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排序方式: 共有408条查询结果,搜索用时 250 毫秒
161.
For an odd integer n ≥ 7, this paper presented a class of n-variable rotation symmetric Boolean functions (RSBFs) with optimum algebraic immunity. The nonlinearity of the constructed functions is determined. 相似文献
162.
Immunological memory allows for rapid and effective protective immunity to previously encountered pathogens. New insights in understanding specific memory differentiation and function have now indicated that in addition to providing enhanced immunity, an important purpose of immunological memory is to provide immediate protection at all sites of the body, including non-lymphoid tissues. Effector memory CD8 T cells have the capacity to reside long-term at epithelial surfaces, where they allow for rapid containment of the invading pathogens at the local entry site and prevent systemic spreading and excessive immune responses. The accumulation of tissue-specific memory T cell subsets, together with cross-reactivity of these antigen-experienced T cells even to unrelated pathogens, provides flexibility and expansion of their specificity repertoire that over time greatly surpasses that of the declining na?ve T cell populations. This review will discuss new insights into T cell memory. We will focus in particular on the generation and function of effector memory CD8 T cells at the intestinal mucosa, which represents one of the largest entry sites for pathogens. 相似文献
163.
刘丽珏 《高技术通讯(英文版)》2009,15(2):126-130
A co-evolutional immune algorithm for the optimization of a function with real parameters is de-scribed.It uses a cooperative co-evolution of two populations,one is a population of antibodies and theother is a population of successful mutation vectors.These two population evolve together to improve thediversity of the antibodies.The algorithm described is then tested on a suite of optimization problems.The results show that on most of test functions,this algorithm can converge to the global optimum atqu... 相似文献
164.
toll样受体和nod受体在天然免疫应答中是重要的家族。激发配体促进受体相互作用的精确检测从而导致多重信号的形成和多级信号转导的触发。这个过程能导致促炎因子的上调、细胞凋亡和调控其他免疫防御。最近,在这些受体家族中识别激活配体和配体的分子基础的检测上有重大进展。理解这些过程,对于新的疫苗佐剂的开发、感染性疾病的治疗、炎症反应和潜在的疾病甚至癌症,都提供了必要的信息。 相似文献
165.
D. Robinette S. Wada T. Arroll M. G. Levy W. L. Miller E. J. Noga 《Cellular and molecular life sciences : CMLS》1998,54(5):467-475
Three antibacterial proteins were isolated from acid extracts of channel catfish (Ictalurus punctatus) skin by cation exchange chromatography and reverse-phase high-pressure liquid chromatography. The molecular masses of the
proteins were 15.5, 15.5 and 30 kD as determined by SDS-polyacrylamide gel electrophoresis. Mass spectrometry, amino acid
composition and amino acid sequence data suggest that the most abundant protein is closely related to histone H2B. The H2B-like
protein was inhibitory to Aeromonas hydrophila and Saprolegnia spp., which are important bacterial and fungal pathogens of fish. These findings suggest that histones may be important defensive
molecules in fish.
Received 22 December 1997; received after revision 5 March 1998; accepted 5 March 1998 相似文献
166.
小鼠皮肤移植特异耐受性的获得 总被引:4,自引:0,他引:4
王重庆 《北京大学学报(自然科学版)》1998,34(4):481-487
通过2个不同品系小鼠间进行皮肤移植,研究免疫系统产生特异耐受的机制。要获得对异体抗原的特异性耐受的机制。要获得对异体抗原的特异性耐受,必要包括对中淋巴器官中免疫效应细胞的特样伤,并同时诱导中枢免疫器官将其作为“自我”物质进行识别,导致系列克隆流产。 相似文献
167.
Immunology has become as an attractive discipline of biomedical science in the 21st century,integrated with the rapid development of molecular biology,cell biology,structural biology,genetics and other branches in life sciences.A special issue of Sci China Life Sci was published in February 2010 to highlight recent progresses in immunology.Six review articles focusing on various specific topics were contributed by leading scientists who work in respective fields of immunology.Some progresses of immunology research in China are also described. 相似文献
168.
169.
Windows系统下的计算机病毒免疫技术 总被引:1,自引:0,他引:1
随着计算机病毒危害的日益严重,计算机病毒免疫技术也越来越凸显其重要地位。本文首先简单介绍了生物免疫系统对于计算机病毒免疫的启发,接着详细讨论了目前流行的对计算机病毒免疫的定义,分析了计算机病毒免疫的方法策略以及局限性,最后对流行的冰河木马如何免疫进行了特例分析。 相似文献
170.
本试验测定了6窝母猪免疫后产小猪0、1、7、14、21、28、35、42日龄O型口蹄疫母源抗体消长情况和首免、二免免疫抗体测定。结果表明:未吃初乳的0日龄仔猪均无母源抗体,1日龄仔猪母源抗体滴度达到高峰,以后逐渐降低;口蹄疫母源抗体对1~14日龄的仔猪有保护,部分仔猪在21日龄还有保护。28~35日龄首免后21日其免疫抗体合格率低于70%,28日后达到峰值86.7%,一个月后再免一次,则有效免疫抗体水平可维持较长时间,以后逐渐降低,至5个月后已不能保护,种猪此时须再次免疫接种猪口蹄疫疫苗。 相似文献