掺纳米Al2O3的纳米8YSZ相变及电导率

掺8mol%Y2O3的纳米ZrO2粉体中加入0－5wt%纳米Al2O3，在1100℃、1200℃、1300℃不同温度下烧结2h，烧结样品在烧结温度达1200℃以上，掺1wt%以上的纳米Al2O3的四方相完全转变为立方相。初步探讨掺纳米Al2O3的8YSZ陶瓷烧结体相变机理及纳米Al2O3对8YSZ烧结体的晶参数和电导率影响。     

非酸催化合成3,9-二苯基-2,4,8,10-四氧杂螺[5,5]-十一烷

利用苯甲醛与季戊四醇在非酸催化剂的作用下 ,合成了聚缩醛螺胞二醚的先导化合物3,9-二苯基 - 2 ,4,8,1 0 -四氧杂螺 [5 ,5 ]-十一烷 .考察了催化剂、反应物的摩尔比、带水剂、反应温度等对反应的影响 .利用FTIR、TG及HNMR对标题化合物的结构进行了表征 ,产品的最高收率可达 88%以上 .     

苏里格庙地区盒8段高渗储层成岩相研究

针对苏里格庙地区盒8段砂岩强烈的成岩作用是造成储层非均质性强的主要原因，不同的沉积微相其胶结类型不同，从而导致酸性水溶蚀次生孔隙发育的程度迥异。通过沉积微相分析以及大量岩石显微薄片的观察，总结出7种苏里格庙地区中二叠统石盒子组盒8段砂岩储层成岩相，并分析了5种沉积充填类型（序列）与成岩相的关系。总结出高渗储层发育的有利成岩相带为净砂岩溶蚀相和净砂岩弱压实弱胶结成岩相，它们主要发育在辫状河心滩和三角洲平原分流河道微相中。根据沉积相展布及成岩相发育规律，对苏里格庙及其外围地区的高渗储集层发育带进行了预测。     

8-氯-10,11-二氢-4-氮杂-5H-二苯并[a,d]-5-环庚酮的合成

以2-氰基-3-甲基吡啶为原料，通过Ritter反应、烷基化、腈化、水解、环化等五步反应成了氯雷他定的重要中间体8-氯-10，11-二氢杂-5H-二苯并[a,d]-5-环庚酮，总收率为25.6%，其结构经核磁共振、质谱等确证。     

固体超强酸S2O2-8 /ZrO2-Al2O3催化合成丙酸苄酯的研究

用固体超强酸S2O8^2-/ZrO2-Al2O3催化苯甲醇与丙酸的酯化反应合成了丙酸苄酯，实验结果表明，S2O8^2-/ZrO2-Al2O3具有较高的催化活性，考察了苯甲醇与丙酸摩尔比、催化剂用量，反应温度，反应时间，带水剂环己烷用量对酯收率的影响，在典型反应条件下（苯甲醇与丙酸摩尔比＝1．2：1，1．0g催化剂/0.33mol丙酸、反应温度160℃，反应时间3．0h和10ml环己烷），丙酸苄酯的收率可以达到86．6％，该催化剂易于回收且可重复使用，具有良好的活性稳定性。     

和解法为主对溃疡性结肠炎患者TNF—α、IL—8和sIL—2R含量调节作用的研究

目的：观察和解法方药治疗效果及探讨和解法为主对溃疡性结肠炎患者的作用机制，为临床用药提供依据。方法：采用和解法方药对30例溃疡性结肠炎患者进行了临床观察，并与西药对照组比较，采用双抗体夹心ELISA法，对和解法方药治疗前后的溃疡性结肠炎患者的TNF－α、IL－8和sIL-2R含量进行了检测。结果：和解法为主中药疗效明显优于西药对照组（P＜0．05），能调节溃疡性结肠炎患者TNF－α、IL－8水平，使其恢复正常状态，但sIL-2R水平未能达到正常。结论：和解法为主治疗溃疡性结肠炎疗效显著，并为预防复发应长期巩固治疗，其作用与调节免疫功能有关。     

西松烯内酯的合成研究——Ⅱ.中间体苏式-7-羟基-3,9,13-三甲基-6-异丙烯基-(2E,8E,12)-十四碳三烯苯硫醚的合成

以香叶醇为原料经过4步反应得到8-溴-3,7-二甲基-(2E,6E)-辛二烯基苯硫醚(7),(7)与(?)牛儿醛在Cr(Ⅱ)作用下立体选择地得到苏式-7-羟基-3,9,13-三甲基-6-异丙烯基-(2E,8E,12)-十四碳三烯苯硫醚.     

Apoptotic cell death in the lactating mammary gland is enhanced by a folding variant of α-lactalbumin

Apoptosis is essential to eliminate secretory epithelial cells during the involution of the mammary gland. The environmental regulation of this process is however, poorly understood. This study tested the effect of HAMLET (human -lactalbumin made lethal to tumor cells) on mammary cells. Plastic pellets containing HAMLET were implanted into the fourth inguinal mammary gland of lactating mice for 3 days. Exposure of mammary tissue to HAMLET resulted in morphological changes typical for apoptosis and in a stimulation of caspase-3 activity in alveolar epithelial cells near the HAMLET pellets but not more distant to the pellet or in contralateral glands. The effect was specific for HAMLET and no effects were observed when mammary glands were exposed to native a-lactalbumin or fatty acid alone. HAMLET also induced cell death in vitro in a mouse mammary epithelial cell line. The results suggest that HAMLET can mediate apoptotic cell death in mammary gland tissue.Received 30 January 2004; received after revision 5 March 2004; accepted 16 March 2004     

NMR study on self-assembled cage complex of hexamethylenetetramine and cucurbit[n]urils

Self-assembled complexes between cage com-pounds cucurbit[n = 5—8]urils and hexamethylenetetramine were studied by using NMR techniques. Experimental results reveal that hexamethylenetetramine can lid cucurbit[5]uril to forming self-assembled capsules in which nothing is encap-sulated yet; the cavity of the cucurbit[7]uril can accommo-date a hexamethylenetetramine molecule to form a self- assembled host-guest inclusion. Moreover, both the cavity interaction of the cucurbit[7]uril with hexamethylenetetra-mine稨Cl and the portal interaction of the dipole carbonyl of the cucurbit[7]uril with hexamethylenetetramine稨Cl lead to form self-assembled capsules in which the hexamethylene-tetramine稨Cl are encapsulated in the hexamethylenetetra-mine稨Cl lidded cucurbit[7]uril. Although the structures of the portal and cavity to cucurbit[5]uril are similar, there is no obvious interaction between decamethylcucurbit[5]uril and hexamethylenetetramine, and also between cucurbit [6]uril or cucurbit[8]uril and hexamethylenetetramine.     

多项式模上全次数除法及其在CAGD中的应用(Ⅰ)

本首先介绍了利用Ｇｒｏｅｂｎｅｒ基求解Ｓｙｚｙｇｙ模生成元的方法,在对方法做出进一步分析的基础上,给出了一元模上的多项式辗转相除法,这种除法相对于已有的方法有许多优点。