14种致命癌症的诊断和治疗现状

１４种致命癌症的诊断和治疗现状易家康编译攻克癌症一直是医学界亟需解决的重大课题，据联合国世界卫生组织ＷＨＯ近期报道全球每年死于癌症的人数已逾６６０万之众。目前举世瞩目掀动人心的癌症治疗研究工作有何进展呢？纵观全球可谓喜忧参半──前景不容乐观。令人振奋...     

机械设备的诊断方法与分类

对机械设备的诊断方法进行了系统而详细的分类.根据设备诊断过程的三个主要阶段,即信息检测、特征提取和状态识别,相应地从诊断所检测的信息种类、故障特征提取方法及状态识别方法三个方面对诊断方法进行了分类.     

全国科技名词委公布《中医药学名词》

全国科学技术名词审定委员会于2005年3月正式公布《中医药学名词》。《中医药学名词》是中医药学名词审定委员会经过4年认真细致的审定，完成的我国第一部规范中医药学名词。全书包括：总论，医史文献，中医基础理论，诊断学，治疗学，中药学，方剂学，针灸学，推拿学、养生学、康复学，内科疾病，外科疾病，妇科疾病，儿科疾病，眼科疾病，耳鼻喉科疾病，肛肠科疾病，     

A complete sequence and comparative analysis of a SARS-associated virus （Isolate BJO1）

The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-assoclated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs.We report the complete genome sequence and comparative analysis of an isolate (B J01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 20RFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS-associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to be involved in the immunoreactions between the virus and its host.Two amino acid changes have been detected in the M protein,which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides no evidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of other possible SARS-related pathogen(s).     

技术诊断的研究发展与在土木工程中的应用

综述了技术诊断学在国内外的研究发展状况及技术诊断学在土木工程中的应用．介绍了当前技术诊断的常用方法,重点讨论了对频响函数的监测和高阶固有频率在损伤诊断的应用和存在问题及其研究发展方向．     

WebQuest教学模式在《实验诊断学》教学中的应用

目的：通过对WebQuest在《实验诊断学》中的建构、制作和实践,探讨WebQuest学习模式在《实验诊断学》教学中应用的优势。方法：由教师与学生共建WebQuest模块,建立实验诊断学网站、多媒体素材库,使学生自主地建构所需知识体系。结果：学生通过WebQuest教学法不仅能扎实地掌握《实验诊断学》理论知识,并且还能紧密追踪学科前沿进展,有效地培养临床思维能力和创造性解决问题的能力。结论：在《实验诊断学》课程中开展WebQuest教学法,是现代教学设计的趋势。