妊娠高血压综合征138例临床分析

本文对138例妊娠高血压综合征进行了分析,结果是:发病率为全年分娩人数的6.52%。子痫发病率为0.56%,25岁至29岁的初产妇发病率高达54.34%;长期的精神紧张是重要的发病因素;中西医结合治疗可以减少分娩时出血。并提出硫酸镁等解痉镇静药物所致的子宫收缩乏力性出血、胎盘滞留大出血,应是产科工作者不可忽视的问题。     

Expression of LIF,VEGF, CD57 and CD68 after the transfer of rat embryos to mouse uteri

The high failure rate of interspecific preganacy is a major obstacle to the successful interspectific cloning of mammals,To in vestigate the reasons for the failure of inter-specfic pregnancy between rats and mice,we transferred rat blastocysts into mouse uteri on the third day of pseudopreg -nancy (D3),oure previous study showed that intact rat embryos could still be observed in mouse uteri on D9.In the present study ,we found that expression of CD57 and CD68 increased significantly at the maternal -fetal interface fol-lowing the transfer of rat embryos,Similarly ,Leukaemia inhibitory factor(LIF) expression increased ,but vascular endothelial growth factor(VEGF) expession decreased,In a co-culture system ,the percentage of rat ectoplacental cones (EPCs) with adhesion and outgrowth and outgrowth area on mouse uterine decidual cells were less than that of mouse EPCs,These results indicate that an increase in the immunological rejection response and a decrease in the in vasiveness of rat embryos may be important reasons for the failure of interspecific pregnancy between rat and mouse.     

不良妊娠女性162例生殖道中解脲脲原体生物一群的分布状况研究

目的 研究不良妊娠女性生殖道中解脲脲原体生物一群的感染或定植情况及其血清分型。方法 选择2006年4月。2007年3月间就诊的不良妊娠孕妇162例为研究组,同期入产房待产或引产的健康孕妇89例为对照组,采集其宫颈分泌物进行解脲脲原体（Uu）液体培养,初筛阳性的液体培养基用煮沸法提取DNA,用PCR法进行血清分型。结果 162例不良妊娠女性生殖道中Uu生物一群的阳性检出率为74．69％,健康孕妇阳性检出率为47．19％,差异有显著性意义（P〈0．05）。血清1型、14型及混合型在不良妊娠组中的分布高于健康孕妇组,差异有显著性意义（P〈0．05）;3型、6型在两组中分布差异无显著性意义（P〉0．05）。结论 Uu生物一群与不良妊娠的发生可能有关;1型、14型及混合型可能是致病菌,3型、6型可能正常被携带。     

Advances in interspecific pregnancy

Interspecific pregnancy in which the conceptus and female carrying the pregnancy are of different species is a key step to interspecific cloning. Cloning endangered animals by interspecific pregnancy is such a highlight catching people’s eyes nowadays. In this article, the history of interspecific pregnancy, the methods for establishment of interspecific pregnancy, the corresponding theories, barriers and applied prospects are reviewed. These authors contributed equally to this work.     

33例风湿性心脏病合并妊娠的剖宫产麻醉处理

目的：探讨风湿性心脏病（以下简称风心病）合并妊娠剖宫产的麻醉处理及围术期的综合治疗。方法：对33例妊娠合并风心病剖宫产的临床资料进行回顾性分析。28例产妇选用腰麻-硬脊膜外联合麻醉（简称硬脊麻）,2例选用硬膜外麻醉（简称硬外麻）,1例因术前出现严重心衰及2例需同时行瓣膜置换＋取栓术而行全身麻醉（全麻）。术前、术中积极防治心衰,对已行换瓣术后的产妇围术期合理应用抗凝剂。结果：麻醉过程多数平稳,新生儿除全麻的2例病例Apgar评分在2—3分外,其余均在8分以上,母婴均安全度过围手术期,无1例死亡。仅一例因宫腔出现活动性出血,止血效果差而行全宫切除术,余病例无出现围术期大出血危情。结论：硬脊麻用于风心病合并妊娠剖宫产手术是安全有效的,术前、术中积极正确地防治心衰、改善心功能等综合治疗及围术期合理应用抗凝剂,可降低母婴死亡率。     

输卵管妊娠误诊三例

输卵管妊娠为妇科急腹症，常见但易误诊。医者不要片面依赖尿妊娠试验；避免吸空宫，在诊断早孕做人流术中要注意观察吸出物；要密切观察病情，不要忽视妇科检查及血 Ｈ Ｃ Ｇ 检查。尽早明确诊断，以免延误病情     

剖宫产术中子宫肌瘤剔除术42例临床分析

目的：探讨妊娠合并子宫肌瘤剖宫产术同时行肌瘤剔除术的安全性和可行性。方法：回顾分析我院42例剖宫产同时行子宫肌瘤剔除术,与同期894例妊娠无子宫肌瘤单纯剖宫产术的产妇对照。结果：术后24h出血量、术后病率及术后住院天数与对照组相比无显著性差异（P〉0.05）,手术时间与术中出血量多于对照组（P〈0.05）,肌瘤较大、多发肌瘤的手术时间长、出血多。结论：无论术前或术中发现子宫肌瘤,应尽量同时行子宫肌瘤剔除术,以减少患者第二次手术的痛苦及手术带来的并发症。     

米索前列醇在晚期妊娠中的应用

目的 探讨米索前列醇用于晚期引产的安全性及效果。方法 对201例妊娠35－43周有引产指征的产妇随机分为2组。米索前列醇组102例，对照组99例，分别用米索前列醇50mg阴道后穹窿用药引产及催产素引产。结果2组病人母婴并发症无明显差别，而米索前列醇可促进宫颈成熟，缩短引产至分娩时间，减少催产素用量。结论 米索前列醇引产安全有效，临床上正逐步取代传统的催产素静点引产。     

A study of granulated metrial gland cell differentiation in pregnant,macrophage-deficient,osteopetrotic (op/op) mice

A population of uterine natural killer (NK) cells, commonly called granulated metrial gland (GMG) cells, differentiates in the mouse uterus during normal pregnancy. Little is known regarding the process of differentiation of GMG cells or of other NK cell subsets. It has been suggested that macrophage precursors, under the combined influences of the cytokine growth factors colony stimulating factor-1 (CSF-1) and interleukin-2, become NK-cell like in morphology, pattern of target cell lysis and surface antigen phenotype. Mice expressing the mutation osteopetrosis (op/op) are unable to produce the cytokine CSF-1. To determine whether CSF-1 is required for the successful differentiation of uterine NK cells, implantation sites in pregnant,op/op mice were studied histologically. GMG cell differentiation appeared to progress normally inop/op mice studied between days 7 and 14 of gestation. Thus, the growth factor CSF-1 is not required for differentiation of the uterine NK cell subset known as GMG cells and probably GMG cells do not differentiate from macrophage precursor cells which are deficient inop/op mice.     

山东农田黑线仓鼠种群数量动态及预测预报的初步研究

本文着重研究了黑线仓鼠(Cricetulus barabensis)种群内部因素及环境因子对其种群数量变化的影响,其中4月份的平均胎仔数与当年7～12月份种群数量高峰相关性显著,是预测预报的基础;环境因子中8月份月均气温及极端降水量影响害鼠的怀孕率、胎仔数等,对其种群数量变动有一定影响作用。