CD28 mAb-induced mouse splenic T cell activation. Western blot analyses of lysates of activated mouse T cells showed that dexamethasone increased CTLA-4 protein levels twofold during anti-CD3/CD28 mAb-induced activation. Dexamethasone also enhanced CTLA-4 messenger RNA twofold as quantified by ribonuclease protection assay. The effects of dexamethasone on CTLA-4 expression were glucocorticoid-specific and completely inhibited by the glucocorticoid receptor antagonist mifepristone (RU486), indicating that the effect of dexamethasone on CTLA-4 expression is mediated through the glucocorticoid receptor. In conclusion, the immunosuppressive agent dexamethasone actually stimulates CTLA-4 expression, which is involved in downregulation of T cell activation. Received 19 May 1999; received after revision 13 July 1999; accepted 13 July 1999     

ISDN标准接入的多功能数字终端

论述了综合业务数字网（ＩＳＤＮ）及其标准用户──网络接口的基本概念；对用户网络接口的体系结构作了较为详细的说明，给出了具体的软件实现方法和硬件接口电路（ＳＮＩＣ）．在此基础上，提出了ＩＳＤＮ标准数字话音终端和基于基本接入能力（２Ｂ＋Ｄ）的多功能数字终端的设计方案。