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21.
关于图的第二特征标R2(G) 总被引:10,自引:2,他引:8
毛建树 《青海师范大学学报(自然科学版)》2004,(1):18-22
对任意图G,h(G,x)表示图G的伴随多项式,R2(G)表示图G的第二特征标,本文刻画了R2(G)=-2,-1,0,1,2的全部连通图。 相似文献
22.
带有非相参积累的序列统计恒虚警检测器 总被引:2,自引:0,他引:2
雷达检测中,为了改善检测性能经常采用非相参积累的方法以获取高信杂比的目标回波,本文讨论了平方律检波后带有非相参积累的序列统计恒虚警检测器,分析了Swerling起伏目标情况下的检测性能,并介绍了该检测器在实际工作中的一种应用。 相似文献
23.
星星草种群地上生物量形成规律的数学拟合 总被引:3,自引:0,他引:3
在松嫩盐碱草地上,我们对人工种植在碱斑土壤上生长一年、二年、三年、六星星草坪以及野生的天然星星草地中的星星草种群地上生物量的季节动态进行了测定,并进行数学拟合。用Logistic曲线拟合时,抽穗期以前拟合情况较好,但不能很好地拟合星星草种群大生物量后衰老的过程。用一元多次曲线则能很好地拟合星星草种群地上生物量随生育时间的季节动态。 相似文献
24.
利用点群4/mmm的对称性给出了应力作用下的钛酸铋的弹性吉布斯自由能的表达式,并导出了自发应变,介电性质和压电性质。 相似文献
25.
刘金凯 《山东师范大学学报(自然科学版)》2005,20(2):57-58
研究了诺氟沙星—铽(Tb^3 )络合物与核酸(DNA)的相互作用,据此建立了核酸的测定方法,讨论了诺氟沙星—铽与DNA分子之间的结合方式。 相似文献
26.
Science Letters: A synthetic Toll-like receptor 2 ligand decreases allergic immune responses in a mouse rhinitis model sensitized to mite allergen
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It has been proposed that activation of Toll-like receptors (TLRs) plays crucial roles in the polarization of adaptive immune responses. A synthetic Toll-like receptor 2 (TLR2) ligand, Pam3CSK4, has been reported to modulate the balance of Th1/Th2 responses. We evaluated the modulation effect of Pam3CSK4 on allergic immune response in a mouse rhinitis model sensitized to house dust mite allergen (HDM). Mice were sensitized and challenged with Dermatophagoidesfarinae allergen (Der f), and then the allergic mice were treated by Pam3CSK4. Nasal allergic symptoms and eosinophils were scored. Der f-specific cytokine responses were examined in the splenocytes and bronchoalveolar lavage fluid (BALF). Serum level of total IgE was also detected. After establishing a mouse allergic rhinitis model with HDM, we have showed that Pam3CSK4 treatment not only ameliorated the nasal allergic symptoms remarkably but also decreased the eosinophils and total inflammation cells in BALF significantly. Analysis of cytokine profile found that IFN-7 released from either BALF or stimulated splenocytes increased markedly in Pam3CSK4-treated mice, while IL-13 decreased significantly. Moreover, serum level of total IgE was significantly lower in Pam3CSK4-treated mice than in the untreated. Thus, in an allergic rhinitis mouse model developed with HDM, Pam3CSK4 was shown to exhibit an antiallergic effect, indicating its potential application in allergic diseases. 相似文献
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《科学通报(英文版)》2008,(19)
The purposes of this research were to study the stable expression of exogenous gene encoding therapeutic protein in attenuated Salmonella typhimurium, observe the metabolism of oral gene vaccine carried by attenuated Salmonella typhimurium in BALB/c mouse, and investigate the feasibility of prevention and treatment of tumors by the recombinant bacteria. Recombinant plasmid pcDNA3.1 VEGFR2(n1-7) was transformed into competent attenuated Salmonella typhimurium SL3261 to develop oral DNA vaccine SL3261-pcDNA3.1 VEGFR2(n1-7). To observe whether the exogenous gene can be expressed in the recombinant bacteria, PCR was performed to amplify the CMV promoter of the eukaryotic expression vector as the proof of stable expression of exogenous protein; transmission elec- tron microscopy (TEM) was applied to observe the morphology of the recombinant bacteria to confirm that the exogenous gene has no impact on the growth of the bacteria, and then BALB/c mice were immunized with the gene vaccine. After inoculation of the gene vaccine, the recombinant bacteria SL3261 could be detected in the tissues such as small intestine, colon, liver and spleen. And then, mice in each group were challenged with tumor cells. The results of animal experiment showed that tumor growth of the mice in experimental group was inhibited and survival time of immunized mice was prolonged compared with control groups. A higher lymphocyte infiltration in tumors from animals treated with DNA vaccine was observed. Immunohistochemical analysis of tumor samples revealed an en- hanced accumulation of CD8 cytotoxic T lymphocytes, as well as an increase in CD4 cells in the tumors of animals treated with the oral gene vaccine compared to tumors from control group mice. Ultrastructure of the tumor tissue showed that tumor cells in the samples of the immunized mice were well-differentiated. Our research confirmed that the exogenous gene can be stably expressed in the attenuated Salmonella typhimurium and has no impact on the growth of the recombinant bacteria; the exogenous gene can de delivered to the host by attenuated Salmonella typhimurium to produce anti-tumor effect with no obvious cytotoxity to the host. In this study, it is established that attenuated Salmonella typhimurium could be used as a vector for oral gene vaccine, and our study provided a theoretical basis for the body distribution and the metabolism of the recombinant bacteria. This strategy may provide a simple, safe and effective way for the prevention and treatment of tumors. 相似文献
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我国已经颁布了新的存货准则,并于今年年初开始实施,这对于进一步规范企业存货的确认、计量和披露,提高会计信息的相关性和可靠性,完善我国会计准则体系,推动我国证券市场乃至整个社会主义市场经济的发展,将起到积极的作用. 相似文献