预应力砼T型梁反拱设置与质量通病预防

1．武汉市武家山地处软基．京球高速公路跨越时大量采用30m后张预应力砼T型梁，在台座上浇注、张扭，然后用架桥机简支安装，每跨6片．每5-6跨通过桥面简单连续。我标段全长19．3km．主要是桥梁，共计30mt型梁2076片（双幅173孔），这些梁板在安装时，无一不发生了T梁上拱度偏大、T梁顶面超高，从而出现桥面铺装层厚度不足，危及桥面系工程质量的情况，形成了本项目预应力梁式桥上部结构施工中的质量通病。     

篮球运动中学生损伤病因与预防

通过对体育院系学生问卷调查，了解学生在篮球运动中发生运动损伤病因，提出预防措施。     

如何避免现浇混凝土裂缝的产生

混凝土结构在现代工程建设中占有重要地位,但混凝土的裂缝却较为普遍。最近,在有关工程质量问题的新闻报道中,现浇混凝土裂缝成为工程质量的一大问题。这些裂缝大部分表现为:表面龟裂,纵向、横向裂缝以及斜向裂缝。混凝土裂缝影响到结构的整体性、耐久性和美观性,在实际施工中必须对其进行有效控制,避免有害裂缝的产     

国内外交通安全管理之比较

文章通过对欧美、日本等发达国家在道路交通安全宣传教育、事故紧急救援、管理人员严格公正执法、事故损害赔偿归责等方面和我国的交通安全管理情况进行比较分析,试提出我国目前在这些方面存在的问题以及应对措施。     

过度训练:不同发展阶段的神经内分泌变化

综述了关于过度训练状态下机体神经内分泌方面的变化,并对其中一些矛盾的结果提出了可能的解释。     

水泥混凝土的裂缝预防与处理措施

混凝土的裂缝问题是一个普遍存在而又难于解决的工程实际问题,本文对混凝土工程中常见的一些裂缝问题进行了探讨分析,并针对具体情况提出了一些预防、处理措施。     

砖混结构住宅楼墙体裂缝的控制及预防

住宅建设中，砖混结构为主的现象极为普遍，但作为质量通病之一，墙体裂缝却会时常产生。细小的裂缝不易被人重视，不影响使用，但却会降低建筑物的抗震能力。当地震发生时，会引起墙体破坏、坍塌，是一种不安全隐患，必须重视解决，本文就裂缝产生的原因，采取切实可行的措施，预防控制裂缝、浅谈了自己的看法。     

Science Letters： A synthetic Toll-like receptor 2 ligand decreases allergic immune responses in a mouse rhinitis model sensitized to mite allergen

It has been proposed that activation of Toll-like receptors （TLRs） plays crucial roles in the polarization of adaptive immune responses. A synthetic Toll-like receptor 2 （TLR2） ligand, Pam3CSK4, has been reported to modulate the balance of Th1/Th2 responses. We evaluated the modulation effect of Pam3CSK4 on allergic immune response in a mouse rhinitis model sensitized to house dust mite allergen （HDM）. Mice were sensitized and challenged with Dermatophagoidesfarinae allergen （Der f）, and then the allergic mice were treated by Pam3CSK4. Nasal allergic symptoms and eosinophils were scored. Der f-specific cytokine responses were examined in the splenocytes and bronchoalveolar lavage fluid （BALF）. Serum level of total IgE was also detected. After establishing a mouse allergic rhinitis model with HDM, we have showed that Pam3CSK4 treatment not only ameliorated the nasal allergic symptoms remarkably but also decreased the eosinophils and total inflammation cells in BALF significantly. Analysis of cytokine profile found that IFN-7 released from either BALF or stimulated splenocytes increased markedly in Pam3CSK4-treated mice, while IL-13 decreased significantly. Moreover, serum level of total IgE was significantly lower in Pam3CSK4-treated mice than in the untreated. Thus, in an allergic rhinitis mouse model developed with HDM, Pam3CSK4 was shown to exhibit an antiallergic effect, indicating its potential application in allergic diseases.