应用化学专业《药物化学》课程的教学改革与实践

结合理工类应用化学专业<药物化学>课程的特点,通过进行教学内容的改革、教学方法的改革、实践教学的改革、运用现代化的教学手段等一系列课程的教学改革与实践,达到培养高素质药学专业人才的目标.     

和田玫瑰花红色素的提取及性质研究

文章介绍了和田玫瑰花红色素的提取,研究了光,温度,酸碱性,氧化剂,还原剂,防腐剂,添加剂,金属离子对和田玫瑰花红色素稳定性的影响与理化性质进行了初步研究。玫瑰花红色素的耐光性较好,耐热性很好,可做食品的着色剂,但在使用过程中应尽量避免长时间光照。添加剂对红色素的影响不大,防腐剂对红色素影响不大。Mg2 ,Ba2 ,Na ,K ,Cd2 ,Ca2 对色素的稳定性无影响,Al3 ,Cu2 ,Fe3 对色素有一定影响,在提取和保存过程中应避免使用铁器。     

久治县草地资源基本调查与建设情况

久治县位于青海省果洛藏族自治州的东部，东南部与四川阿阿坝县相邻。东北与甘肃省的玛曲县接壤，西北、西南与本州甘德县、玛班县和达日县毗邻。全县有天然草场73．246万公顷，占土地总面积的83．6％，其中可利用草场66．451万公顷，占草场面积90．7％，全县各类草场平均产草量为23。33公斤／公顷，据县草原站2003年调查，全县草场理论载畜量为245．66万只羊单位，实际载畜量203．45万只羊单位，潜力1．207万只羊单位。     

Studies on molecular interactions between puerarin and PC liposomes

Fluorescence emission spectra, FTIR spectra, zeta potential measurements, and ab initio quantum calculation are used to study the interaction between puerarin and membranes composed of egg phosphatidylcholine (PC) liposome. The hydrophobic interactions cause the puerarin molecule to partition into lipid bilayers with its B-ring, and favor the displacement of acid-base equilibrium of puerarin towards the base form. Due to the hydrogen bond formation between the puerarin hydroxyl groups and polar groups of PC molecules on the water/membrane interface, puerarin can easily intercalate into the organized structure of phospholipids and modulate the membrane function. Our results reveal that the liposome membrane integrity is significantly higher compared with that of empty liposome.     

Dialdehyde starch nanoparticles： Preparation and application in drub carrier

Dialdehyde starch nanoparticles (DASNP) were prepared by the redox reaction of NaIO4 and starch in water-in-oil microemulsion. IR spectrum showed that DASNP had aldehyde groups, and quantitative alkali consumption showed that its dialdehyde content was about (50±5)%. The average diameter of DASNP determined by SEM was about 100 nm. TGA-DTA showed that its thermal stability was better than starch nanoparticle (StNP) and dialdehyde starch (DAS). Its low biological toxicity was detected by cell experiment. Also the best mass ratio of doxorubicin (DOX) to combined DASNP detected by UV-VIS was 15 : 1, and the product was effective for controlled release of DOX. The cell experiment showed that the drug-carrier particle (DOX-DASNP) can release DOX for a long time and strengthened the effect of the anticancer drug. This work demonstrates that the DASNP, which has good thermal stability, small particle size, low biological toxicity, and slowly anticancer drug-releasing to strengthen drug effect, is a potentially useful carrier for anticancer drug.     

惠州市猎豹汽车修理厂结构设计

网架结构的设计适合大空间结构,技术含量较高,用钢量少,工程造价成本低(相对于钢结构的其它形式而言)本文是以惠州猎豹汽车修理厂的结构设计来说明此情况。     

圣氏生物 致力于人类健康事业——全国第一个实现竹叶黄酮、竹叶抗氧化物产业化生产的企业

安吉圣氏生物制品有限公司创建于1998年4月，是浙江省科技厅认定的高新技术企业，重点农业龙头企业和湖州市绿色企业．主要从事于竹子的物理加工和现代深化利用研究。公司所生产的“竹叶黄酮”是国家级新产品，可以用于保健食品原料、医药中间体、食品添加剂、日用化妆品等多个行业。所生产的竹叶抗氧化剂AOB是国内外首创、功能性显著的新型天然食品添加剂。     

沙棘黄色素的提取及性质实验

对从沙棘果实中提取纯天然植物黄色素的工艺进行了探讨，并通过实验，测试了该色素的性质。     

老年痴呆症的药物治疗进展

老年痴呆症（ＡＤ）是一种神经退行性疾病，至今病因未明，且尚无特效药，近年来，临床运用促智药、胆碱酯酶抑制剂、乙酰胆碱释放增强剂、ＮＳＡＩＤ、神经生长因子等药物，对改善症状、延缓疾病表一定的作用。此病的病因及药的治疗有待作更深入的研究 。     

治疗心血管病的毒气

硫化氢 设想一下当走进医院急诊室，映入眼帘的是挂着消毒洗手液、表面擦得一尘不染的墙壁，扑鼻而来的却是一阵臭鸡蛋味。这种视觉和嗅觉上的不协调可能会让人们感到不舒服，但在将来具有臭鸡蛋气味的有毒气体硫化氢很可能会成为医疗机构的常用药物。科学家在去10年间发现，